Metil Alkol İntoksikasyonunda Beyin Manyetik Rezonans Görüntüleme Bulguları: Olgu Sunumu

Öz

Metil alkol toksik bir sıvı olup, endüstride antifriz, boya, cila gibi birçok ürünün yapısında bulunur. Toksik doz 20-250 ml olup beyin ve beyin sapı ödemi, putaminal nekroz gibi zehirlenme belirti ve bulguları en erken 12-24 saat sonra ortaya çıkar. Bu yazıda, manyetik rezonans görüntüleme yöntemiyle metil alkol intoksikasyonuna bağlı nadir görülen bazal gangliyonlarda kanama saptanan bir olgu sunulmaktadır.

Anahtar Kelimeler

• Metil alkol, intoksikasyon, manyetik rezonans görüntüleme, bazal gangliyon

Brain Magnetic Resonance Findings İn Methyl Alchol İntoxication: A Case Report

Öz

Methyl alcohol is a toxic liquid that is a present in industrial paint, polish and many other products. Its toxic dose is between 20-250 ml and intoxication sings andsymptoms as brain and brainstem edema and necrosis in putamen are observed early in 12-24 hours. In this article, we present a case report of a patient with a infrequint finding of hemorrhage in the basal gangliae in magnetic resonance imaging (MRI) due to methyl alcohol intoxication.

Anahtar Kelimeler

• Methyl alcohol, intoxication, magnetic resonance imaging, basal gangliae

Kaynakça

1. Berk WA, Henderson WV. Alcohols., In Tintinalli JE, Kelen GD, Stapczynski JS, editors, Emergency Medicine. A Comprehennsive Study Guide.5th ed. New York: McGraw Hill; 2000. p.1103-1109.
2. Naraqi S, Dethlefs RF, S lobodniuk RA, Sairere JS.An outbreak of acute methyl alcohol intoxication. Aust. N Z J Med 1979;9:65-68.
3. Yayci N, Ağritmiş H, Turla A, Koç S. Fatalities due to methyl al- cohol intoxication in Turkey: an 8 year study. Forensic Science İnternational 2003;131:36-41.
4. Yaycı N, İnanıcı MA. Metil Alkol (Metanol) Zehirlenmesi.Türkiye Klinikleri J Foren Med 2005; 2:101-108.
5. Elmas İ, Tüzün B,İmrağ C, Korkut M. Evaluation of deaths due to methyl alcohol intoxication with respect to forensic medicine. İstanbul Med. Faculty 1996;59(4):64-69.
6. Barceloux GD, Bond GR, Krenzelok EP, Cooper H, Vale JA. American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Methanol Poisoning. Clinical Toxicology, 2002;40(4):415-446.
7. Bennet JL, Jr.Cary, F.H.Mitchell G.L. Jr. Cooper M.N. Acute Methyl Alcohol Poisoning: A Review Based on Experiences in Outbreak 323 cases. Medicine 1953;32:431-463.
8. Blanco M, Casado R, Vazquez F, Pumar JM. CT and MR imag- ing findings in methanol intocication. AJNR Am J Neuroradiol 2006;27(2):452-4.

9. Server A,Hovda KE,Nakstad PH, Jacobsen D, Dullerud D, Haa- konsen M. Conventional and diffusion-weighted MRI in the evalu- ation of methanol poisoning. Acta Neurol 2003;44(6):691-5.
10. Halavaara J,Valanne L, setala K. Neuroimaging supports the clinical diagnosis of methanol poisoning. Neuroradiology 2002;44(11):924-8.
11. Phang P.T, PasseriniL, Mielke B, Berendet R, King EG. Brain hemorrhage associated with methanol poisoning. Crit.Care Med 1988;16:137-40.
12. Mittal B.V, Desai A.P, Khade K.R. Methyl alcohol poisoning an autopsy study of 28 cases. J. Post. Grad-Med 1997;37(1):9-13.