Osteoartritli bireylerde vitamin D düzeyi ile ağrı, fonksiyonel durum ve yaşam kalitesi arasındaki ilişki

Yıl 2021, Cilt: 11 Sayı: 2, 180 - 184, 25.03.2021

Dilek Efe Arslan Nazan Kılıç Akça Sibel Şentürk Murat Korkmaz

https://doi.org/10.16899/jcm.845320

Öz

Amaç: Bu çalışma, osteoartritli (OA) bireylerde vitamin D düzeyi ile ağrı, fonksiyonel durum ve yaşam kalitesi arasındaki ilişkiyi belirlemek amacıyla yapılmıştır.
Gereç ve Yöntem: Kesitsel ve tanımlayıcı tipte olan bu çalışma 138 kişi ile 15 Nisan - 30 Ağustos 2019 tarihleri arasında, bir Araştırma ve Uygulama Hastanesi’nin ortopedi kliniğinde gerçekleştirildi.
Bulgular: Bireylerin% 70,3'ünün D vitamini düzeyi 20 ng / ml ve daha düşüktü. Bireylerin D vitamini düzeyleri ile yaş, VAS, WOMAC ve SF-36 alt ölçekleri arasında anlamlı bir ilişki olmadığı belirlendi (p> 0.05).
Sonuç: D vitamini OA'lı bireylerde çok yaygındır. Daha büyük örneklem büyüklüğüyle randomize kontrollü çalışmalar yapılması önerilebilir.

Anahtar Kelimeler

Osteoartrit, Vitamin D, Fonksiyonel Durum, Yaşam Kalitesi.

Destekleyen Kurum

yok

Proje Numarası

yok

Teşekkür

Çalışmaya katılan bütün hastalara teşekkür ederiz.

RELATIONSHIP BETWEEN VITAMIN D LEVEL ON PAIN, FUNCTIONAL STATUS AND QUALITY OF LIFE IN INDIVIDUALS WITH OSTEOARTHRITIS

Öz

Objective: This study was conducted to determine the correlation between vitamin D level and pain, functional status, and quality of life in individuals with osteoarthritis (OA).
Material and Method: This cross-sectional and descriptive study was completed with 138 individuals. The study was carried out between April 15 and August 30, 2019, at the Orthopedics Clinic of a Research and Practice Hospital.
Results: 70.3% of the individuals had a vitamin D level of 20 ng/ml and less. It was determined that there was no significant correlation between individuals' vitamin D levels and age, VAS, WOMAC, and SF-36 subscales (p>0.05).
Conclusion: Vitamin D deficiency (VDD) is very common in individuals with OA. It may be recommended to conduct randomized controlled studies with larger sample size.

