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Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use.

Cilt: 12 Sayı: 1 18 Mart 2021
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Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use.

Öz

İntroduction: Sildenafil is a phosphodiesterase 5 enzyme inhibitor used in the treatment of erectile dysfunction and pulmonary hypertension. The use of sildenafil with nitrates is well known to cause myocardial ischemia. However, patients with a history of hypotension, arrhythmia, previous myocardial infarction, or stroke should be given sildenafil carefully. A few cases have been reported in the literature related to ischemic stroke and transient ischemic attack due to sildenafil use. Case report: We report a case of middle cerebral artery (MCA) infarction after two tablets sildenafil in a 57-year-old male patient with no underlying disease. In the diffusion MRI (magnetic resonance imaging) imaging of the patient, acute diffusion limitation was observed in the left frontal lobe and parietal lobe starting from the centrum semiovale level and also in the MCA supply area affecting the medial section of the temporal lobe. We believe that this infarction is caused by the development of severe hypotension due to alcohol use with sildenafil. Conclusion: Not only availability of hypotension, history of MI and stroke, health care providers should also give attention prescribing sildenafil in the case of cigarette and alcohol use.

Anahtar Kelimeler

Kaynakça

  1. References 1) Zusman RM, Morales A, Glasser DB, Osterloh IH. Overall cardiovascular profile of sildenafil citrate. American Journal of Cardiology 1999; 83: 35C–44C
  2. 2) Zusman RM, Morales A, Glasser DB, Osterloh IH. Overall cardiovascular profile of sildenafil citrate. Am J Cardiol 1999;83:35C–44C.
  3. 3)Beavo JA. Cyclic nucleotide phosphodiesterase: functional implications of multiple isoforms. Physiological Reviews 1995; 75: 725–748
  4. 4)Cheitlin MD, Hutter AM Jr, Brindis RG, et al. Use of sildenafil (VIAGRA) in patients with cardiovascular disease: ACC/AHA expert consensus document. Circulation 1999;99:168–177. 5) Zusman RM, Morales A, Glasser DB, Osterloh IH. Overall cardiovascular profile of sildenafil citrate. Am J Cardiol 1999;83:35C–44C.
  5. 6)KimKK,KimDG,KuYHet al.Bilateralcerebral hemispheric infarction associated with sildenafil citrate (Viagra) use. Eur J Neurol 2008; 15:306–8.
  6. 7)Stefanovic-Budimkic M, Jovanovic DR, Beslac-Bumbasirevic L, Ercegovac MD. Recurrent ischemic stroke associated with sildenafil and tadalafil use in a young adult. Clin Neurol Neurosurg 2012; 114:405–7.
  7. 8)Morgan JC, Alhatou M, Oberlies J, Johnston KC. Transient ischemic attack and stroke associated with sildenafil (Viagra) use. Neurology 2001; 57:1730
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Ayrıntılar

Birincil Dil

İngilizce

Konular

Klinik Tıp Bilimleri

Bölüm

Olgu Sunumu

Yayımlanma Tarihi

18 Mart 2021

Gönderilme Tarihi

23 Kasım 2020

Kabul Tarihi

13 Ocak 2021

Yayımlandığı Sayı

Yıl 2021 Cilt: 12 Sayı: 1

Kaynak Göster

APA
Sipahioğlu, H., Bulut, K., & Esmaoğlu, A. (2021). Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use. Journal of Emergency Medicine Case Reports, 12(1), 25-27. https://doi.org/10.33706/jemcr.830139
AMA
1.Sipahioğlu H, Bulut K, Esmaoğlu A. Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use. Journal of Emergency Medicine Case Reports. 2021;12(1):25-27. doi:10.33706/jemcr.830139
Chicago
Sipahioğlu, Hilal, Kadir Bulut, ve Aliye Esmaoğlu. 2021. “Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use”. Journal of Emergency Medicine Case Reports 12 (1): 25-27. https://doi.org/10.33706/jemcr.830139.
EndNote
Sipahioğlu H, Bulut K, Esmaoğlu A (01 Mart 2021) Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use. Journal of Emergency Medicine Case Reports 12 1 25–27.
IEEE
[1]H. Sipahioğlu, K. Bulut, ve A. Esmaoğlu, “Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use”., Journal of Emergency Medicine Case Reports, c. 12, sy 1, ss. 25–27, Mar. 2021, doi: 10.33706/jemcr.830139.
ISNAD
Sipahioğlu, Hilal - Bulut, Kadir - Esmaoğlu, Aliye. “Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use”. Journal of Emergency Medicine Case Reports 12/1 (01 Mart 2021): 25-27. https://doi.org/10.33706/jemcr.830139.
JAMA
1.Sipahioğlu H, Bulut K, Esmaoğlu A. Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use. Journal of Emergency Medicine Case Reports. 2021;12:25–27.
MLA
Sipahioğlu, Hilal, vd. “Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use”. Journal of Emergency Medicine Case Reports, c. 12, sy 1, Mart 2021, ss. 25-27, doi:10.33706/jemcr.830139.
Vancouver
1.Hilal Sipahioğlu, Kadir Bulut, Aliye Esmaoğlu. Middle cerebral artery infarction associated with sildenafil citrate (Viagra) use. Journal of Emergency Medicine Case Reports. 01 Mart 2021;12(1):25-7. doi:10.33706/jemcr.830139

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