BibTex RIS Kaynak Göster

Medikal Abortus İçin Oral ve Vaginal Misoprostol Kullanımı

Yıl 2011, Cilt: 2 Sayı: 2, 32 - 34, 01.04.2011

Halil Kaya Özgür Söğüt Mehmet Tahir Gökdemir Mehmet Akif Dokuzoğlu

Öz

Misioprostol, sentetik bir PGE1 analoğu olup NSAİ ilaçların kronik
kullanımındaki gastrik yan etkilerini azaltmak amacıyla kullanılmaktadır.
Aynı zamanda gebelikte servikal dilatasyon için bir preindüksiyon ajanı
olarak da kullanılmaktadır. Ucuz ve kolay ulaşılabilir olan misoprostol yan
etki olarak uterin kontraksiyonlara neden olabilir. Bu yüzden istenmeyen
gebeliklerin sonlandırılmasında illegal olarak da kullanılmaktadır. Tekrarlayan
dozlarda oral ya da vajinal 800 mikrogram (mcg) misoprostol alımı
sonrasında %50 -90 oranında abortus meydana gelmektedir. Bu vaka sunumunda
abortus amaçlı yüksek dozda misoprostol (PGE1-Cytotec®) alımı
sonrası acil servise başvuran; ancak abortus oluşmayan bir olgu sunulmuştur.

Anahtar Kelimeler

Abortus Fetal Takip Kontrasepsiyon Misoprostol

Kaynakça

  • Ngai SW, Au Yeung KC, Lao T, Ho PC. Oral misoprostol versus vaginal gemeprost for cervical dilatation prior to vacuum aspiration in women sixth to twelveth week of ges- tation. Contraception 1995;51:347-50.
  • Gary Cunningham F, Norman F. Gant, Kenneth J. Leveno, Larry C. Gilstrap III, John C.Hayth, Katharine D. Wen- strom. İnduction and Augmentation of Labor; Williams Ob- stetrics 2001;469-481.
  • Adair CD, Weeks JW, Barrilleaux S, Edwards M, Burlison K, Lewis DF. Oral or vaginal misoprostol administration for induction of labor:A randomized, double-blind trial. Obstet Gynecol 1998;92:810.
  • Danielsson KG, Marions L, Rodriguez A, Spur BW, Wong PY, Bygdeman M. Comparison between oral and vaginal administration of misoprostol on uterine contractility. Ob- stet Gynecol 1999;93:275-80.
  • Sanchez-Ramos L, Kaunitz AM, Delke I. Labor induction with 25 microg versus 50 microg intravaginal misoprostol: a systematic review. Obstet Gynecol 2002;99:145-53.
  • El-Refaey H, Templeton A . Early induction of abortion by a combination of mifepristone and misoprostol administered by the vaginal route . Contraception 1994;49:111-4.
  • Carbonell JLL,Varela L, Valezco A,Tanda R. Vaginal mizo- prostol for abortion at10-13 weeks gestation. Eur J contrac Rep Health C 1999;4:35-40.
  • Özdemir A,Güralp H, Hızıroğlu S, Ertopçu K,Özdemir M, Haberal A. İkinci trimestır gebeliklerin sonlandırılmasında PGE–1 ve PGE–2 ‘nin karşılaştırılması. Jinekoloji Obstet- rik. 1999;9:169-74.
  • Shetty A, Danielian P, Templeton A. A comparison of oral and vaginal misoprostol tablets in induction of labour at term. BJOG 2001;108:238-43.
  • Wing DA, Rakall A, Jones MM, Goodwin TM, Paul RH. Misoprostol: An effective agent for cervical ripening and labor induction. Am J Obstet Gynecol. 1995;172:1811-6.
  • Fonseca W, Alencar AJC, Mota FSB, Coelho HLL. Miso- prostol and congenital malformations. Lancet 1991;338:56.
  • Creinin MD, Vittinghoff E, Keder L. Methotreksate and misoprostol for early abortion: a multicenter trial. I. Safety and efficacy. Contraception. 1996;53: 321-27.
  • Zieman M, Fong S.K, Benowitz N.L, Bankster D, Darney P.D. Absorbtion kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol 1997;90:88-92.
  • Costa SH, Vessey MP. Misoprostol and illegal abortion in Rio de Janeiro, Brazil. Lancet 1993: 15;1258-61.
  • El-Rafaey H, Rajasekar D, Abdalia M, Calder L, Templeton A. Induction of abortion with mifepristone and oral or vagi- nal misoprostol. N Eng J Med 1995;332:983-87.
  • Burnett MA, Corbett CA, Gertenstein RJ. A randomized trial of laminaria tents versus misoprostol for cervical rip- ening in first trimester surgical abortion. J Obstet Gynecol Can 2005;27:38-42.
  • Ozden S,Delikara MN,Avci A,Fıçıcıoğlu C, İntravajinal misoprostolvs.expectant management in premature rupture of membranes with low Bishop scores at taerm.Int J Gyne- col Obstet 2002;77:109-15.

