Akut Pankreatit ile Başvuran Abdominal Aort Anevrizması: Nadir Görülen Bir Klinik Bulgu
Yıl 2025,
Cilt: 16 Sayı: 1, 28 - 30, 28.03.2025
Mevlana Gül
,
Yunus Emre Ek
Öz
Özet
Giriş: Akut pankreatit, başlıca safra taşı ve alkol kötüye kullanımının neden olduğu, pankreas enzimlerinin yükselmesiyle ilişkili pankreasın enflamatuar bir durumudur.
Olgu sunumu: Bu makalede, abdominal aort anevrizması (AAA) ve akut pankreatitin bir arada görüldüğü 82 yaşında nadir bir kadın olgu sunulmuştur. Tipik akut pankreatit semptomları gösteren hastaya ileri görüntüleme ile AAA tanısı konuldu.
Sonuç: Bu çalışma, AAA ve AP arasındaki mekanik ve enflamatuar etkileşimlerin altını çizmekte ve anevrizma rüptürü veya tekrarlayan pankreatit dahil olmak üzere eşzamanlı presentasyon potansiyelini vurgulamaktadır. Bu tür vakaların ele alınmasında ileri görüntüleme ve multidisipliner yönetimin önemini vurgulamaktadır. Patofizyolojik etkileşimleri ortaya çıkarmak ve bu tür komorbid durumlar için klinik sonuçları optimize etmek için daha fazla araştırma yapılması önerilmektedir.
Kaynakça
- 1. Lankisch, P.G., M. Apte, and P.A. Banks, Acute pancreatitis. The Lancet, 2015. 386(9988):
p. 85-96.
- 2. Williams, A., et al., Comprehensive Review Of The Etiologic Causes Of Acute Pancreatitis.
- 3. Bálint, E.R., et al., Assessment of the course of acute pancreatitis in the light of aetiology: a
systematic review and meta-analysis. Scientific Reports, 2020. 10(1): p. 17936.
- 4. Walkowska, J., et al., The pancreas and known factors of acute pancreatitis. Journal of
clinical medicine, 2022. 11(19): p. 5565.
- 5. Forsmark Ch, E., S.S. Vege, and C.M. Wilcox, Acute Pancreatitis. N Engl J Med, 2017.
376(6): p. 598-9.
- 6. Wang, G.-J., et al., Acute pancreatitis: etiology and common pathogenesis. World journal of
gastroenterology: WJG, 2009. 15(12): p. 1427.
- 7. Bhatia, M., et al., Pathophysiology of acute pancreatitis. Pancreatology, 2005. 5(2-3): p.
132-144.
- 8. Chen, J., L. Hu, and Z. Liu, Medical treatments for abdominal aortic aneurysm: an
overview of clinical trials. Expert Opinion on Investigational Drugs, 2024. 33(9): p. 979-992.
- 9. Lin, J., et al., Status of diagnosis and therapy of abdominal aortic aneurysms. Frontiers in
cardiovascular medicine, 2023. 10: p. 1199804.
- 10. Veraldi, G., et al., Treatment of abdominal aortic aneurysms associated with pancreatic
tumors: personal experience and review of the literature (1967-2006). International angiology,
2008. 27(6): p. 539.
- 11. Chen, C.-Y., et al., Abdominal aortic aneurysm compression is probably responsible for
the recurrent episodes of acute pancreatitis: case report. Hepato-gastroenterology, 1999.
46(28): p. 2625-2627.
- 12. Wachal, K., et al., Acute pancreatitis complicated by rupture of abdominal aortic
aneurysm. Gastroenterology Review/Przegląd Gastroenterologiczny, 2016. 11(2): p. 136-138.
- 13. Lieder, H.R., et al., Acute occlusion of the ductus pancreaticus due to abdominal aortic
aneurysm: uncommon cause of silent sever acute pancreatitis–a case report and review of the
litterature. Case Reports in Internal Medicine, 2016. 3(1).
