EN
A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting
Öz
Introduction
Cyanosis along with altered mental should bring all the possible ethiologies into her mind in a minimum of time, based on the trauma, medical, environmental, and occupational history of the patient. Poisoning with methemoglobinemia inducing agents is one of the most important differentials especially when a history of occupational exposure to these agents is present.
Case Report
The patient, a 41-year-old healthy woman and engineer, experienced symptoms after exposure to aniline leading to dizziness and weakness, prompting a visit to the emergency department with cyanosis and low oxygen saturation. Initial vital signs showed decreased oxygen levels and elevated respiratory rate with normal ABG values despite ongoing cyanosis. Patient required intubation, mechanical ventilation, and was diagnosed with ARDS based on chest X-ray findings. Management included IV diuretics, 100% oxygen, and antioxidant treatment in the ICU. Despite treatment, oxygen saturation remained at 88% on the first day.
Conclusion
This case is a reminder of the importance of taking occupational history and management of aniline toxicity in a setting where methylene blue, the drug of choice for aniline toxicity, is not available in the drug stock.
Anahtar Kelimeler
Destekleyen Kurum
Not applicable.
Etik Beyan
Ethical approval is not required since our patient's treatment was based on approved options, and it was not found to be controversial, according to the Ethics Committee of our institution (Iran National Committee for Ethics in Biomedical Research).
Teşekkür
Not applicable.
Kaynakça
- 1. Uter W, Stropp G, Schnuch A, Lessmann H. Aniline—A ‘Historical’Contact Allergen? Current Data from the IVDK and Review of the Literature. The Annals of Occupational Hygiene. 2007;51(2):219-26.
- 2. Wang Y, Gao H, Na X-L, Dong S-Y, Dong H-W, Yu J, et al. Aniline induces oxidative stress and apoptosis of primary cultured hepatocytes. International Journal of Environmental Research and Public Health. 2016;13(12):1188.
- 3. Acute Exposure Guideline Levels for Selected Airborne Chemicals: Volume 1. 2000 Available from: https://www.ncbi. nlm.nih.gov/books/NBK222410/.
- 4. Di Girolamo F, Campanella L, Samperi R, Bachi A. Mass spectrometric identification of hemoglobin modifications induced by nitrosobenzene. Ecotoxicology and Environmental Safety. 2009;72(5):1601-8.
- 5. Harrison J, Jollow D. Contribution of aniline metabolites to aniline-induced methemoglobinemia. Molecular pharmacology. 1987;32(3):423-31.
- 6. Fan X, Wang J, Soman KV, Ansari G, Khan MF. Aniline-induced nitrosative stress in rat spleen: proteomic identification of nitrated proteins. Toxicology and applied pharmacology. 2011;255(1):103-12.
- 7. Genkin S, Raschewskaja A. The Diagnosis of Chronic Anilin Poisoning. Zentralblatt fur Gewerbehygiene und Unfallverhutung. 1933;20:29-36.
- 8. LUBASH GD, PHILLIPS RE, SHIELDS JD, III, BONSNES RW. Acute Aniline Poisoning Treated By Hemodialysis: Report of a Case. Archives of Internal Medicine. 1964;114(4):530-2.
Ayrıntılar
Birincil Dil
İngilizce
Konular
Klinik Tıp Bilimleri (Diğer)
Bölüm
Olgu Sunumu
Yazarlar
Yayımlanma Tarihi
25 Aralık 2024
Gönderilme Tarihi
29 Haziran 2024
Kabul Tarihi
27 Eylül 2024
Yayımlandığı Sayı
Yıl 2024 Cilt: 15 Sayı: 4
APA
Niroomand, B., Mohammadzadeh, I., Rahimi, M., & Bijandi, M. (2024). A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting. Journal of Emergency Medicine Case Reports, 15(4), 96-99. https://doi.org/10.33706/jemcr.1506993
AMA
1.Niroomand B, Mohammadzadeh I, Rahimi M, Bijandi M. A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting. Journal of Emergency Medicine Case Reports. 2024;15(4):96-99. doi:10.33706/jemcr.1506993
Chicago
Niroomand, Behnaz, Ibrahim Mohammadzadeh, Mitra Rahimi, ve Mohsen Bijandi. 2024. “A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting”. Journal of Emergency Medicine Case Reports 15 (4): 96-99. https://doi.org/10.33706/jemcr.1506993.
EndNote
Niroomand B, Mohammadzadeh I, Rahimi M, Bijandi M (01 Aralık 2024) A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting. Journal of Emergency Medicine Case Reports 15 4 96–99.
IEEE
[1]B. Niroomand, I. Mohammadzadeh, M. Rahimi, ve M. Bijandi, “A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting”, Journal of Emergency Medicine Case Reports, c. 15, sy 4, ss. 96–99, Ara. 2024, doi: 10.33706/jemcr.1506993.
ISNAD
Niroomand, Behnaz - Mohammadzadeh, Ibrahim - Rahimi, Mitra - Bijandi, Mohsen. “A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting”. Journal of Emergency Medicine Case Reports 15/4 (01 Aralık 2024): 96-99. https://doi.org/10.33706/jemcr.1506993.
JAMA
1.Niroomand B, Mohammadzadeh I, Rahimi M, Bijandi M. A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting. Journal of Emergency Medicine Case Reports. 2024;15:96–99.
MLA
Niroomand, Behnaz, vd. “A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting”. Journal of Emergency Medicine Case Reports, c. 15, sy 4, Aralık 2024, ss. 96-99, doi:10.33706/jemcr.1506993.
Vancouver
1.Behnaz Niroomand, Ibrahim Mohammadzadeh, Mitra Rahimi, Mohsen Bijandi. A Rare Case of Occupational Aniline Poisoning: Management in a Limited-Facility Setting. Journal of Emergency Medicine Case Reports. 01 Aralık 2024;15(4):96-9. doi:10.33706/jemcr.1506993