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Kronik alerjik rinitli hastalarda cilt prick test sonuçları: Ev hanımları ev tozu akarlarına bağlı alerjik rinit gelişimi için riskli meslek grubundadır

Yıl 2019, Cilt: 9 Sayı: 3, 230 - 234, 30.09.2019
https://doi.org/10.16899/jcm.578203

Öz

Amaç: Alerjik rinit (AR), nazal
epitelyum inflamasyonuna bağlı olarak ortaya çıkan ve yaşam kalitesini olumsuz
yönde etkileyen semptomlarla karakterize sık görülen bir hastalıktır. Bu
çalışmanın amacı, cilt prick testi pozitif olan alerjik rinitli hastaların
demografik ve klinik özelliklerini ortaya koymaktır.

Gereç ve Yöntem: Pozitif cilt prick
testi olan alerjik rinitli hastalar analiz edildi. Test edilen alerjenler: Çayır,
tahıl + çayır, ağaçlar 1 (erken çiçeklenenler ), ağaçlar 2 (geç çiçeklenenler),
ev tozu akarlarıdır (Dermatophagoides pteronyssinus (DP), Dermatophagoides
farinae (DF), Tyrophagus putrescentiae (TP), Lepidoglyphus destructor (LD) ve
Acarus siro (AS)).

Bulgular: Çalışmaya dahil
edilen 202 hastanın 145’i kadın (ortalama yaş 32.42 ±12.81) ve 57‘si erkekti
(ortalama yaş 28.44 ± 11.5). En sık tespit edilen alerjenler; DF, DP, çayır,
tahıl + çayır grubuydu. Cilt prick testinin Tyrophagus için pozitifliği istatistiksel
olarak kadınlarda anlamlıydı (p=0.04). Nazal akıntı, dispne, kaşıntı,
halsizlik, yorgunluk semptomları kadınlarda erkeklere oranla daha fazla
bildirildi. DF, DP, TP and LD grubu alerjen duyarlılığı ev hanımlarında
istatistiksel olarak anlamlı bulundu (p<0.05). Dispne, hışıltılı solunum ve
kaşıntı ev hanımlarında istatistiksel olarak daha sık bulundu (p<0.05).







Sonuç : Ev hanımları, ev tozu akarlarına
bağlı alerjik rinit gelişimi için  riskli
meslek grubundadır. 

Kaynakça

  • 1. Linneberg A. The increase in allergy and extended challenges. Allergy. 2011; 66 (Suppl): 95. 1–3.
  • 2. Prasad R, Verma SK, Dua R, Kant S, Kushwaha RA, Agarwal SP. A study of skin sensitivity to various allergens by skin prick test in patients of nasobronchial allergy. Lung India. 2009; 26: 70–73.
  • 3. Khazaei HA, Moulaei NA, Tabatabaei SNA, Khazaei A, Khosravi A. The Effect of Smoke Cigarette on Immune Responses of AR Patients. Biosc Biotech Res Asia. 2014; 11(2): 925–30
  • 4. Wheatley LM, Togias A. Clinical practice. Allergic rhinitis. N Engl J Med. 2015; 29; 372(5): 456-63.
  • 5. Liu Y, Peng J, Zhou Y, Cui Y. Comparison of atopy patch testing to skin prick testing for diagnosing mite-induced atopic dermatitis: a systematic review and meta-analysis. Clin Transl Allergy. 2017 Nov 29; 7: 41.
  • 6. Chiriac AM, Bousquet J, Demoly P. In vivo methods for the study and diagnosis of allergy. In: Adkinson NF Jr, Bochner BS, Burks AW, Busse WW, Holgate ST, Lemanske RF, O'Hehir RE Jr, editors. Middleton's allergy principles and practice. 8th ed. Philadelphia: Elsevier; 2013. pp. 1119–1132.
  • 7. Bousquet J, Heinzerling L, Bachert C, et all. Global Allergy and Asthma European Network; Allergic Rhinitis and its Impact on Asthma. Practical guide to skin prick tests in allergy to aeroallergens. Allergy. 2012 Jan;67(1):18-24.
  • 8. Nevis IF, Binkley K, Kabali C. Diagnostic accuracy of skin-prick testing for allergic rhinitis: a systematic review and meta-analysis.Allergy Asthma Clin Immunol. 2016 Apr 27; 12:20.
  • 9. Kang MG, Kim MY, Song WJ, et all. Patterns of Inhalant Allergen Sensitization and Geographical Variation in Korean Adults: A Multicenter Retrospective Study.Allergy Asthma Immunol Res. 2017 Nov; 9(6): 499-508
  • 10. Comert S, Demir AU, Karakaya G, Kalyoncu AF. Minimum prick test panel for adult patients with asthma and rhinitis in Ankara, Turkey. J Asthma. 2014 May; 51(4): 417-22.
  • 11. Holopainen E, Salo OP, Tarkiainan E, Malmberg H. The most important allergens in allergic rhinitis. Acta Otolaryngol. 1979; 360: 16–8.
  • 12. Lou H, Ma S, Zhao Y, et all. Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China. Sci Rep. 2017 Aug 24; 7(1): 9286.
  • 13. Wang Z, Gao Y, Zheng Y. Analysis on allergens in patients with allergic rhinitis in Urumqi Xinjiang. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Aug;29(15):1328-31.
  • 14. Khazaei HA, Khazaei B, Dashtizadeh GA, Mohammadi M. Cigarette Smoking and Skin Prick Test in Patients With Allergic Rhinitis. Int J High Risk Behav Addict. 2015 Sep 1;4(3):e23483.
  • 15. Thomas WR, Smith WA, Hales BJ. The allergenic specificities of the house dust mite. Chang Gung Med J. 2004;27: 563–569.
  • 16. Cui Y, Zhou P, Peng J, et all. Cloning, sequence analysis, and expression of cDNA coding for the major house dust mite allergen, Der f 1, in Escherichia coli. Braz J Med Biol Res. 2008; 41(5): 380–388.
  • 17. Tee RD, Gordon DJ, Gordon S, et all. Immune response to flour and dust mites in a United Kingdom bakery. Br J Ind Med. 1992 Aug;49(8):581-7.
  • 18. Nuñez NK, da Cunha AA, Dos Santos Dutra M, et all. Acute and chronic exposure to Tyrophagus putrescentiae induces allergic pulmonary response in a murine model. Asia Pac Allergy. 2016 Jan; 6(1): 48-55.
  • 19. Akdemir C, Gurdal H. House dust mite in Kutahya, Turkey. [Turkish] Turkiye Parazitol Derg 2005;29(2):110-115.