Using Oral and Intravaginal Misoprostol For Medical Abortion

Yıl 2011, Cilt: 2 Sayı: 2, 32 - 34, 01.04.2011

Halil Kaya Özgür Söğüt Mehmet Tahir Gökdemir Mehmet Akif Dokuzoğlu

Öz

Misoprostol is a synthetic PGE1 derivate that is used to reduce gastric side effects of chronic NSAI drugs. It is also used as a pre-induction agent for cervical dilatation at delivery event. Misoprostol is cheap and easy receivable drug that causes uterine contractions as side effect. For this reason it is used to terminate unwanted pregnancies illegally. After repetitive oral or intravaginal usage of 800 microgram (mcg) misoprostol abortus happens at range of 50% 90%. This case report is about high dose misoprostol (PGE1-Cytotec®) intake and unsuccessful abortion

Anahtar Kelimeler

Abortion Fetal Monitoring Contraception Misoprostol.

Kaynakça

  • Ngai SW, Au Yeung KC, Lao T, Ho PC. Oral misoprostol versus vaginal gemeprost for cervical dilatation prior to vacuum aspiration in women sixth to twelveth week of ges- tation. Contraception 1995;51:347-50.
  • Gary Cunningham F, Norman F. Gant, Kenneth J. Leveno, Larry C. Gilstrap III, John C.Hayth, Katharine D. Wen- strom. İnduction and Augmentation of Labor; Williams Ob- stetrics 2001;469-481.
  • Adair CD, Weeks JW, Barrilleaux S, Edwards M, Burlison K, Lewis DF. Oral or vaginal misoprostol administration for induction of labor:A randomized, double-blind trial. Obstet Gynecol 1998;92:810.
  • Danielsson KG, Marions L, Rodriguez A, Spur BW, Wong PY, Bygdeman M. Comparison between oral and vaginal administration of misoprostol on uterine contractility. Ob- stet Gynecol 1999;93:275-80.
  • Sanchez-Ramos L, Kaunitz AM, Delke I. Labor induction with 25 microg versus 50 microg intravaginal misoprostol: a systematic review. Obstet Gynecol 2002;99:145-53.
  • El-Refaey H, Templeton A . Early induction of abortion by a combination of mifepristone and misoprostol administered by the vaginal route . Contraception 1994;49:111-4.
  • Carbonell JLL,Varela L, Valezco A,Tanda R. Vaginal mizo- prostol for abortion at10-13 weeks gestation. Eur J contrac Rep Health C 1999;4:35-40.
  • Özdemir A,Güralp H, Hızıroğlu S, Ertopçu K,Özdemir M, Haberal A. İkinci trimestır gebeliklerin sonlandırılmasında PGE–1 ve PGE–2 ‘nin karşılaştırılması. Jinekoloji Obstet- rik. 1999;9:169-74.
  • Shetty A, Danielian P, Templeton A. A comparison of oral and vaginal misoprostol tablets in induction of labour at term. BJOG 2001;108:238-43.
  • Wing DA, Rakall A, Jones MM, Goodwin TM, Paul RH. Misoprostol: An effective agent for cervical ripening and labor induction. Am J Obstet Gynecol. 1995;172:1811-6.
  • Fonseca W, Alencar AJC, Mota FSB, Coelho HLL. Miso- prostol and congenital malformations. Lancet 1991;338:56.
  • Creinin MD, Vittinghoff E, Keder L. Methotreksate and misoprostol for early abortion: a multicenter trial. I. Safety and efficacy. Contraception. 1996;53: 321-27.
  • Zieman M, Fong S.K, Benowitz N.L, Bankster D, Darney P.D. Absorbtion kinetics of misoprostol with oral or vaginal administration. Obstet Gynecol 1997;90:88-92.
  • Costa SH, Vessey MP. Misoprostol and illegal abortion in Rio de Janeiro, Brazil. Lancet 1993: 15;1258-61.
  • El-Rafaey H, Rajasekar D, Abdalia M, Calder L, Templeton A. Induction of abortion with mifepristone and oral or vagi- nal misoprostol. N Eng J Med 1995;332:983-87.
  • Burnett MA, Corbett CA, Gertenstein RJ. A randomized trial of laminaria tents versus misoprostol for cervical rip- ening in first trimester surgical abortion. J Obstet Gynecol Can 2005;27:38-42.
  • Ozden S,Delikara MN,Avci A,Fıçıcıoğlu C, İntravajinal misoprostolvs.expectant management in premature rupture of membranes with low Bishop scores at taerm.Int J Gyne- col Obstet 2002;77:109-15.
Toplam 17 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA43VF27DB
Bölüm Araştırma Makalesi
Yazarlar

