Evaluation of the COVID-19 Fear and Quality of Life in Patients with Inflammatory Bowel Disease During the Pandemic

Yıl 2022, Cilt: 12 Sayı: 2, 171 - 176, 15.03.2022

Rasim Eren Cankurtaran Öykü Tayfur Yürekli Naciye Şemnur Büyükaşık Osman Ersoy

https://doi.org/10.16899/jcm.989658

Öz

Aim: Novel Coronavirus disease (COVİD-19) pandemic had caused various problems in follow up and treatment of many chronic diseases such as Inflammatory Bowel Diseases (IBD). This study aimed to determine the level of fear and anxiety of COVID-19 and evaluate the quality of life of patients with IBD during the pandemic.
Materials and Methods: This study was conducted as a cross-sectional study, and a total of 150 participants (IBD patient group=75, control group=75) were included. In order to evaluate the level of COVID-19 fear and anxiety, the Fear of COVID-19 Scale (FCV-19S) and Coronavirus Anxiety Scale (CAS) were used. In addition, Short Form-36 (SF-36) test was used to evaluate health-related quality of life.
Results: FCV-19S and CAS scores were significantly higher in IBD patients compared to the control group. (p<0.05). In IBD patients some subscores of SF-36 were significantly lower than the control group (p<0.05). Univariate regression analyses showed that university degree of education, having Crohn’s disease, and using anti-TNF drugs were significantly correlated with the high level COVID-19 fear (p<0.05). FCV-19S results were found to be negatively correlated with emotional role limitation, energy, and mental health subscores of SF-36 in patients with IBD (p<0.05).
Conclusion: This study showed that IBD patients had higher levels of fear and anxiety regarding COVID-19. Increased levels of fear and anxiety decreased quality of life specifically mentally. One should keep in mind that the probability of nonadherence to drugs in patients with IBD during the pandemic and psychiatric support should be provided if necessary.

Anahtar Kelimeler

COVID-19, inflammatory bowel diseases, anxiety, pandemic, anti-TNF

Pandemi döneminde inflamatuvar barsak hastalığı olan hastalarda COVİD-19 korkusu ve yaşam kalitesinin değerlendirilmesi

Öz

Amaç: Yeni koronavirüs hastalığı (COVİD-19) pandemisi, İnflamatuvar Barsak Hastalıkları (İBH) gibi birçok kronik hastalığın takip ve tedavisinde çeşitli sorunlara neden olmuştur. Bu çalışma pandemi döneminde İBH’lı hastaların COVİD-19 korku ve anksiyete düzeylerini ve hayat kalitelerini değerlendirmeyi amaçladı.
Gereç ve yöntem: Bu çalışma kesitsel bir çalışma olarak yapılmış ve toplamda 150 hasta (İBH hasta grubu=75, kontrol grubu=75) çalışmaya dahil edilmiştir. COVİD-19 korku ve anksiyete seviyelerini değerlendirmek için COVİD-19 korku skalası (FCV-19S) ve koronavirüs anksiyete skalası (CAS) kullanıldı. Ayrıca sağlıkla ilgili yaşam kalitesini değerlendirmek için kısa form-36 (SF-36) testi kullanıldı.
Bulgular: İBH hastalarında kontrol grubuna göre FCV-19S ve CAS puanları anlamlı olarak daha yüksek, SF-36’nın bazı alt parametreleri anlamlı olarak daha düşük bulundu (p<0.05). Univaryant regresyon analizinde üniversite mezunu olmak, Crohn hastalığı tanılı olmak ve anti-TNF ilaç kullanmak yüksek COVİD-19 korkusuyla anlamlı olarak ilişkili olduğu saptandı (p<0.05). İBH hastalarında FCV-19S puanları ile SF-36’nın emosyonel rol kısıtlaması, enerji ve mental sağlık parametreleri arasında negatif korelasyon olduğu görüldü (p<0.05).
Sonuç: Bu çalışma İBH hastalarının COVİD-19 ile ilgili daha yüksek korku ve anksiyete seviyesine sahip olduğunu gösterdi. Artan korku ve anksiyete seviyeleri özellikle mental olarak yaşam kalitesini düşürmüştür. Bu dönemde İBH’lı hastalarda ilaç uyumsuzluğu olabileceği akılda tutulmalı ve gerekirse bu hastalara psikiyatrik destek sağlanmalıdır.

