Datura Stramonium Poisoning: Two Case Reports

Öz

Introduction: Datura stramonium is a wild plant, which grows in almost every region of Turkey and is found in the native flora. D. stramonium is used as a herbal medicine for asthma, bronchitis, eczema, and hemorrhoid treatment. Because of D. stramonium’s hallucinative and euphoric effects, it can be abused, particularly by drug addicts. Excessive oral intake may cause anticholinergic toxicity. In the case of a very high dose intake, it may result in coma. In this study, we have discussed two patients who presented to the emergency department of our hospital with anticholinergic findings and were diagnosed with D. stramonium intoxication.Case Report: Two patients presented to the emergency department of our hospital with signs and symptoms of anticholinergic poisoning. Two cases were also fell complaints with symptomatic treatment. Both the patients were admitted to the toxicology department and were followed-up for 2 days. The complaints regressed the next day, and the both the patients were discharged with complete recovery.Conclusion: Our study reporting the present cases shows that D. stramonium, which is used for therapeutic purposes, also causes severe intoxication. Therefore, wild plant poisoning should be considered for every patient presenting to the emergency department with unexplained anticholinergic symptoms and complaints

Anahtar Kelimeler

• Datura stramonium, anticholinergic, poisoning

Kaynakça

1. Koç H. The healthy living with plants.1st edition. Ankara, Ümit offset 2002; 147-8.
2. Uzun E, Sariyar G, Adsersen A, Karakoc B, Otük G, Oktayoğlu G, et al. Tra- ditional medicine in Sakarya province (Turkey) and antimicrobial activi- ties of selected species. J Ethnopharmacol 2004; 95: 287-96. [CrossRef]
3. Esendal E, Kevseroğlu K, Aytaç S, Özyazıcı G. Effects of Different Levels of Nitrogen on some Characters of Datura Collected from Samsun Envi- rons. Turk J Agric For 2000; 24: 333-9.
4. Kurzbaum A, Simsolo C, Kvasha L, Blum A. Toxic delirium due to Datura stramonium. Isr Med Assoc J 2001; 3: 538-9.
5. Steenkamp PA, Harding NM, van Heerden FR, van Wyk BE. Fatal Datura poisoning: identifycation of atropine and scopolamine by high perfor- mance liquid chromatography/photodiode array/mass spectrometry. Forensic Sci Int 2004; 145: 31-9. [CrossRef]
6. Parissis D, Mellidis C, Boutis A, Apostolidis K, Ignatiadis M, Kiosses V, et al. Neurological findings in a case of coma secondary 140 to Datura stramonium poisoning. Eur J Neurol 2003; 10: 745-6. [CrossRef]
7. Wiebe TH, Sigurdson ES, Katz LY. Angel’s Trumpet (Datura stramonium) poisoning and delirium inadolescents in Winnipeg, Manitoba: Summer 2006. Paediatr Child Health 2008; 13: 193-6.
8. Köse R, Şahin Ö.Ö, Abay E. A case of delirium due to datura stramonium intoxication. Anatolian Journal of Psychiatry 2008; 9: 54-7.

9. Rivera W, Velez LI. Rosen’s Emergency Medicine: Concepts and Clinical Practice. 6th ed. Philadelphia: Mosby Inc, 2006.
10. Wax PM, Young CA. Anticholinergic toxicity. In:Tintinalli JE, Kelen GD, Stapczynski JS editors. Emergency Medicine, 7th edition. New York: McGraw-Hill Co, 2011; 1305-8.