Lead Ingestion in a Child: A Case Report

Öz

Introduction: Lead is a heavy metal capable of causing significant toxic effects in children during acute exposure. Accidental ingestion of lead-containing objects is a common cause of acute poisoning in the pediatric population. Acute lead exposure can manifest with a broad clinical spectrum, ranging from neurological and gastrointestinal symptoms to life-threatening complications. Case Report: This report presents the case of a 6-year-old boy who accidentally ingested a lead object. The patient presented to the emergency department approximately 20 minutes after the incident. His vital signs were stable, physical examination findings were unremarkable, and laboratory results were normal. An upright abdominal X-ray revealed an oval-shaped radiopaque object located in the duodenum. On the fourth day, the blood lead level was measured as 14 µg/dL, and no symptoms were observed. Conclusion: In conclusion, the rapid passage of the lead object through the gastrointestinal tract may have played a role in limiting toxicity. This case contributes to the literature regarding the management and clinical course of acute lead poisoning in children.

Anahtar Kelimeler

• lead ingestion poisoning
• acute lead
• childhood lead toxication

Kaynakça

1. 1. Ahamed M, Siddiqui MohdKJ. Environmental lead toxicity and nutritional factors. Clinical Nutrition. 2007;26(4):400-408. doi:10.1016/j.clnu.2007.03.010
2. 2. Needleman H. Lead Poisoning. Annu Rev Med. 2004;55(1):209-222. doi:10.1146/annurev.med.55.091902.103653
3. 3. Shannon M, Graef JW. Lead Intoxication in Children with Pervasive Developmental Disorders. Journal of Toxicology: Clinical Toxicology. 1996;34(2):177-181. doi:10.3109/15563659609013767
4. 4. Jacobs DE, Clickner RP, Zhou JY, et al. The prevalence of lead-based paint hazards in U.S. housing. Environ Health Perspect. 2002;110(10). doi:10.1289/ehp.021100599
5. 5. Browder AA, Joselow MM, Louria DB. The problem of lead poisoning. Medicine (Baltimore). 1973;52(2):121-139. doi:10.1097/00005792-197303000-00002
6. 6. Gordon JN, Taylor A, Bennett PN. Lead poisoning: case studies. Brit J Clinical Pharma. 2002;53(5):451-458. doi:10.1046/j.1365-2125.2002.01580.x
7. 7. Barber T, Jacyna M. Acute lead intoxication from medications purchased online presenting with recurrent abdominal pain and encephalopathy. J R Soc Med. 2011;104(3):120-123. doi:10.1258/jrsm.2010.100334
8. 8. Jouglard J, de Haro L, Arditti J, Cottin C. [A wine pitcher, cause of lead poisoning]. Presse Med. 1996;25(6):243-246.

9. 9. Štěpánek L, Nakládalová M, Klementa V, Ferenčíková V. Acute lead poisoning in an indoor firing range. Med Pr. 2020;71(3):375-379. doi:10.13075/mp.5893.00930
10. 10. Gopinath B, Kappagantu V, Mathew R, Jamshed N. Acute lead poisoning: a diagnostic challenge in the emergency department. BMJ Case Rep. 2021;14(1):e239740. doi:10.1136/bcr-2020-239740
11. 11. Berkowitz S, Tarrago R. Acute Brain Herniation From Lead Toxicity. Pediatrics. 2006;118(6):2548-2551. doi:10.1542/peds.2006-1733
12. 12. Corradi M, Goldoni M, Sabbadini F, Mutti A. [Acute lead poisoning: a singular case of hemolytic anemia and lead colic]. Med Lav. 2011;102(3):243-249.
13. 13. Barber T, Jacyna M. Acute lead intoxication from medications purchased online presenting with recurrent abdominal pain and encephalopathy. J R Soc Med. 2011;104(3):120-123. doi:10.1258/jrsm.2010.100334
14. 14. Offor SJ, Mbagwu HOC, Orisakwe OE. Lead Induced Hepato-renal Damage in Male Albino Rats and Effects of Activated Charcoal. Front Pharmacol. 2017;8. doi:10.3389/fphar.2017.00107
15. 15. Hon KL, Fung CK, Leung AK. Childhoodleadpoisoning: an overview. Hong Kong Med J. 2017 Dec;23(6):616-21. doi: 10.12809/hkmj176214. Epub 2017 Oct 13.