Guillain-Barre Sendromu Akut Motor Nöropati Varyantı Olgu Sunumu

Öz

Guillain-Barre Sendromu (GBS) immün aracılı periferal sinir myelin kılıf hasarı ile karakterize akut polinöropatidir. Rapor edilen ölüm oranı %2-5 arasında olmak ile birlikte hastaların %25’i solunumsal ve bulbar kasların tutulumuna bağlı olarak mekanik ventilatöre ihtiyaç duymaktadır. Klinik bulgular, lumbal ponksiyon ve/veya elektrotanısal testler ile desteklenerek GBS tanısı konur. GBS’dan şüphenilen hastaların yönetiminde ilk adım solunum fonksiyonunun değerlendirilmesi ve hava yolunun korunmasıdır. GBS tedavisinde IV immunglobülin (IVIG) ve plazmaferez kullanılmaktadır. Bu yazıda tipik klinik tablosu, elektrotanısal testler ile tanısı konan ve plazmeferez tedavisinden fayda gören bir GBS olgusu anlatılmaktadır.

Anahtar Kelimeler

• Akut inflamatuar nöropati, Guillain Barre Sendromu, periferik nöropati

Case Presentation of an Acute Motor Neuropathy Variant of Guillain-Barré Syndrome

Öz

Guillain-Barré Syndrome (GBS) is a type of acute polyneuropathy characterized by immune-mediated injury to the myelin sheath. The reported mortality rate varies between 2-5%, and 25% of patients require mechanical ventilation due to respiratory and bulbar muscle involvement. GBS can be diagnosed by clinical findings together with lumbar puncture and/or electrodiagnostic results. The first step in the management of patients with suspected GBS is an evaluation of respiratory function and protection of the airway. IV immunoglobulin and plasmapheresis have been used in the treatment of GBS. A case of GBS with typical history and physical findings supported by electrodiagnostic testing is described in this paper

Anahtar Kelimeler

• Acute inflammatory neuropathy, Guillain-Barré Syndrome, peripheral neuropathy

Kaynakça

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