Yıl 2019, Cilt 9 , Sayı 4, Sayfalar 412 - 416 2019-12-31

Abstract

 Son yıllarda dünyada hem obezite hem de astım görülme sıklığı artmıştır. Her iki hastalığın birlikte artış göstermesi obezitenin mekanik etkisi, inflamasyon, oksidatif stres, genetik ve epigenetik faktörler, yaşam tarzı ve çevresel maruziyetler gibi birtakım ortak mekanizmalar ile açıklanmaya çalışılmaktadır. Obezitenin eşlik ettiği astımda semptomlar daha şiddetlidir, atak nedeni ile hastaneye yatış sıklığı artmıştır ve tedaviye cevap alınması güçtür. Ayrıca astım tedavilerinin pek çok yan etkisi vardır. Obezite ve astım arasındaki ilişki mekanizmalarının netleşmesi ile yeni tedavi yaklaşımları ortaya konmuştur. Diyet ve egzersiz ile obez astımlıların klinik seyrinin iyileştiği gösterilmiştir. Obezite cerrahisi ile olumlu sonuçlar bildirilmektedir. Metabolik sendromun eşlik ettiği hastalarda metformin ve statinlerin fayda sağladığını gösteren çalışmalar vardır. Antioksidan içeren diyetlerin de astım kontrolünde yararı vardır. Ancak bu tedavi seçeneklerine yönelik daha kapsamlı çalışmalara ihtiyaç duyulmaktadır.





astım, obezite
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Birincil Dil tr
Bölüm Derleme
Yazarlar

Orcid: 0000-0002-4946-7029
Yazar: Buket MERMİ̇T Çİ̇Lİ̇NGİ̇R (Sorumlu Yazar)
Kurum: VAN YÜZÜNCÜ YIL ÜNİVERSİTESİ, TIP FAKÜLTESİ
Ülke: Turkey


Orcid: 0000-0002-3504-8915
Yazar: Hülya GÜNBATAR
Kurum: YÜZÜNCÜ YIL ÜNİVERSİTESİ, TIP FAKÜLTESİ
Ülke: Turkey


Tarihler

Yayımlanma Tarihi : 31 Aralık 2019

EndNote %0 Journal of Contemporary Medicine ASTIM VE OBEZİTE %A Buket MERMİ̇T Çİ̇Lİ̇NGİ̇R , Hülya GÜNBATAR %T ASTIM VE OBEZİTE %D 2019 %J Journal of Contemporary Medicine %P -2667-7180 %V 9 %N 4 %R %U