BibTex RIS Kaynak Göster

Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report

Yıl 2011, Cilt: 2 Sayı: 2, 47 - 49, 01.04.2011

Öz

Poisonings are constituted a substantial part of the emergency department. Combined use of antihypertensive drugs in the treatment of essential hypertension is common. Using of these drugs for suicide does not seen so common. One of these combined drugs which are used in clinic is Angiotension Converting Enzyme inhibitors and calcium channel blockers. Sinus bradycardia, severe hypotension an AV blocks can be seen due to excessive using of these drugs. More serious outcome may occur if these conditions do not treated immediately. In this study, we aim at discussing the case of 17-year-old patient in the light literature, who took 13 units of Tarka ® forte tablets (240 mg + 4 mg Verapamil Trandolapril) in order to commit suicide and applied to our emergency department with AV complete block development of the syncope

Kaynakça

  • Cohen V, Jellinek SP, Fancher L, Sangwan G, Wakslak M, Marquart E, Farahani C. Tarka(R) (Trandolapril/Verapamil Hydrochloride Extended-Release) overdose. J Emerg Med 2009 (doi:10.1016/j. jemermed.2008.10.015).
  • Heard K, Kline JA. Calcium Channel Blockers. In: Tintinalli JE, Kelen GD, Stapczynki JS, editors. Emergency medicine a com- prehensive study guide.McGraw&Hill; 6th ed. 2004. p. 1108-12.
  • Gokel Y, Paydas S, Duru M. High-dose verapamil-trandolapril in- duced rhabdomyolysis and acute renal failure. Am J Emerg Med 2000;18:738-9.
  • Gokel Y, Paydas S, Acikalin A, Bozkurt A. High-dose verapamil + trandolapril-induced thrombotic microangiopathy. Haematologia (Budap) 2002;32: 281-5.
  • Lucas C, Christie GA, Waring WS. Rapid onset of haemodynamic effects after angiotensin converting enzyme-inhibitor overdose: implications for initial patient triage. Emerg Med J 2006;23:854-7.
  • Chanmugam A, Keith Thomasset K, Antihypertensive Agent Tox- icity. In: Tintinalli JE, Kelen GD, Stapczynki JS, editors. Emer- gency medicine a comprehensive study guide.McGraw&Hill; 6th ed. 2004. p. 1112-7.
  • Batalis NI, Harley RA, Schandl CA. Verapamil toxicity: an un- usual case report and review of the literature. Am J Forensic Med Pathol 2007;28:137-40.
  • Kavalcı C, Durukan P, Özbay Y, Kalsiyum Kanal Blokörü Ze- hirlenmesi: Olgu Sunumu F.Ü. Sağ. Bil. Derg 2007;21:85-86.
  • Boyer EW, Duic PA, Evans A. Hyperinsulinemia/euglycemia ther- apy for calcium channel blocker poisoning. Pediatr Emerg Care 2002;18:36-7.
  • Hasin T, Leibowitz D, Antopolsky M, Chajek-Shaul T. The use of low-dose insulin in cardiogenic shock due to combined overdose of verapamil, enalapril and metoprolol. Cardiology 2006;106:233-6.

Sabit Dozlu Kombine Antihipertansif Ajanlarla Zehirlenme: Olgu Sunumu

Yıl 2011, Cilt: 2 Sayı: 2, 47 - 49, 01.04.2011

Öz

Zehirlenmeler acil servis başvurularının önemli bir kısmını
oluşturmaktadır. Kombine antihipertansif ilaçların esansiyel hipertansiyon tedavisinde kullanımı yaygınlaşmaktadır, ancak bu ilaçların intihar
amaçlı aşırı alımı sık görülmemektedir. Kombine tedavi seçeneklerden
biri de anjiotensin konverting enzim inhibitörleri ve kalsiyum kanal
blokerleridir. Bu ilaçların aşırı alımına bağlı sinus bradikardisi, ciddi
hipotansiyon ve AV bloklar görülebilir. Bunlar zamanında ve etkin
şekilde tedavi edilmezse ciddi sonuçlar ortaya çıkabilir. Bu çalışmada,
Tarka forte tablet® (240 mg Verapamil + 4 mg Trandolapril) adlı ilaçtan
13 adet özkıyım amaçlı alan, AV tam blok gelişen ve senkop nedeniyle acil servisimize başvuran 17 yaşında bir hastanın literatür ışığında
tartışılması amaçlanmıştır.

