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A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care

Yıl 2025, Cilt: 16 Sayı: 4, 164 - 166, 31.12.2025

Öz

Descending necrotizing mediastinitis (DNM) is a rare but life-threatening clinical condition that arises when infections originating in the head and neck extend into the mediastinum. In this case, we evaluate a 41-year-old male patient without any known systemic illness who presented with dysphagia, facial swelling, and dyspnea approximately three weeks after a dental filling procedure. Imaging revealed air-containing collections in the parapharyngeal space and subcutaneous emphysema extending toward the mediastinum. Despite detailed counseling regarding the risks, the patient refused hospitalization and surgery recommended by a multidisciplinary team. Oral antibiotic therapy was initiated, and close outpatient monitoring was advised. The clinical course of this case highlights the rapidly progressive nature of DNM and the ethical complexities arising from treatment refusal. It underscores the potential for systemic spread of localized infections after dental procedures, emphasizing the importance of early diagnosis, thorough patient education, and close follow-up whenever possible

Kaynakça

  • 1. Marty-Ané CH, Berthet JP, Alric P, Pegis JD, Rouvière P, Mary H. Management of descending necrotizing mediastinitis: an aggressive treatment for an aggressive disease. Ann Thorac Surg. 1999;68(1):212-217.
  • 2. Prado-Calleros HM, Jiménez-Fuentes E, Jiménez-Escobar I. Descending necrotizing mediastinitis: Systematic review on its treatment in the last 6 years, 75 years after its description. Head Neck. 2016;38 Suppl 1:E2275-E2283.
  • 3. Brook I. Microbiology and management of deep facial infections and Lemierre syndrome. ORL J Otorhinolaryngol Relat Spec. 2003;65(2):117-120.
  • 4. Brook I. Microbiology and antimicrobial management of head and neck infections in children. Adv Pediatr. 2008;55:305-325.
  • 5. Sakamoto H, Aoki T, Kise Y, Watanabe D, Sasaki J. Descending necrotizing mediastinitis due to odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;89(4):412-419.
  • 6. Wang B, Gao BL, Xu GP, Xiang C. Images of deep neck space infection and the clinical significance. Acta Radiol. 2014;55(8):945-951.
  • 7. Wheatley MJ, Stirling MC, Kirsh MM, Gago O, Orringer MB. Descending necrotizing mediastinitis: transcervical drainage is not enough. Ann Thorac Surg. 1990;49(5):780-784.
  • 8. Zhao Z, Ma D, Xu Y et al. Surgical therapy and outcome of descending necrotizing mediastinitis in Chinese: a single-center series. Front Med (Lausanne). 2024;10:1337852.
  • 9. Republic of Türkiye Ministry of Health. Patient Rights Regulation [Internet]. Resmî Gazete, 01 Aug 1998, No. 23420. Available from: https://www.saglik.gov.tr/EN-15627/patientrights. html.Cited 2025 Jul 20.
  • 10. Palmer RB, Iserson KV. The critical patient who refuses treatment: an ethical dilemma. J Emerg Med. 1997;15(5):729-733.
  • 11. Al-Wathinani AM, Barten DG, Alsahli H, et al. The Right to Refuse: Understanding Healthcare Providers’ Perspectives on Patient Autonomy in Emergency Care. Healthcare (Basel). 2023;11(12):1756.

Sessiz İlerleyen Tehlike: Diş Tedavisi Sonrası Descending Nekrotizan Mediastinit ve Tedavi Reddiyle Sonuçlanan Bir Olgu

Yıl 2025, Cilt: 16 Sayı: 4, 164 - 166, 31.12.2025

Öz

Descending nekrotizan mediastinit (DNM), baş-boyun kaynaklı enfeksiyonların mediastene ilerlemesi sonucu gelişen nadir ancak yüksek mortaliteye sahip bir klinik tablodur. Bu olguda, 41 yaşında sistemik hastalığı bulunmayan bir erkek hastada, diş dolgusu işleminden yaklaşık üç hafta sonra gelişen yutma güçlüğü, yüz şişliği ve nefes darlığı şikâyetleri değerlendirilmiştir. Görüntüleme bulguları parafaringeal alanda hava içeren koleksiyonları ve mediastene doğru uzanım gösteren cilt altı amfizemi ortaya koymuştur. Klinik değerlendirme sonrası multidisipliner ekip tarafından acil cerrahi ve hastaneye yatış önerilmiş; ancak hasta, tüm riskler kendisine ayrıntılı biçimde anlatılmasına rağmen tedaviyi reddetmiştir. Oral antibiyotik tedavisi başlanarak yakın takip önerilmiştir. Olgunun seyri, DNM’nin hızla ilerleyebilen doğasını ve tedavi reddi gibi etik açıdan tartışmalı durumların klinik sürece etkisini göstermesi bakımından dikkat çekicidir. Dental girişimler sonrası gelişen lokal enfeksiyonların sistemik yayılım gösterebileceği unutulmamalı; bu tür durumlarda erken tanı, kapsamlı bilgilendirme ve mümkünse yakın takip sağlanmalıdır.

