Relationship Between Kartagener’s Syndrome and Internal Diseases: Coincidence or Coexistence

Öz

Kartagener’s syndrome (KS) is included in the group of diseases arising from primary ciliary dyskinesia (PCD) and is characterized by the triad of situs inversus, chronic sinusitis and bronchiectasis.Patients with PCD, including KS, may present with various manifestations, such as male and female infertility, olfactory disorders, ophthalmopathy and hydrocephalus resulting from ciliary dysfunction.In our review of the literature, many rheumatic, renal, and malignant diseases and KS relationships have been reported. We think, as suggested by other authors , that chronic infectious processes, impaired mucociliary clearance and chronic hypoxia may play an important role in the development of KS coincidence with internal diseases.We write  this letter to draw attention to this issue.

Anahtar Kelimeler

• Kartagener’s syndrome
• internal disease
• rheumatic disease

Kartagener Sendromu ile dahili hastalıkların ilişkisi: Tesadüf mü?, Birliktelik mi?

Öz

Kartagener sendromu,situs inversus, bronşektazi ve kronik sinüzit triadı ile karakterize bir siliyer diskinezi bozukluğudur. Kartagener sendromu, primer silier bozukluğuna bağlı olarak kadın ve erkek infertilitesi, koku alma ve görme kusuru, hidrosefali gibi klinik bulgular verebilir. Literatür araştırmamızda Kartagener sendromu ile birlikte romatizmal, renal ve malign hastalıkların birarada görüldüğü gözlenmektedir.Kronik enfeksiyöz süreçler, bozulmuş mukosilier klirensin Kartagener sendromu ve dahili hastalıkların gelişiminde rolu olduğu düşünülmektedir. Biz de dahili hastalıklar ve Kartagener sendromunun birlikte görülebileceğine dikkat çekmek için bu mektupu yazdık.

Anahtar Kelimeler

• Kartagener Sendromu
• dahili hastalıklar

Kaynakça

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