Halil Kaya Bu kişi benim

Özgür Söğüt Bu kişi benim

Mehmet Tahir Gökdemir Bu kişi benim

Mehmet Akif Dokuzoğlu Bu kişi benim

Yayımlanma Tarihi 1 Nisan 2011
Gönderilme Tarihi 1 Nisan 2011
Yayımlandığı Sayı Yıl 2011 Cilt: 2 Sayı: 2

Kaynak Göster

APA Kaya, H., Söğüt, Ö., Gökdemir, M. T., Dokuzoğlu, M. A. (2011). Using Oral and Intravaginal Misoprostol For Medical Abortion. Journal of Emergency Medicine Case Reports, 2(2), 32-34.
AMA Kaya H, Söğüt Ö, Gökdemir MT, Dokuzoğlu MA. Using Oral and Intravaginal Misoprostol For Medical Abortion. Journal of Emergency Medicine Case Reports. Nisan 2011;2(2):32-34.
Chicago Kaya, Halil, Özgür Söğüt, Mehmet Tahir Gökdemir, ve Mehmet Akif Dokuzoğlu. “Using Oral and Intravaginal Misoprostol For Medical Abortion”. Journal of Emergency Medicine Case Reports 2, sy. 2 (Nisan 2011): 32-34.
EndNote Kaya H, Söğüt Ö, Gökdemir MT, Dokuzoğlu MA (01 Nisan 2011) Using Oral and Intravaginal Misoprostol For Medical Abortion. Journal of Emergency Medicine Case Reports 2 2 32–34.
IEEE H. Kaya, Ö. Söğüt, M. T. Gökdemir, ve M. A. Dokuzoğlu, “Using Oral and Intravaginal Misoprostol For Medical Abortion”, Journal of Emergency Medicine Case Reports, c. 2, sy. 2, ss. 32–34, 2011.
ISNAD Kaya, Halil vd. “Using Oral and Intravaginal Misoprostol For Medical Abortion”. Journal of Emergency Medicine Case Reports 2/2 (Nisan 2011), 32-34.
JAMA Kaya H, Söğüt Ö, Gökdemir MT, Dokuzoğlu MA. Using Oral and Intravaginal Misoprostol For Medical Abortion. Journal of Emergency Medicine Case Reports. 2011;2:32–34.
MLA Kaya, Halil vd. “Using Oral and Intravaginal Misoprostol For Medical Abortion”. Journal of Emergency Medicine Case Reports, c. 2, sy. 2, 2011, ss. 32-34.
Vancouver Kaya H, Söğüt Ö, Gökdemir MT, Dokuzoğlu MA. Using Oral and Intravaginal Misoprostol For Medical Abortion. Journal of Emergency Medicine Case Reports. 2011;2(2):32-4.