A report of recurring pregnancy-induced Cushing's syndrome
Yıl 2020,
Cilt: 11 Sayı: 1, 13 - 16, 10.09.2020
Mitra Niafar
,
Amir Bahrami
Fatemeh Ghorbani
Nasser Aghamohammadzadeh
Vahideh Sadra
Nader Nader Djalal
Öz
Introduction: The incidence of pregnancy-induced
Cushing's syndrome (CS) is very low. However, the diagnosis of CS in pregnant
patients is very difficult because of an overlapping signs and symptoms.
Case
report: Herein,
a 20-year-old pregnant patient was reported that was afflicted by gestational
CS during two pregnancies; termination of pregnancy was carried out in both
cases. Bilateral adrenal hypertrophy was reported in magnetic resonance
imaging. Following therapeutic abortion, signs of chemical evidence of CS was
thoroughly regressed within a few months after each abortion without any
treatment.
Conclusion: Due to the temporal relation between the
occurrence of CS after each pregnancy the diagnosis of gestational
hypercortisolism was made, and for further pregnancies bilateral adrenalectomy
was recommended.
Destekleyen Kurum
Tabriz University of Medical Sciences, Tabriz, Iran
Teşekkür
Authors would like to acknowledge Dr. Nader Nader Djalal at Department of Anesthesiology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY 14203, USA for his great help.
Kaynakça
- 1. Vilar L, Freitas Mda C, Lima LH, Lyra R, Kater CE. (2007). Cushing's syndrome in pregnancy: an overview. Arq Bras Endocrinol Metabol. 51(8):1293-302.
- 2. Abbassy M, Kshettry VR, Hamrahian AH, Johnston PC, Dobri GA, Avitsian R, et al. (2015). Surgical management of recurrent Cushing's disease in pregnancy: A case report. Surg Neurol Int. 6(Suppl 25):S640-5.
- 3. Kita M, Sakalidou M, Saratzis A, Ioannis S, Avramides A. (2007). Cushing’s syndrome in pregnancy: report of a case and review of the literature. Hormones-Athens. 6(3):242-46.
- 4. Niafar M, Nader ND. (2015). Adiponectin as serum biomarker of insulin resistance in patients with polycystic ovarian syndrome. Gynecol Endocrinol. 31(6):473-6.
- 5. Lindsay JR, Jonklaas J, Oldfield EH, Nieman LK. (2005). Cushing's syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab. 90(5):3077-83.
- 6. Shaw JA, Pearson DW, Krukowski ZH, Fisher PM, Bevan JS. (2002). Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation. Eur J Obstet Gynecol Reprod Biol. 105(2):189-91.
- 7. Bevans JS, Gough MH, Gillmere MDG, Burke CW. (1987). Cushing’s syndrome in pregnancy: The timing of definitive treatment. Clinical Endocrinology. 27(2):225-33.
- 8. Nassi R, Ladu C, Vezzosi C, Mannelli M. (2015). Cushing's syndrome in pregnancy. Gynecol Endocrinol. 31(2):102-4.
- 9. Sam S, Molitch ME. (2003). Timing and special concerns regarding endocrine surgery during pregnancy. Endocrinol Metab Clin North Am. 32(2):337-54.
Yıl 2020,
Cilt: 11 Sayı: 1, 13 - 16, 10.09.2020
Mitra Niafar
,
Amir Bahrami
Fatemeh Ghorbani
Nasser Aghamohammadzadeh
Vahideh Sadra
Nader Nader Djalal
Kaynakça
- 1. Vilar L, Freitas Mda C, Lima LH, Lyra R, Kater CE. (2007). Cushing's syndrome in pregnancy: an overview. Arq Bras Endocrinol Metabol. 51(8):1293-302.
- 2. Abbassy M, Kshettry VR, Hamrahian AH, Johnston PC, Dobri GA, Avitsian R, et al. (2015). Surgical management of recurrent Cushing's disease in pregnancy: A case report. Surg Neurol Int. 6(Suppl 25):S640-5.
- 3. Kita M, Sakalidou M, Saratzis A, Ioannis S, Avramides A. (2007). Cushing’s syndrome in pregnancy: report of a case and review of the literature. Hormones-Athens. 6(3):242-46.
- 4. Niafar M, Nader ND. (2015). Adiponectin as serum biomarker of insulin resistance in patients with polycystic ovarian syndrome. Gynecol Endocrinol. 31(6):473-6.
- 5. Lindsay JR, Jonklaas J, Oldfield EH, Nieman LK. (2005). Cushing's syndrome during pregnancy: personal experience and review of the literature. J Clin Endocrinol Metab. 90(5):3077-83.
- 6. Shaw JA, Pearson DW, Krukowski ZH, Fisher PM, Bevan JS. (2002). Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation. Eur J Obstet Gynecol Reprod Biol. 105(2):189-91.
- 7. Bevans JS, Gough MH, Gillmere MDG, Burke CW. (1987). Cushing’s syndrome in pregnancy: The timing of definitive treatment. Clinical Endocrinology. 27(2):225-33.
- 8. Nassi R, Ladu C, Vezzosi C, Mannelli M. (2015). Cushing's syndrome in pregnancy. Gynecol Endocrinol. 31(2):102-4.
- 9. Sam S, Molitch ME. (2003). Timing and special concerns regarding endocrine surgery during pregnancy. Endocrinol Metab Clin North Am. 32(2):337-54.