Kaynakça

  • Cohen V, Jellinek SP, Fancher L, Sangwan G, Wakslak M, Marquart E, Farahani C. Tarka(R) (Trandolapril/Verapamil Hydrochloride Extended-Release) overdose. J Emerg Med 2009 (doi:10.1016/j. jemermed.2008.10.015).
  • Heard K, Kline JA. Calcium Channel Blockers. In: Tintinalli JE, Kelen GD, Stapczynki JS, editors. Emergency medicine a com- prehensive study guide.McGraw&Hill; 6th ed. 2004. p. 1108-12.
  • Gokel Y, Paydas S, Duru M. High-dose verapamil-trandolapril in- duced rhabdomyolysis and acute renal failure. Am J Emerg Med 2000;18:738-9.
  • Gokel Y, Paydas S, Acikalin A, Bozkurt A. High-dose verapamil + trandolapril-induced thrombotic microangiopathy. Haematologia (Budap) 2002;32: 281-5.
  • Lucas C, Christie GA, Waring WS. Rapid onset of haemodynamic effects after angiotensin converting enzyme-inhibitor overdose: implications for initial patient triage. Emerg Med J 2006;23:854-7.
  • Chanmugam A, Keith Thomasset K, Antihypertensive Agent Tox- icity. In: Tintinalli JE, Kelen GD, Stapczynki JS, editors. Emer- gency medicine a comprehensive study guide.McGraw&Hill; 6th ed. 2004. p. 1112-7.
  • Batalis NI, Harley RA, Schandl CA. Verapamil toxicity: an un- usual case report and review of the literature. Am J Forensic Med Pathol 2007;28:137-40.
  • Kavalcı C, Durukan P, Özbay Y, Kalsiyum Kanal Blokörü Ze- hirlenmesi: Olgu Sunumu F.Ü. Sağ. Bil. Derg 2007;21:85-86.
  • Boyer EW, Duic PA, Evans A. Hyperinsulinemia/euglycemia ther- apy for calcium channel blocker poisoning. Pediatr Emerg Care 2002;18:36-7.
  • Hasin T, Leibowitz D, Antopolsky M, Chajek-Shaul T. The use of low-dose insulin in cardiogenic shock due to combined overdose of verapamil, enalapril and metoprolol. Cardiology 2006;106:233-6.
Toplam 10 adet kaynakça vardır.

Ayrıntılar

Diğer ID JA36MG86TF
Bölüm Case Report
Yazarlar

Sevdegül Karadaş Bu kişi benim

İrfan Aydın Bu kişi benim

Mustafa Tuncer Bu kişi benim

Yemlihan Ceylan Bu kişi benim

Yayımlanma Tarihi 1 Nisan 2011
Gönderilme Tarihi 1 Nisan 2011
Yayımlandığı Sayı Yıl 2011 Cilt: 2 Sayı: 2

Kaynak Göster

APA Karadaş, S., Aydın, İ., Tuncer, M., Ceylan, Y. (2011). Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report. Journal of Emergency Medicine Case Reports, 2(2), 47-49.
AMA Karadaş S, Aydın İ, Tuncer M, Ceylan Y. Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report. Journal of Emergency Medicine Case Reports. Nisan 2011;2(2):47-49.
Chicago Karadaş, Sevdegül, İrfan Aydın, Mustafa Tuncer, ve Yemlihan Ceylan. “Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report”. Journal of Emergency Medicine Case Reports 2, sy. 2 (Nisan 2011): 47-49.
EndNote Karadaş S, Aydın İ, Tuncer M, Ceylan Y (01 Nisan 2011) Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report. Journal of Emergency Medicine Case Reports 2 2 47–49.
IEEE S. Karadaş, İ. Aydın, M. Tuncer, ve Y. Ceylan, “Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report”, Journal of Emergency Medicine Case Reports, c. 2, sy. 2, ss. 47–49, 2011.
ISNAD Karadaş, Sevdegül vd. “Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report”. Journal of Emergency Medicine Case Reports 2/2 (Nisan 2011), 47-49.
JAMA Karadaş S, Aydın İ, Tuncer M, Ceylan Y. Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report. Journal of Emergency Medicine Case Reports. 2011;2:47–49.
MLA Karadaş, Sevdegül vd. “Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report”. Journal of Emergency Medicine Case Reports, c. 2, sy. 2, 2011, ss. 47-49.
Vancouver Karadaş S, Aydın İ, Tuncer M, Ceylan Y. Fixed Dose Combined Antihypertensive Agents Poisoning: Case Report. Journal of Emergency Medicine Case Reports. 2011;2(2):47-9.