- 14. Drissi, M., et al., Severe acute pancreatitis after surgical treatment of a ruptured
abdominal aortic aneurysm. Annals of Vascular Surgery, 2009. 23(6): p. 785. e5-785. e7.
Abdominal Aortic Aneurysm Presenting with Acute Pancreatitis: A Rare Clinical Manifestation
Yıl 2025,
Cilt: 16 Sayı: 1, 28 - 30, 28.03.2025
Mevlana Gül
,
Yunus Emre Ek
Öz
Summary
Introduction: Acute pancreatitis is an inflammatory condition of the pancreas associated with elevated pancreatic enzymes, mainly caused by gallstones and alcohol abuse.
Case report: In this article, we report a rare case of an 82-year-old woman with abdominal aortic aneurysm (AAA) and acute pancreatitis. The patient presented with typical acute pancreatitis symptoms and AAA was diagnosed by further imaging.
Conclusion: This study underlines the mechanical and inflammatory interactions between AAA and acute pancreatitis and highlights the potential for concurrent presentation, including aneurysm rupture or recurrent pancreatitis. It emphasises the importance of advanced imaging and multidisciplinary management in handling such cases. Further research is recommended to uncover pathophysiological interactions and optimise clinical outcomes for such comorbid conditions.
Kaynakça
- 1. Lankisch, P.G., M. Apte, and P.A. Banks, Acute pancreatitis. The Lancet, 2015. 386(9988):
p. 85-96.
- 2. Williams, A., et al., Comprehensive Review Of The Etiologic Causes Of Acute Pancreatitis.
- 3. Bálint, E.R., et al., Assessment of the course of acute pancreatitis in the light of aetiology: a
systematic review and meta-analysis. Scientific Reports, 2020. 10(1): p. 17936.
- 4. Walkowska, J., et al., The pancreas and known factors of acute pancreatitis. Journal of
clinical medicine, 2022. 11(19): p. 5565.
- 5. Forsmark Ch, E., S.S. Vege, and C.M. Wilcox, Acute Pancreatitis. N Engl J Med, 2017.
376(6): p. 598-9.
- 6. Wang, G.-J., et al., Acute pancreatitis: etiology and common pathogenesis. World journal of
gastroenterology: WJG, 2009. 15(12): p. 1427.
- 7. Bhatia, M., et al., Pathophysiology of acute pancreatitis. Pancreatology, 2005. 5(2-3): p.
132-144.
- 8. Chen, J., L. Hu, and Z. Liu, Medical treatments for abdominal aortic aneurysm: an
overview of clinical trials. Expert Opinion on Investigational Drugs, 2024. 33(9): p. 979-992.
- 9. Lin, J., et al., Status of diagnosis and therapy of abdominal aortic aneurysms. Frontiers in
cardiovascular medicine, 2023. 10: p. 1199804.
- 10. Veraldi, G., et al., Treatment of abdominal aortic aneurysms associated with pancreatic
tumors: personal experience and review of the literature (1967-2006). International angiology,
2008. 27(6): p. 539.
- 11. Chen, C.-Y., et al., Abdominal aortic aneurysm compression is probably responsible for
the recurrent episodes of acute pancreatitis: case report. Hepato-gastroenterology, 1999.
46(28): p. 2625-2627.
- 12. Wachal, K., et al., Acute pancreatitis complicated by rupture of abdominal aortic
aneurysm. Gastroenterology Review/Przegląd Gastroenterologiczny, 2016. 11(2): p. 136-138.
- 13. Lieder, H.R., et al., Acute occlusion of the ductus pancreaticus due to abdominal aortic
aneurysm: uncommon cause of silent sever acute pancreatitis–a case report and review of the
litterature. Case Reports in Internal Medicine, 2016. 3(1).
- 14. Drissi, M., et al., Severe acute pancreatitis after surgical treatment of a ruptured
abdominal aortic aneurysm. Annals of Vascular Surgery, 2009. 23(6): p. 785. e5-785. e7.