Kaynakça

  • 1. Marty-Ané CH, Berthet JP, Alric P, Pegis JD, Rouvière P, Mary H. Management of descending necrotizing mediastinitis: an aggressive treatment for an aggressive disease. Ann Thorac Surg. 1999;68(1):212-217.
  • 2. Prado-Calleros HM, Jiménez-Fuentes E, Jiménez-Escobar I. Descending necrotizing mediastinitis: Systematic review on its treatment in the last 6 years, 75 years after its description. Head Neck. 2016;38 Suppl 1:E2275-E2283.
  • 3. Brook I. Microbiology and management of deep facial infections and Lemierre syndrome. ORL J Otorhinolaryngol Relat Spec. 2003;65(2):117-120.
  • 4. Brook I. Microbiology and antimicrobial management of head and neck infections in children. Adv Pediatr. 2008;55:305-325.
  • 5. Sakamoto H, Aoki T, Kise Y, Watanabe D, Sasaki J. Descending necrotizing mediastinitis due to odontogenic infections. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000;89(4):412-419.
  • 6. Wang B, Gao BL, Xu GP, Xiang C. Images of deep neck space infection and the clinical significance. Acta Radiol. 2014;55(8):945-951.
  • 7. Wheatley MJ, Stirling MC, Kirsh MM, Gago O, Orringer MB. Descending necrotizing mediastinitis: transcervical drainage is not enough. Ann Thorac Surg. 1990;49(5):780-784.
  • 8. Zhao Z, Ma D, Xu Y et al. Surgical therapy and outcome of descending necrotizing mediastinitis in Chinese: a single-center series. Front Med (Lausanne). 2024;10:1337852.
  • 9. Republic of Türkiye Ministry of Health. Patient Rights Regulation [Internet]. Resmî Gazete, 01 Aug 1998, No. 23420. Available from: https://www.saglik.gov.tr/EN-15627/patientrights. html.Cited 2025 Jul 20.
  • 10. Palmer RB, Iserson KV. The critical patient who refuses treatment: an ethical dilemma. J Emerg Med. 1997;15(5):729-733.
  • 11. Al-Wathinani AM, Barten DG, Alsahli H, et al. The Right to Refuse: Understanding Healthcare Providers’ Perspectives on Patient Autonomy in Emergency Care. Healthcare (Basel). 2023;11(12):1756.
Toplam 11 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Acil Tıp
Bölüm Olgu Sunumu
Yazarlar

İbrahim Halil Yasak 0000-0002-6399-7755

Duygu İclal Gerger 0009-0008-3838-726X

Gönderilme Tarihi 22 Temmuz 2025
Kabul Tarihi 19 Ekim 2025
Yayımlanma Tarihi 31 Aralık 2025
Yayımlandığı Sayı Yıl 2025 Cilt: 16 Sayı: 4

Kaynak Göster

APA Yasak, İ. H., & Gerger, D. İ. (2025). A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care. Journal of Emergency Medicine Case Reports, 16(4), 164-166. https://doi.org/10.33706/jemcr.1748268
AMA 1.Yasak İH, Gerger Dİ. A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care. Journal of Emergency Medicine Case Reports. 2025;16(4):164-166. doi:10.33706/jemcr.1748268
Chicago Yasak, İbrahim Halil, ve Duygu İclal Gerger. 2025. “A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care”. Journal of Emergency Medicine Case Reports 16 (4): 164-66. https://doi.org/10.33706/jemcr.1748268.
EndNote Yasak İH, Gerger Dİ (01 Aralık 2025) A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care. Journal of Emergency Medicine Case Reports 16 4 164–166.
IEEE [1]İ. H. Yasak ve D. İ. Gerger, “A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care”, Journal of Emergency Medicine Case Reports, c. 16, sy 4, ss. 164–166, Ara. 2025, doi: 10.33706/jemcr.1748268.
ISNAD Yasak, İbrahim Halil - Gerger, Duygu İclal. “A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care”. Journal of Emergency Medicine Case Reports 16/4 (01 Aralık 2025): 164-166. https://doi.org/10.33706/jemcr.1748268.
JAMA 1.Yasak İH, Gerger Dİ. A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care. Journal of Emergency Medicine Case Reports. 2025;16:164–166.
MLA Yasak, İbrahim Halil, ve Duygu İclal Gerger. “A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care”. Journal of Emergency Medicine Case Reports, c. 16, sy 4, Aralık 2025, ss. 164-6, doi:10.33706/jemcr.1748268.
Vancouver 1.Yasak İH, Gerger Dİ. A Silent Threat: A Case of Descending Necrotizing Mediastinitis Following Dental Treatment and Refusal of Medical Care. Journal of Emergency Medicine Case Reports [Internet]. 01 Aralık 2025;16(4):164-6. Erişim adresi: https://izlik.org/JA78JM69FL