Skin prick test results in patients with chronic allergic rhinitis: Housewives are risky occupational group for the development of allergic rhinitis due to house dust mites

Yıl 2019, Cilt: 9 Sayı: 3, 230 - 234, 30.09.2019
https://doi.org/10.16899/jcm.578203

Öz

Background/Aims: Allergic Rhinitis (AR) is a common disorder that negatively effects the quality of life with symptoms due to the inflammation of nasal epithelium. Objective of this study is to determine the general demographical and clinical features of patients with AR, who had positive skin prick test (SPT) results.  

Methods: Patients diagnosed as AR with positive SPT results were analyzed. The allergens tested were: grasses, cereals+grasses , trees 1 (early flowering), trees 2 (late flowering), house-dust mites ( Dermatophagoides pteronyssinus (DP), Dermatophagoides farinae (DF), tyrophagus putrescentiae (TP), lepidoglyphus destructor (LD) and acarus siro (AS). 

Results: Of the total 202 patients, 145  female (with a mean age of 32.42 ±12.81 years) and 57  male (with a mean age of 28.44 ± 11.5 years) were included in the study. The most common allergens determined were; DF, DP, cereals+grasses and grasses. Tyrophagus significantly was more common in females (p:0.04). Nasal discharge, dyspnea, itching and weakness-tiredness were reported to be more common in females compared with males. DF, DP, TP and LD were statistically significantly more common in housewives (p<0.05). Dyspnea, wheezing and itching were statistically significantly more common in housewives (p<0.05).

Conclusions: Housewives
are risky occupational group for the development of allergic rhinitis due to
house dust mites







