Yıl 2020, Cilt 10 , Sayı 4, Sayfalar 481 - 486 2020-12-30

Can neutrophil-lymphocyte ratio and platelet-lymphocyte ratio be related with skeletal mass area in COPD patients with acute exacerbation?

Sibel YURT [1] , Lale TUNA [2] , Halit ÇINARKA [3] , Mehmet TOPTAŞ [4] , Kemal KARAPINAR [5] , Gamze KIRKIL [6]


Introduction:This study was designed to assess whether there is a relation between inflammatory biomarkers such as NLR, PLR and psoas muscle area (PMA) as a marker of sarcopenia in COPD pateints who admitted to the emergency department of our clinic. Method: Retrospectivly one hundred forty three COPD patients who had CT scan for any reason during hospital admission were included. Patient characteristics and clinical and laboratory data were evaluated retrospectively. Results:In our study, we performed the correlations between NLR, PLR and CRP, FEV1, FVC, FEV1/FVC, right PMA, left PMA, total PMA. NLR and PLR were positively correlated with CRP (r=0.60, p<0.001, r=0.37, p<0.001, respectively), and no correlation was observed between NLR, PLR, CRP and all PMA values. However, there was a positive correlation between all PMA values and FEV1, FEV1/FVC parameters. There was no correlation between sarcopenia and emergency admission frequency and mortality. Conclusion NLR, and PLR may have a role as a biomarker of inflammation in COPD and its exacerbation. Sarcopenia is an expected finding in COPD patients, but relation between sarcopenia and inflammation requires further investigation.
Neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, COPD, Sarcopenia
  • Referans 1.4. Hwang JA, Kim YS, Leem AY, et al. Clinical implications of sarcopenia on decreased bone density in men with COPD. Chest 2017; 151: 1018-1027.
  • Referans 2. 10. Imtiaz F, Shafique K, Mirza SS, Ayoob Z, Vart P, Rao S. Neutrophil Lymphocyte Ratio as a Measure of Systemic Inflammation in Prevalent Chronic Diseases in Asian Population. Int Arch Med 2012; 5(1): 2.
Birincil Dil en
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Orjinal Araştırma
Yazarlar

Orcid: 0000-0002-7703-110X
Yazar: Sibel YURT (Sorumlu Yazar)
Kurum: UNIVERSITY OF HEALTH SCIENCES, ISTANBUL YEDIKULE CHEST DISEASE AND CHEST SURGERY EDUCATION AND RESEARCH HOSPITAL, DEPARTMENT OF PULMONOLOGY,
Ülke: Turkey


Orcid: 0000-0003-4409-3459
Yazar: Lale TUNA
Kurum: UNIVERSITY OF HEALTH SCIENCES, YEDIKULE CHEST DISEASE AND CHEST SURGERY EDUCATION AND RESEARCH HOSPITAL, DEPARTMENT OF RADIOLOGY
Ülke: Turkey


Orcid: 0000-0002-4910-149X
Yazar: Halit ÇINARKA
Kurum: UNIVERSITY OF HEALTH SCIENCES, ISTANBUL YEDIKULE CHEST DISEASE AND CHEST SURGERY EDUCATION AND RESEARCH HOSPITAL, DEPARTMENT OF PULMONOLOGY
Ülke: Turkey


Orcid: 0000-0002-3118-8793
Yazar: Mehmet TOPTAŞ
Kurum: UNIVERSITY OF HEALTH SCIENCES, ISTANBUL YEDIKULE CHEST DISEASE AND CHEST SURGERY EDUCATION AND RESEARCH HOSPITAL, DEPARTMENT OF ANESTHESIOLOGY
Ülke: Turkey


Orcid: 0000-0002-0035-5325
Yazar: Kemal KARAPINAR
Kurum: UNIVERSITY OF HEALTH SCIENCES, ISTANBUL YEDIKULE CHEST DISEASE AND CHEST SURGERY EDUCATION AND RESEARCH HOSPITAL, DEPARTMENT OF CHEST SURGERY
Ülke: Turkey


Orcid: 0000-0003-4799-5589
Yazar: Gamze KIRKIL
Kurum: FIRAT UNIVERSITY, FACULTY OF MEDICINE, PULMONOLOGY DEPARTMENT
Ülke: Turkey


Destekleyen Kurum yok
Proje Numarası yok
Tarihler

Kabul Tarihi : 11 Eylül 2020
Yayımlanma Tarihi : 30 Aralık 2020

AMA Yurt S , Tuna L , Çınarka H , Toptaş M , Karapınar K , Kırkıl G . Can neutrophil-lymphocyte ratio and platelet-lymphocyte ratio be related with skeletal mass area in COPD patients with acute exacerbation?. J Contemp Med. 2020; 10(4): 481-486.