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A Case of Pulmonary Embolism after to Receiving a Dose of Sildenafil

Yıl 2024, , 53 - 55, 28.06.2024
https://doi.org/10.33706/jemcr.1398042

Öz

Introduction: Several studies have posited the potential of PDE5Is to precipitate arterial and venous thrombotic or embolic incidents, albeit rare occurrences. The present investigation documents a case of pulmonary thromboembolism (PTE) in an elderly male patient, aged 81, following the consumption of sildenafil. Case Report: An 81-year-old male patient who was previously diagnosed with syncope was admitted to our Emergency Department. He reported symptoms of dyspnea and vertigo. Approximately two hours before admission, there was a history of accidentally ingesting a total dose of 100 milligrams of sildenafil. Conclusion: The occurrence of PTE after sildenafil administration in this case, albeit rare, underscores the significance of meticulous evaluation of medications during patient history-taking. This case report, the importance of thorough efforts to rule out the diagnosis of PTE and to address even the slightest suspicion.

Kaynakça

  • 1. Smith BP, Babos M. Sildenafil. 2023 Feb 14. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32644404.
  • 2. Pușcașu C, Zanfirescu A, Negreș S, Șeremet OC. ExploringtheMultifacetedPotential of Sildenafil in Medicine. Medicina. 2023; 59(12):2190. doi.org/10.3390/medicina59122190.
  • 3. Tsertsvadze A, Yazdi F, Fink HA, et al. Oral sildenafilcitrate (viagra) for erectile dysfunction: a systematic review and meta-analysis of harms. Urology 2009; 74:831.
  • 4. Feenstra J, van Drie-Pierik RJ, Lacle´ CF, Stricker BH. Acute myocardial infarction associated with sildenafil. Lancet. 1998; 352:957–8.
  • 5. Rufa A, Cerase A, Monti L, et al. Recurrent venous thrombosis including cerebral venoussinus thrombosis in a patient taking sildenafil for erectile dysfunction. J Neurol Sci. 2007;260:293–5.
  • 6. Schwarz ER, Kapur V, Rastogi S, Rosanio S. Theeffect of chronic phosphodiesterase-5 inhibitoruse on different organ systems. Int J ImpotRes 2007;19:139–48.
  • 7. Elsayed YMH. Sildenafil serious emergency presentations; starting with angina, myocardial infarctions, ventricular fibrillation, and ending with death; retrospective observational study (13-report cases). Acci Anesand Crit Care Open A Open J. 2019; I(1): 13-20
  • 8. Ekmekyapar M, Şahin L, Gürbüz Ş. Comparison of Auxiliary Diagnostic Methods in Pulmonary Embolism. MedRecords. 2021;3(3):204-209.
  • 9. Chen HC, Wang CS, Chuang SH, Wang CY. Pulmonary embolism after tadalafil ingestion. Pharm World Sci 2008;30:610-2.
  • 10. Tortum F, Gür A. Investigation of the relationship between the PaO2/FiO2 ratio and Wells score in patients diagnosed with acute pulmonary embolism. Ann Med Res. 2023;30(2):226–230.
  • 11. Kaya Z, Tuncez A, Tekinalp M, Karanfil M, Kayrak M, Özdemir K .Comprehensive Echocardiographic Evaluation In Acute Pulmonary Embolism.Selcuk Med J 2013;29(4): 172-176.
  • 12. Khandait H, Harkut P, Khandait V, Bang V. Acute pulmonary embolism: Diagnosis and management. Indian Heart J. 2023 Sep-Oct;75(5):335-342. doi: 10.1016/j.ihj.2023.05.007.
Yıl 2024, , 53 - 55, 28.06.2024
https://doi.org/10.33706/jemcr.1398042