Anahtar Kelimeler

Vitamin D, Osteoarthritis, Functional Status, Quality of Life

Proje Numarası

yok

Kaynakça

• 1.Vos T, Allen C, Arora M et al. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the global burden of disease study 2015. The Lancet 2016; 388:1545–602
• 2. Ovayolu N, Ovayolu Ö. editors. Basic internal medicine nursing and chronic diseases with different dimensions. Çukurova Nobel Publicaitons: Adana; 2016.
• 3. Ling SM, Rudolph K. Osteoarthritis, In: Clinical treatment in rheumatic diseases (3.Baskı), Dinç A. (Edt.), Özgün Ofset: Ankara; 127-132. 2007.
• 4. Arslan DE, Kutlutürkan S, Korkmaz M. The effect of aromatherapy massage on knee pain and functional status in participants with osteoarthritis. Pain Manag Nurs. 2019; 20:62-69
• 5. Çalışkan N. Superficial hot and cold application in the treatment of knee osteoarthritis: are the evidences enough? Contemporary Medicine Journal 2013; 3:136-43.
• 6.Cakar M. Association between vitamin D concentrations and knee pain in patients with osteoarthritis. Peer J. 2018; 6:e4670.
• 7. Park CY. Vitamin D in the prevention and treatment of osteoarthritis: from clinical interventions to cellular evidence. Nutrients. 2019; 11(2): 243.
• 8. McAlindon T, LaValley M, Schneider E et al. Effect of vitamin D supplementation on progression of knee pain and cartilage volume loss in patients with symptomatic osteoarthritis: A randomized controlled trial. J Am Med Assoc. 2013; 309:155162
• 9. Jin X, Antony B, Wang X et al. Effect of vitamin D supplementation on pain and physical function in patients with knee osteoarthritis (OA): An OA Trial Bank protocol for a systematic review and individual patient data (IPD) meta-analysis. BMJ open 2020; 10(4): e035302.
• 10.Zhang FF, Driban JB, Lo GH et al. Vitamin D deficiency is associated with progression of knee osteoarthritis. J Nutr 2014;144:2002–2008.
• 11. Yu Y, Liu D, Feng D, Zhao J. Association between vitamin D and knee osteoarthritis: a PRISMA-compliant meta-analysis. Zeitschrift für Orthopädie und Unfallchirurgie 2020.
• 12. Macfarlane GJ, Palmer B, Roy D, Afzal C, Silman AJ, O'Neill T. An excess of widespread pain among South Asians: are low levels of vitamin D implicated? Ann Rheum Dis 2005; 64:1217–1219.
• 13. Anand S, Kaysen GA, Chertow GM et al. Vitamin D deficiency, self-reported physical activity and health-related quality of life: the comprehensive dialysis study. Nephrol Dial Transplant 2011; 1–6.
• 14. Huang W, Shah S, Long Q, Crankshaw AK, Tangpricha V. Improvement of pain, sleep, and quality of life in chronic pain patients with vitamin D supplementation. Clin J Pain 2013; 29:341–347.
• 15. Alkan S, Sarsan A, Alkan H, Yıldız N, Topuz O, Ardıç F. Relatıonshıp between balance, physıcal performance and qualıty of lıfe wıth vıtamın d levels ın the elderly. Turkish J Geriatr 2012; 15:156-163
• 16. Kim HJ, Lee JY, Kim TJ, Lee JW. Association between serum vitamin D status and health-related quality of life (HRQOL) in an older Korean population with radiographic knee osteoarthritis: data from the Korean national health and nutrition examination survey (2010–2011). Health Qual Life Outcomes 2015; 13:4
• 17.Gallagher EJ, Liebman M, Bijur PE. Prospective validation of clinically important changes in pain severity measured on a visual analog scale. Ann Emerg Med 38:633-638.
• 18.Tüzün EH, Eker L, Aytar A. (2005) Acceptability, reliability, validity and responsiveness of the Turkish version of WOMAC osteoarthritis index. Osteoarthritis Cartilage 2001;13:28-33.
• 19. Aungst F, Aeschlimann A, Steiner W, Stucki G. Responsiveness of the WOMAC osteoarthritis index as compared with the SF-36 in patients with osteoarthritis of the legs undergoing a comprehensive rehabilitation intervention. Ann Rheum Dis 2001; 60:834-840.
• 20. Ware JE, Sheurborune CD. The MOS 36-item short-form health survey (SF-36). Med Care 1992;30:473-83.
• 21. Koçyiğit H, Aydemir Ö, Fişek G, Ölmez N. Reliability and Validity of the Turkish Version of Short Form-36 (SF-36) Drug and Therapy Journal 1999;12:102-6.
• 22. Çimen Atalar A. (2019) The Relationship Between 25 (OH) Vitamin D Level and the Severity of Disease and Sleep Quality in Restless Legs Syndrome. Turk J Neurol 25:87-91.
• 23. Fern L, Olazabal RM, Tovar KC, Alban NP, Wilman MV, Vilca JLR. Serum levels of vitamin D in women treated at rheumatology services in Lima Int. J Clin Rheumatol 2019; 14:105-112.
• 24. Goula T, Kouskoukis A, Drosos G et al. Vitamin D status in patients with knee or hip osteoarthritis in a Mediterranean country. J Orthop Traumatol 2015; 16:35-39.
• 25. Tu L, Zheng S, Cicuttini F et al. Effects of vitamin D supplementation on disabling foot pain in patients with symptomatic knee osteoarthritis. Arthritis Care & Research 2020 First published: 05 July 2020
• 26. Aksakoğlu G. Research and analysis in health. World of Medical Education 2006; 21:22-26.
• 27. Vaishya R, Vijay V, Lama P, Agarwal A. Does vitamin D deficiency influence the incidence and progression of knee osteoarthritis?–A literature review. Journal of clinical orthopaedics and trauma 2019; 10(1): 9-15.
• 28. Anari H, Enteshari-Moghaddam A, Abdolzadeh Y. Association between serum Vitamin D deficiency and Knee Osteoarthritis. Mediterranean Journal of Rheumatology 2019; 30(4).
• 29. Alkan SE, Çakıt BD, Salbaş E, Hakan G. The effects of vitamin D on muscle strength and functional status of the elderly patients with knee osteoarthritis. Aegean J Med Sci 2020; 3(2): 46-53.
• 30. Heidari B, Babaei M. Therapeutic and Preventive Potential of Vitamin D Supplementation in Knee Osteoarthritis. ACR Open Rheumatology 2019; 1(5): 318-326.
• 31. Alsowai S, Bin Bakr Z. (2018) Vitamin-D deficiency and insufficiency and quality of life in Jeddah, KSA: Is there any evidence of association. J Public Health Epidemiol 10:62-68.
• 32. Tuncer T, Çay HF, Kaçar C et al. Evidence-Based Recommendations for the Management of Knee Osteoarthritis:A Consensus Report of the Turkish League Against Rheumatism. Turk J Rheumatol 2012; (27): 1-17.
• 33.Dhesi JK, Jackson SH, Bearne LM, et al. Vitamin D supplementation improves neuromuscular function in older people who fall. Age Ageing 2014; 33:589-95.