Anahtar Kelimeler

COVİD-19, inflamatuvar barsak hastalıkları, anksiyete, pandemi, anti-TNF

Kaynakça

• Referans1) World Health Organization website. https://www.who.int/ (accessed 11th April 2020)
• Referans2) Dubey S, Biswas P, Ghosh R et al. Psychosocial impact of COVID-19. Diabetes Metab Syndr 2020; 14 (5): 779-788.
• Referans3) Xiong J, Lipsitz O, Nasri F et al. Impact of COVID-19 pandemic on mental health in the general population: A systematic review. J Affect Disord 2020; 277: 55-64.
• Referans4) Sun L, Sun Z, Wu L et al. Prevalence and risk factors of acute posttraumatic stress symptoms during the COVID-19 outbreak in Wuhan, China. MedRxiv 2020; 1-17.
• Referans5) Cankurtaran D, Tezel N, Ercan B, Yildiz SY, Akyuz EU. The effects of COVID-19 fear and anxiety on symptom severity, sleep quality, and mood in patients with fibromyalgia: a pilot study. Advances in Rheumatology 2021; 61(1): 41.
• Referans6) Yang X, Yu Y, Xu J et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir Med 2020; 8 (5): 475-481.
• Referans7) Jeong DY, Kim S, Son MJ et al. Induction and maintenance treatment of inflammatory bowel disease: A comprehensive review. Autoimmunity Reviews 2019; 18(5): 439-454.
• Referans8) Cholapranee A, Hazlewood GS, Kaplan GG, Peyrin-Biroulet, Ananthakrishnan AN. Systematic review with meta‐analysis: comparative efficacy of biologics for induction and maintenance of mucosal healing in Crohn's disease and ulcerative colitis controlled trials. Alimentary pharmacology & therapeutics 2017; 45(10): 1291-1302.
• Referans9) Kennedy NA, Jones GR, Lamb CA et al. British Society of Gastroenterology guidance for management of inflammatory bowel disease during the COVID-19 pandemic. Gut 2020; 69(6): 984-990.
• Referans10) Trindade IA, Nuno BF. COVID-19 Pandemic’s effects on disease and psychological outcomes of people with inflammatory bowel disease in Portugal: a preliminary research. Inflammatory bowel diseases 2020.
• Referans11) Rubin DT, Feuerstein JD, Wang AY, Cohen RD. AGA clinical practice update on management of inflammatory bowel disease during the COVID-19 pandemic: expert commentary. Gastroenterology 2020; 159(1): 350-357.
• Referans12) Goodsall TM, Han S, Bryant RV. Understanding attitudes, concerns, and health behaviors of patients with inflammatory bowel disease during the coronavirus disease 2019 pandemic. Journal of gastroenterology and hepatology 2021; 36 (6): 1550-1555.
• Referans13) Ahorsu DK, Lin CY, Imani V, Saffari M, Griffiths MD, Pakpour AH. The Fear of COVID-19 Scale: Development and Initial Validation. Int J Ment Health Addict 2020; 1-9.
• Referans14) Satici B, Gocet-Tekin E, Deniz ME, Satici SA. Adaptation of the Fear of COVID-19 Scale: Its Association with Psychological Distress and Life Satisfaction in Turkey. Int J Ment Health Addict 2020; 1-9.
• Referans15) Nikopoulou VA, Holeva V, Parlapani E et al. Mental Health Screening for COVID-19: a Proposed Cutoff Score for the Greek Version of the Fear of COVID-19 Scale (FCV-19S). Int J Ment Health Addict 2020; 1-14.
• Referans16) Lee SA. Coronavirus Anxiety Scale: A brief mental health screener for COVID-19 related anxiety. Death Stud 2020; 44 (7): 393-401.
• Referans17) Evren C, Evren B, Dalbudak E, Topcu M, Kutlu N. Measuring anxiety related to COVID-19: A Turkish validation study of the Coronavirus Anxiety Scale. Death Stud 2020; 1-7.
• Referans18) Kocyigit H. Reliability and validity of the Turkish version of short form-36 (SF-36): a study in a group of patients will rheumatic diseases. Turk J Drugs Ther 1999; 12: 102-106.
• Referans19) Mıkocka-Walus A, Knowles SR, Keefer L, Graff L. Controversies revisited: a systematic review of the comorbidity of depression and anxiety with inflammatory bowel diseases. Inflammatory bowel diseases 2016; 22(3): 752-762.
• Referans20) Knowles SR, Graff LA, Wilding H, Hewitt C, Keefer L, Mıkocka-Walus A. Quality of life in inflammatory bowel disease: a systematic review and meta-analyses—part I. Inflammatory bowel diseases 2018; 24(4): 742-751.
• Referans21) Martínez-Lorca M, Martinez-Lorca A, Alvarez JJC, Armesilla MDC, Latorre JM. The fear of COVID-19 scale: Validation in spanish university students. Psychiatry research 2020; 113350.
• Referans22) Haase AM, Thorsgaard N, Lødrup AB. Medical treatment and COVID-19 related worries in patients with inflammatory bowel disease. Danish Medical Journal 2021; 68: 3.
• Referans23) Feıtosa MR, Parra RS, de Camargo HP et al. COVID-19 quarantine measures are associated with negative social impacts and compromised follow-up care in patients with inflammatory bowel disease in Brazil. Annals of gastroenterology 2021; 34(1): 39-45.