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Acute Dystonia Due to Pregabalin Abuse in an Adolescent

Cilt: 14 Sayı: 3 13 Kasım 2023
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Acute Dystonia Due to Pregabalin Abuse in an Adolescent

Öz

Pregabalin is a drug used to treat neuropathic pain, epilepsy, and fibromyalgia. However, the number of reported cases of pregabalin abuse is steadily growing. This case showed dystonia, an effect not previously documented as a consequence of pregabalin administration. A 16-year-old male patient with no known pre-existing medical conditions was admitted to the pediatric emergency department for the first time, complaining of drowsiness caused by pregabalin abuse. During the patient's follow-up, dystonia was observed, and biperiden was administered at a repeating dose. Subsequently, he was moved to the pediatric intensive care unit (PICU) for further tests and treatment. After three days of follow-up, the patient was discharged due to the absence of complaints. This case report presents dystonia resulting from pregabalin abuse, a condition that has not previously been documented in the literature.

Anahtar Kelimeler

Destekleyen Kurum

none

Kaynakça

  1. Verma V, Singh N, Singh Jaggi A. Pregabalin in neuropathic pain: evidences and possible mechanisms. Curr Neuropharmacol. 2014 Jan;12(1):44-56.
  2. Kuhn D, Müller TJ, Mutschler J. Pregabalinmissbrauch und -Abhängigkeit in verschiedenen europäischen Ländern im Hinblick auf deren Substitutionspolitik [Pregabalin abuse and dependence in various European countries: Association with substitution policies]. Fortschr Neurol Psychiatr. 2021 Nov;89(11):553-561.
  3. Rietjens SJ, Sikma MA, Hunault CC, de Lange DW, Hondebrink L. Pregabalin poisoning: Evaluation of dose-toxicity relationship. Br J Clin Pharmacol. 2022 Mar;88(3):1288-1297).
  4. Alles SRA, Cain SM, Snutch TP. Pregabalin as a Pain Therapeutic: Beyond Calcium Channels. Front Cell Neurosci. 2020 Apr 15;14:83.
  5. Evoy KE, Morrison MD, Saklad SR. Abuse and Misuse of Pregabalin and Gabapentin. Drugs. 2017 Mar;77(4):403-426.
  6. Isoardi, KZ, Polkinghorne, G, Harris, K, Isbister, GK. Pregabalin poisoning and rising recreational use: a retrospective observational series. Br J Clin Pharmacol. 2020; 86: 2435– 2440.
  7. Alan BE, Kızılkan MP, Akgül S. Pregabalin abuse in adolescence: a case series. Turk J Pediatr. 2022;64(2):357-363.
  8. Al-Husseini A, Wazaify M, Van Hout MC. Pregabalin Misuse and Abuse in Jordan: a Qualitative Study of User Experiences. Int J Ment Health Addict. 2018;16(3):642-654.

Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri

Bölüm

Olgu Sunumu

Yayımlanma Tarihi

13 Kasım 2023

Gönderilme Tarihi

18 Şubat 2023

Kabul Tarihi

20 Haziran 2023

Yayımlandığı Sayı

Yıl 2023 Cilt: 14 Sayı: 3

Kaynak Göster

APA
Çay, E., Türker, İ., Ekinci, F., Bilen, S., Ozgur Horoz, O., Yılmaz, H., & Yıldızdaş, D. (2023). Acute Dystonia Due to Pregabalin Abuse in an Adolescent. Journal of Emergency Medicine Case Reports, 14(3), 52-53. https://doi.org/10.33706/jemcr.1252728
AMA
1.Çay E, Türker İ, Ekinci F, vd. Acute Dystonia Due to Pregabalin Abuse in an Adolescent. Journal of Emergency Medicine Case Reports. 2023;14(3):52-53. doi:10.33706/jemcr.1252728
Chicago
Çay, Ezgi, İkbal Türker, Faruk Ekinci, vd. 2023. “Acute Dystonia Due to Pregabalin Abuse in an Adolescent”. Journal of Emergency Medicine Case Reports 14 (3): 52-53. https://doi.org/10.33706/jemcr.1252728.
EndNote
Çay E, Türker İ, Ekinci F, Bilen S, Ozgur Horoz O, Yılmaz H, Yıldızdaş D (01 Kasım 2023) Acute Dystonia Due to Pregabalin Abuse in an Adolescent. Journal of Emergency Medicine Case Reports 14 3 52–53.
IEEE
[1]E. Çay vd., “Acute Dystonia Due to Pregabalin Abuse in an Adolescent”, Journal of Emergency Medicine Case Reports, c. 14, sy 3, ss. 52–53, Kas. 2023, doi: 10.33706/jemcr.1252728.
ISNAD
Çay, Ezgi - Türker, İkbal - Ekinci, Faruk - Bilen, Sevcan - Ozgur Horoz, Ozden - Yılmaz, Hayri - Yıldızdaş, Dinçer. “Acute Dystonia Due to Pregabalin Abuse in an Adolescent”. Journal of Emergency Medicine Case Reports 14/3 (01 Kasım 2023): 52-53. https://doi.org/10.33706/jemcr.1252728.
JAMA
1.Çay E, Türker İ, Ekinci F, Bilen S, Ozgur Horoz O, Yılmaz H, Yıldızdaş D. Acute Dystonia Due to Pregabalin Abuse in an Adolescent. Journal of Emergency Medicine Case Reports. 2023;14:52–53.
MLA
Çay, Ezgi, vd. “Acute Dystonia Due to Pregabalin Abuse in an Adolescent”. Journal of Emergency Medicine Case Reports, c. 14, sy 3, Kasım 2023, ss. 52-53, doi:10.33706/jemcr.1252728.
Vancouver
1.Ezgi Çay, İkbal Türker, Faruk Ekinci, Sevcan Bilen, Ozden Ozgur Horoz, Hayri Yılmaz, Dinçer Yıldızdaş. Acute Dystonia Due to Pregabalin Abuse in an Adolescent. Journal of Emergency Medicine Case Reports. 01 Kasım 2023;14(3):52-3. doi:10.33706/jemcr.1252728

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