EVALUATION OF MEAN PLATELET VOLUME AND 25 HYDROXY VITAMIN D LEVELS IN GESTATIONAL DIABETIC WOMEN

Öz

Aim: According to few studies which tried to evaluate mean platelet volume (MPV) and 25 hydroxy vitamin D, have shown conflicting results in gestational diabetic patients. In this study we aimed to compare main platelet volume and 25 hydroxy vitamin D values between gestational diabetic patients and healty individual pregnant womens. Material and method: The patients were selected from 24-28 weeks pregnant people who made gestational diabetes screening and oral glucose tolerance test from obstetric-gynecology, diabetes and endocrinology polyclinics of Okmeydanı Training and Research Hospital. After the searching 52 gestational diabetic patients and 52 healty pregnant women included to the study. We estimated MPV and vitamin D level. In addition, demographic and clinical data of subjects were recorded. Results: Mean platelet volume (MPV) value was found 8,5 ± 1,0 fl and 8,3 ± 1,1 fl. in gestational diabetic and control group respectively. There was no statistically significant differences in MPV value between case and the control group (p>0.05). Mean 25 hydroxy vitamin D value was found 20.5 ± 11.0 ng/ml and 21,1 ± 9,3 ng/ml. gestational diabetic and control group respectively. There was no statistically significant differences in 25 hydroxy (OH) vitamin D value between case and control group. Conclusion: In our study we found no statistically significant differences in MPV and 25-OH vitamin D values between gastational diabetic pregnant group and healty pregnant group.

Anahtar Kelimeler

• Gestational diabetes
• Main platelet volume
• Vitamin D

GESTASYONEL DİYABETLİ KADINLARDA ORTALAMA PLATELET HACMİ VE 25 HİDROKSİ D VİTAMİNİ DÜZEYLERİNİN DEĞERLENDİRİLMESİ.

Öz

Amaç: Gestasyonel diyabeti olan hastalarda ortalama trombosit hacmi (MPV) ve 25-OH hidroksi vitamin D düzeylerini değerlendirmeye çalışan az sayıdaki çalışmaya göre, çelişkili sonuçlar ortaya çıkmıştır. Bu çalışmada gestasyonel diyabetik ve sağlıklı gebelerde MPV ve serum 25-OH vitamin D düzeylerini değerlendirmeyi ve karşılaştırmayı amaçladık. Gereç ve Yöntem: Hastalar Okmeydanı Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum, Diyabet ve Endokrinoloji polikliniklerinden gestasyonel diyabet taraması ve oral glukoz tolerans testi yapılmış 24-28 haftalık gebelerden seçildi. Araştırma sonucunda 52 gestasyonel diyabet hastası ve 52 sağlıklı gebe çalışmaya dahil edildi. MPV ve D vitamini seviyeleri tespit edildi. Ayrıca hastaların demografik ve klinik verileri kaydedildi. Bulgular: Çalışmaya alınan gestasyonel diyabetik gebe grubunun ortalama MPV değeri 8,5 ± 1,0 fl; kontrol grubunda ise ortalama MPV 8,3 ± 1,1 fl saptandı. Çalışmaya alınan hasta grubu ile kontrol grubu arasında ortalama MPV değeri dağılımda istatistiksel olarak anlamlı bir farklılık görülmedi (p>0,05). Gestasyonel diyabetik gebe grubunun ortalama 25-OH vitamin D değeri 20,5 ± 11,0 ng/ml; kontrol grubunda ise 21,1 ± 9,3 ng/ml saptandı. Çalışmaya alınan hasta grubu ile kontrol grubu arasında ortalama 25-OH vitamin D değeri dağılımda istatiksel olarak anlamlı bir farklılık görülmedi (p>0,05) Sonuç: Bizim çalışmamızda gestasyonel diyabetik gebe grubu ile sağlıklı gebe grubu arasında MPV ve 25-OH vitamin düzeyleri arasında istatistiksel olarak anlamlı bir fark saptanmadı.

Anahtar Kelimeler

• Gestasyonel diyabet
• ortalama trombosit hacmi
• D vitamini

Kaynakça

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