Öz

Kaynakça

  • 1. Smith BP, Babos M. Sildenafil. 2023 Feb 14. In: StatPearls. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32644404.
  • 2. Pușcașu C, Zanfirescu A, Negreș S, Șeremet OC. ExploringtheMultifacetedPotential of Sildenafil in Medicine. Medicina. 2023; 59(12):2190. doi.org/10.3390/medicina59122190.
  • 3. Tsertsvadze A, Yazdi F, Fink HA, et al. Oral sildenafilcitrate (viagra) for erectile dysfunction: a systematic review and meta-analysis of harms. Urology 2009; 74:831.
  • 4. Feenstra J, van Drie-Pierik RJ, Lacle´ CF, Stricker BH. Acute myocardial infarction associated with sildenafil. Lancet. 1998; 352:957–8.
  • 5. Rufa A, Cerase A, Monti L, et al. Recurrent venous thrombosis including cerebral venoussinus thrombosis in a patient taking sildenafil for erectile dysfunction. J Neurol Sci. 2007;260:293–5.
  • 6. Schwarz ER, Kapur V, Rastogi S, Rosanio S. Theeffect of chronic phosphodiesterase-5 inhibitoruse on different organ systems. Int J ImpotRes 2007;19:139–48.
  • 7. Elsayed YMH. Sildenafil serious emergency presentations; starting with angina, myocardial infarctions, ventricular fibrillation, and ending with death; retrospective observational study (13-report cases). Acci Anesand Crit Care Open A Open J. 2019; I(1): 13-20
  • 8. Ekmekyapar M, Şahin L, Gürbüz Ş. Comparison of Auxiliary Diagnostic Methods in Pulmonary Embolism. MedRecords. 2021;3(3):204-209.
  • 9. Chen HC, Wang CS, Chuang SH, Wang CY. Pulmonary embolism after tadalafil ingestion. Pharm World Sci 2008;30:610-2.
  • 10. Tortum F, Gür A. Investigation of the relationship between the PaO2/FiO2 ratio and Wells score in patients diagnosed with acute pulmonary embolism. Ann Med Res. 2023;30(2):226–230.
  • 11. Kaya Z, Tuncez A, Tekinalp M, Karanfil M, Kayrak M, Özdemir K .Comprehensive Echocardiographic Evaluation In Acute Pulmonary Embolism.Selcuk Med J 2013;29(4): 172-176.
  • 12. Khandait H, Harkut P, Khandait V, Bang V. Acute pulmonary embolism: Diagnosis and management. Indian Heart J. 2023 Sep-Oct;75(5):335-342. doi: 10.1016/j.ihj.2023.05.007.
Toplam 12 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Acil Tıp
Bölüm Case Report
Yazarlar

Emin Fatih Vişneci 0000-0001-8050-4433

Tevhid Aydın 0000-0003-4109-6347

Fatih Cemal Tekin 0000-0001-8410-5552

Demet Acar 0009-0000-4748-4733

Yayımlanma Tarihi 28 Haziran 2024
Gönderilme Tarihi 30 Kasım 2023
Kabul Tarihi 5 Haziran 2024
Yayımlandığı Sayı Yıl 2024

Kaynak Göster

APA Vişneci, E. F., Aydın, T., Tekin, F. C., Acar, D. (2024). A Case of Pulmonary Embolism after to Receiving a Dose of Sildenafil. Journal of Emergency Medicine Case Reports, 15(2), 53-55. https://doi.org/10.33706/jemcr.1398042
AMA Vişneci EF, Aydın T, Tekin FC, Acar D. A Case of Pulmonary Embolism after to Receiving a Dose of Sildenafil. Journal of Emergency Medicine Case Reports. Haziran 2024;15(2):53-55. doi:10.33706/jemcr.1398042
Chicago Vişneci, Emin Fatih, Tevhid Aydın, Fatih Cemal Tekin, ve Demet Acar. “A Case of Pulmonary Embolism After to Receiving a Dose of Sildenafil”. Journal of Emergency Medicine Case Reports 15, sy. 2 (Haziran 2024): 53-55. https://doi.org/10.33706/jemcr.1398042.
EndNote Vişneci EF, Aydın T, Tekin FC, Acar D (01 Haziran 2024) A Case of Pulmonary Embolism after to Receiving a Dose of Sildenafil. Journal of Emergency Medicine Case Reports 15 2 53–55.
IEEE E. F. Vişneci, T. Aydın, F. C. Tekin, ve D. Acar, “A Case of Pulmonary Embolism after to Receiving a Dose of Sildenafil”, Journal of Emergency Medicine Case Reports, c. 15, sy. 2, ss. 53–55, 2024, doi: 10.33706/jemcr.1398042.
ISNAD Vişneci, Emin Fatih vd. “A Case of Pulmonary Embolism After to Receiving a Dose of Sildenafil”. Journal of Emergency Medicine Case Reports 15/2 (Haziran 2024), 53-55. https://doi.org/10.33706/jemcr.1398042.
JAMA Vişneci EF, Aydın T, Tekin FC, Acar D. A Case of Pulmonary Embolism after to Receiving a Dose of Sildenafil. Journal of Emergency Medicine Case Reports. 2024;15:53–55.
MLA Vişneci, Emin Fatih vd. “A Case of Pulmonary Embolism After to Receiving a Dose of Sildenafil”. Journal of Emergency Medicine Case Reports, c. 15, sy. 2, 2024, ss. 53-55, doi:10.33706/jemcr.1398042.
Vancouver Vişneci EF, Aydın T, Tekin FC, Acar D. A Case of Pulmonary Embolism after to Receiving a Dose of Sildenafil. Journal of Emergency Medicine Case Reports. 2024;15(2):53-5.