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Fever-Induced Brugada Phenocopy: A Case Report

Cilt: 17 Sayı: 3 30 Eylül 2026
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Fever-Induced Brugada Phenocopy: A Case Report

Öz

Background: Brugada phenocopy (BrP) refers to reversible electrocardiographic (ECG) patterns that mimic Brugada syndrome (BrS) in the absence of an underlying congenital channelopathy. Fever is a recognized trigger that can unmask Brugada-like ECG changes, particularly in older adults. Case Report: An 83-year-old man presented to the emergency department with fever and respiratory symptoms. Initial ECG demonstrated a type 1 Brugada-like pattern. Laboratory evaluation revealed inflammatory markers consistent with infection. Following antipyretic treatment and normalization of body temperature, repeat ECG showed complete resolution of the Brugada-like changes. The patient was monitored in the cardiology unit without arrhythmic events. Conclusion: This case highlights fever as a reversible cause of Brugada phenocopy in an elderly patient. Prompt recognition and treatment of the underlying trigger are essential to avoid unnecessary invasive interventions such as implantable cardioverter-defibrillator implantation.

Anahtar Kelimeler

Destekleyen Kurum

None

Etik Beyan

None

Teşekkür

None

Kaynakça

  1. 1. Sarquella-Brugada G, Campuzano O, Arbelo E, Brugada J, Brugada R. Brugada syndrome: Clinical and genetic findings. Genetics in Medicine. 2016. https://doi.org/10.1038/gim.2015.35
  2. 2. Othieno AA, Isaacs DJ, Vinson DR, Levis JT. ECG Diagnosis: Brugada Syndrome. Permanente Journal. 2019. https://doi.org/10.7812/TPP/19.044
  3. 3. Veltmann C, Schimpf R, Echternach C, Eckardt L, Kuschyk J, Streitner F, et al. A prospective study on spontaneous fluctuations between diagnostic and non-diagnostic ECGs in Brugada syndrome: Implications for correct phenotyping and risk stratification. Eur Heart J. 2006;27. https://doi.org/10.1093/eurheartj/ehl205
  4. 4. Campuzano O, Sarquella-Brugada G, Cesar S, Arbelo E, Brugada J, Brugada R. Update on genetic basis of Brugada syndrome: Monogenic, polygenic or oligogenic? Int. J. Mol. Sci. 2020. https://doi.org/10.3390/ijms21197155
  5. 5. Adytia GJ, Sutanto H. Brugada phenocopy vs. Brugada syndrome: Delineating the differences for optimal diagnosis and management. Curr Probl Cardiol. 2024;49:102566. https://doi.org/10.1016/j.cpcardiol.2024.102566
  6. 6. Eckardt L, Veltmann C. More than 30 years of Brugada syndrome: a critical appraisal of achievements and open issues. Herzschrittmachertherapie und Elektrophysiologie. 2024;35. https://doi.org/10.1007/s00399-023-00983-y
  7. 7. Baranchuk A, Nguyen T, Ryu MH, Femenía F, Zareba W, Wilde AAM, et al. Brugada phenocopy: New terminology and proposed classification. Annals of Noninvasive Electrocardiology. 2012. https://doi.org/10.1111/j.1542-474X.2012.00525.x

Ayrıntılar

Birincil Dil

İngilizce

Konular

Acil Tıp

Bölüm

Olgu Sunumu

Yayımlanma Tarihi

30 Eylül 2026

Gönderilme Tarihi

17 Temmuz 2026

Kabul Tarihi

27 Temmuz 2026

Yayımlandığı Sayı

Yıl 2026 Cilt: 17 Sayı: 3

Kaynak Göster

APA
Ağaçkıran, M., Yağcı, S., Önder, S., & Ağaçkıran, İ. (2026). Fever-Induced Brugada Phenocopy: A Case Report. Journal of Emergency Medicine Case Reports, 17(3), 131-133. https://doi.org/10.33706/jemcr.1997271
AMA
1.Ağaçkıran M, Yağcı S, Önder S, Ağaçkıran İ. Fever-Induced Brugada Phenocopy: A Case Report. Journal of Emergency Medicine Case Reports. 2026;17(3):131-133. doi:10.33706/jemcr.1997271
Chicago
Ağaçkıran, Merve, Salih Yağcı, Sinan Önder, ve İlter Ağaçkıran. 2026. “Fever-Induced Brugada Phenocopy: A Case Report”. Journal of Emergency Medicine Case Reports 17 (3): 131-33. https://doi.org/10.33706/jemcr.1997271.
EndNote
Ağaçkıran M, Yağcı S, Önder S, Ağaçkıran İ (01 Eylül 2026) Fever-Induced Brugada Phenocopy: A Case Report. Journal of Emergency Medicine Case Reports 17 3 131–133.
IEEE
[1]M. Ağaçkıran, S. Yağcı, S. Önder, ve İ. Ağaçkıran, “Fever-Induced Brugada Phenocopy: A Case Report”, Journal of Emergency Medicine Case Reports, c. 17, sy 3, ss. 131–133, Eyl. 2026, doi: 10.33706/jemcr.1997271.
ISNAD
Ağaçkıran, Merve - Yağcı, Salih - Önder, Sinan - Ağaçkıran, İlter. “Fever-Induced Brugada Phenocopy: A Case Report”. Journal of Emergency Medicine Case Reports 17/3 (01 Eylül 2026): 131-133. https://doi.org/10.33706/jemcr.1997271.
JAMA
1.Ağaçkıran M, Yağcı S, Önder S, Ağaçkıran İ. Fever-Induced Brugada Phenocopy: A Case Report. Journal of Emergency Medicine Case Reports. 2026;17:131–133.
MLA
Ağaçkıran, Merve, vd. “Fever-Induced Brugada Phenocopy: A Case Report”. Journal of Emergency Medicine Case Reports, c. 17, sy 3, Eylül 2026, ss. 131-3, doi:10.33706/jemcr.1997271.
Vancouver
1.Merve Ağaçkıran, Salih Yağcı, Sinan Önder, İlter Ağaçkıran. Fever-Induced Brugada Phenocopy: A Case Report. Journal of Emergency Medicine Case Reports. 01 Eylül 2026;17(3):131-3. doi:10.33706/jemcr.1997271