Kaynakça

  • 1. Linneberg A. The increase in allergy and extended challenges. Allergy. 2011; 66 (Suppl): 95. 1–3.
  • 2. Prasad R, Verma SK, Dua R, Kant S, Kushwaha RA, Agarwal SP. A study of skin sensitivity to various allergens by skin prick test in patients of nasobronchial allergy. Lung India. 2009; 26: 70–73.
  • 3. Khazaei HA, Moulaei NA, Tabatabaei SNA, Khazaei A, Khosravi A. The Effect of Smoke Cigarette on Immune Responses of AR Patients. Biosc Biotech Res Asia. 2014; 11(2): 925–30
  • 4. Wheatley LM, Togias A. Clinical practice. Allergic rhinitis. N Engl J Med. 2015; 29; 372(5): 456-63.
  • 5. Liu Y, Peng J, Zhou Y, Cui Y. Comparison of atopy patch testing to skin prick testing for diagnosing mite-induced atopic dermatitis: a systematic review and meta-analysis. Clin Transl Allergy. 2017 Nov 29; 7: 41.
  • 6. Chiriac AM, Bousquet J, Demoly P. In vivo methods for the study and diagnosis of allergy. In: Adkinson NF Jr, Bochner BS, Burks AW, Busse WW, Holgate ST, Lemanske RF, O'Hehir RE Jr, editors. Middleton's allergy principles and practice. 8th ed. Philadelphia: Elsevier; 2013. pp. 1119–1132.
  • 7. Bousquet J, Heinzerling L, Bachert C, et all. Global Allergy and Asthma European Network; Allergic Rhinitis and its Impact on Asthma. Practical guide to skin prick tests in allergy to aeroallergens. Allergy. 2012 Jan;67(1):18-24.
  • 8. Nevis IF, Binkley K, Kabali C. Diagnostic accuracy of skin-prick testing for allergic rhinitis: a systematic review and meta-analysis.Allergy Asthma Clin Immunol. 2016 Apr 27; 12:20.
  • 9. Kang MG, Kim MY, Song WJ, et all. Patterns of Inhalant Allergen Sensitization and Geographical Variation in Korean Adults: A Multicenter Retrospective Study.Allergy Asthma Immunol Res. 2017 Nov; 9(6): 499-508
  • 10. Comert S, Demir AU, Karakaya G, Kalyoncu AF. Minimum prick test panel for adult patients with asthma and rhinitis in Ankara, Turkey. J Asthma. 2014 May; 51(4): 417-22.
  • 11. Holopainen E, Salo OP, Tarkiainan E, Malmberg H. The most important allergens in allergic rhinitis. Acta Otolaryngol. 1979; 360: 16–8.
  • 12. Lou H, Ma S, Zhao Y, et all. Sensitization patterns and minimum screening panels for aeroallergens in self-reported allergic rhinitis in China. Sci Rep. 2017 Aug 24; 7(1): 9286.
  • 13. Wang Z, Gao Y, Zheng Y. Analysis on allergens in patients with allergic rhinitis in Urumqi Xinjiang. Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2015 Aug;29(15):1328-31.
  • 14. Khazaei HA, Khazaei B, Dashtizadeh GA, Mohammadi M. Cigarette Smoking and Skin Prick Test in Patients With Allergic Rhinitis. Int J High Risk Behav Addict. 2015 Sep 1;4(3):e23483.
  • 15. Thomas WR, Smith WA, Hales BJ. The allergenic specificities of the house dust mite. Chang Gung Med J. 2004;27: 563–569.
  • 16. Cui Y, Zhou P, Peng J, et all. Cloning, sequence analysis, and expression of cDNA coding for the major house dust mite allergen, Der f 1, in Escherichia coli. Braz J Med Biol Res. 2008; 41(5): 380–388.
  • 17. Tee RD, Gordon DJ, Gordon S, et all. Immune response to flour and dust mites in a United Kingdom bakery. Br J Ind Med. 1992 Aug;49(8):581-7.
  • 18. Nuñez NK, da Cunha AA, Dos Santos Dutra M, et all. Acute and chronic exposure to Tyrophagus putrescentiae induces allergic pulmonary response in a murine model. Asia Pac Allergy. 2016 Jan; 6(1): 48-55.
  • 19. Akdemir C, Gurdal H. House dust mite in Kutahya, Turkey. [Turkish] Turkiye Parazitol Derg 2005;29(2):110-115.
Toplam 19 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Orjinal Araştırma
Yazarlar

Tarkan Ozdemir 0000-0002-9344-7586

Benan Kasapoglu 0000-0003-3858-0103

Mustafa Turkkani Bu kişi benim 0000-0001-7662-7924

Cigdem Ozdilekcan 0000-0001-5335-0571

Fuat Erel 0000-0002-4788-8161

Yayımlanma Tarihi 30 Eylül 2019
Kabul Tarihi 2 Eylül 2019
Yayımlandığı Sayı Yıl 2019 Cilt: 9 Sayı: 3

Kaynak Göster

AMA Ozdemir T, Kasapoglu B, Turkkani M, Ozdilekcan C, Erel F. Skin prick test results in patients with chronic allergic rhinitis: Housewives are risky occupational group for the development of allergic rhinitis due to house dust mites. J Contemp Med. Eylül 2019;9(3):230-234. doi:10.16899/jcm.578203