Yıl 2021, Cilt 11 , Sayı 3, Sayfalar 288 - 293 2021-05-24

The Relationship Between Colorectal Cancer and Abdominal Adipose Tissue Distribution
Kolorektal Kanser ve Abdominal Yağ Doku Dağılımı Arasındaki İlişki

Fatma Esra BAHADIR ÜLGER [1] , Ümit AKYÜZ [2]


Aim: To examine the relationship between obesity and the subcutaneous, visceral and retroperitoneal adipose tissue thicknesses of the abdomen. Materials and Methods: The study included 62 control and 68 colorectal cancer patients. Abdominal computed tomography of the patients, which were taken within the last 6 months before preoperative or colonoscopic examination were evaluated. Colorectal cancer patients were divided into two groups as proximal and distal according to tumor localization. Subcutaneous, visceral and retroperitoneal adipose tissue thicknesses of the abdomen were measured using abdominal computed tomography scans. Results: There was no statistically significant difference between the colorectal cancer group and the control group in terms of body mass index, retroperitoneal and visceral adipose tissue thickness and gender (p=0.091; 0.246; 0.531; 0.190,respectively). The mean age of the colorectal cancer group was higher (p<0.001). The mean subcutaneous adipose tissue thickness of the control group was higher (p=0.045). There was no statistically significant difference between the proximal and distal colorectal cancer group in terms of age, retroperitoneal, subcutaneous and visceral adipose tissue thickness (p=0.734; 0.916; 0.800; 0.170, respectively). The mean body mass index of the group with distal mass was higher (p=0.028). The proportion of males was higher in the group with distal mass than in the group with proximal mass (p=0.024). Conclusion: In the risky population evaluating the adipose tissue in the abdomen and its distribution before the colorectal cancer is diagnosed or the symptoms develop will indicate which patients should be followed up in more detail and help to prevent more cases of colorectal cancer.
Amaç: Abdominal subkütan, viseral ve retroperitoneal yağ dokusu kalınlıkları ile obezite arasındaki ilişkiyi incelemek. Materyal ve Metod: Çalışmaya 62 kontrol ve 68 kolorektal kanser hastası dahil edildi. Hastaların ameliyat öncesi veya kolonoskopik muayenesinden önceki son 6 ay içinde çekilen abdominal bilgisayarlı tomografi tetkikleri değerlendirildi. Kolorektal kanser hastaları tümör lokalizasyonuna göre proksimal ve distal olarak iki gruba ayrıldı. Abdomenin subkütan, viseral ve retroperitoneal yağ doku kalınlıkları abdominal bilgisayarlı tomografi tetkikleri kullanılarak ölçüldü. Bulgular: Kolorektal kanser grubu ile kontrol grubu arasında vücut kitle indeksi, retroperitoneal ve viseral yağ doku kalınlığı ve cinsiyet açısından istatistiksel olarak anlamlı bir fark yoktu (sırasıyla p = 0.091; 0.246; 0.531; 0.190). Kolorektal kanser grubunun yaş ortalaması daha yüksekti (p <0.001). Kontrol grubunun ortalama subkütan yağ doku kalınlığı daha yüksekti (p = 0.045). Proksimal ve distal kolorektal kanser grubu arasında yaş, retroperitoneal, subkütan ve viseral yağ doku kalınlığı açısından istatistiksel olarak anlamlı bir fark yoktu (sırasıyla p = 0.734; 0.916; 0.800; 0.170). Distal kitle olan grubun ortalama vücut kitle indeksi daha yüksekti (p = 0.028). Distal kitle olan grupta erkeklerin oranı proksimal kitlesi olan gruba göre daha yüksekti (p = 0,024). Sonuç: Riskli popülasyonda kolorektal kanser teşhisi konmadan veya semptomlar gelişmeden önce abdomendeki yağ dokusunu ve dağılımını değerlendirmek, hangi hastaların daha detaylı izlenmesi gerektiğini gösterecek ve daha fazla kolorektal kanser vakasının oluşumunu önlemeye yardımcı olacaktır.
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Birincil Dil en
Konular Sağlık Bilimleri ve Hizmetleri
Bölüm Orjinal Araştırma
Yazarlar

Orcid: 0000-0002-2431-1757
Yazar: Fatma Esra BAHADIR ÜLGER (Sorumlu Yazar)
Kurum: İSTANBUL FATİH SULTAN MEHMET EĞİTİM ARAŞTIRMA HASTANESİ
Ülke: Turkey


Yazar: Ümit AKYÜZ
Kurum: SAĞLIK BİLİMLERİ ÜNİVERSİTESİ, İSTANBUL FATİH SULTAN MEHMET SAĞLIK UYGULAMA VE ARAŞTIRMA MERKEZİ
Ülke: Turkey


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Kabul Tarihi : 21 Şubat 2021
Yayımlanma Tarihi : 24 Mayıs 2021

AMA Bahadır Ülger F , Akyüz Ü . The Relationship Between Colorectal Cancer and Abdominal Adipose Tissue Distribution. J Contemp Med. 2021; 11(3): 288-293.