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Renal transplantasyon sonrası kalistenik egzersiz programının inflamatuar belirleyiciler, yaşam kalitesi ve egzersiz kapasitesi üzerine etkisi: randomize kontrollü bir çalışma

Yıl 2020, Cilt: 7 Sayı: 1, 1 - 10, 31.03.2020

Öz

Amaç: Bu çalışmanın amacı, kalistenik egzersiz eğitiminin böbrek nakli sonrası inflamatuar belirleyiciler, biyokimyasal değerler, yaşam kalitesi ve egzersiz kapasitesi üzerindeki etkilerini araştırmaktır.

Yöntem: Bu çalışmaya renal transplantasyon yapılan 29 hasta dahil edildi. Hastalar rastgele olarak kalistenik egzersiz ve kontrol grupları olmak üzere 2 gruba ayrıldı. Tüm hastaların tam kan sayımı, serum kreatinin, toplam protein, albümin, glikoz, kolesterol, trigliserit, düşük ve yüksek yoğunluklu lipoprotein, C reaktif protein ve interlökin 6 düzeyleri uygun biyokimyasal yöntemlerle belirlendi. Genel yaşam kalitesi Kısa Form 36 (SF-36), hastalığa özgü yaşam kalitesi Böbrek Hastalığı Yaşam Kalitesi Anketi (KDQOL-SF) ile değerlendirildi ve egzersiz kapasitesi 6 Dakika Yürüme Testi (6-DYT) ile ölçüldü. Egzersiz grubundaki kişilere bireysel olarak gözetimli egzersiz ve ev egzersizleri verildi. Kontrol grubundaki katılımcılara sadece eğitim seansı verildi ve mevcut tıbbi tedavilerine devam ettiler.

Bulgular: Yaşam kalitesi ölçümünde sosyal fonksiyon alt parametresinde egzersiz grubu daha iyiydi (p<0,05). Hasta memnuniyeti düzeyi de benzer şekilde egzersiz grubunda daha iyiydi (p<0,05). Serum biyokimyasal düzeyleri, KDQOL-SF ve 6-DYT değerlendirmeleri gruplar arasında istatistiksel olarak farklı değildi (p>0,05). Egzersiz grubunda hemoglobin değerlerinde artış ve 6-DYT'de 18 m iyileşme gözlendi (p<0,05).

Sonuç: Bu çalışma, kalistenik egzersiz eğitiminin böbrek nakli olan hastaların egzersiz kapasitesini, hemoglobin düzeylerini, memnuniyet düzeylerini ve bazı yaşam kalitesi parametrelerini arttırdığını ve bu sonuçların böbrek nakli sonuçlarını da olumlu yönde etkilediğini göstermiştir. 

Kaynakça

  • 1. Yalçın AU, Akpolat T. Kronik Böbrek Yetmezliği [Internet]. [Access date 23 Nisan 2017]. Access address: http://www.tsn.org.tr/folders/file/kronik_bobrek _yetmezligi.pdf.
  • 2. Blair SN, Brodney, S. Effects of physical inactivity and obesity on morbidity and mortality: current evidence and research issues. Med Sci Sports Exerc. 1999;31:646-662.
  • 3. Smith JK. Exercise and atherogenesis. Exerc Sport Sci Rev. 2001;29:49-53.
  • 4. Koca HB, Yıldırım İ, Işık Ö, et al. Genç yetişkin kadınlarda düzenli aerobik egzersizlerin inflamatuar belirteçler üzerine etkisi. Spor ve Performans Araştırmaları Dergisi. 2018;25-34.
  • 5. Surgit O, Ersöz G, Gürsel Y, et al. Effects of exercise training on specific immune parameters in transplant recipients. Transplant Proc. 2001;33:3298.
  • 6. Romano G, Simonella R, Falletti E, et al. Physical training effects in renal transplant recipients. Clin Transplant. 2010;24:510-514.
  • 7. Baştuğ ZÖ, Gültekin Z. Fibromiyalji sendromu olan kadınlarda iki farklı egzersiz programının karşılaştırılması. Turk J Physiother Rehabil. 2008;19:15-23.
  • 8. Normandin EA, McCusker C, Connors M, et al. An evaluation of two approaches to exercise conditioning in pulmonary Rehabilitation. Chest. 2002;121:1085-1091.
  • 9. Güngen C, Ertan T, Eker E, et al. Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population. Turk Psikiyatri Derg. 2002;13:273-281.
  • 10. Portney LG, Watkins MP. Foundations of Clinical Research: Applications to practice. 3rd ed. 2008. Cohen J. Statistical power analyisis for the behavioral sciences. 2nd ed. Newyork: Academic Press; 1997.
  • 11. htpp://www.graphpad.com. Access date: August 30, 2015.
  • 12. Gómez-Besteiro MI, Santiago-Pérez MI, Alonso- Hernández A, et al. Validity and reliability of the SF-36 Questionnaire in patients on the waiting list for a kidney transplant and transplant patients. Am J Nephrol. 2004;24:346-351.
  • 13. Kocyigit H, Aydemir O, Fisek G, et al. Validity and reliability of Turkish version of SF-36. J Drug Ther. 1999;12:102.
  • 14. Malindretos P, Sarafidis P, Spaia S, et al. Adaptation and validation of the Kidney Disease Quality of Life-Short Form Questionnaire in the Greek Language. J Nephrol. 2010;31:9-14.
  • 15. Valderrábano F, Jofre R, López-Gómez JM. Quality of life in end-stage renal disease patients. Am J Kidney Dis. 2001;38:443-464.
  • 16. Yıldırım A, Ogutmen B, Bektas G, et al. Translation, cultural adaptation, initial reliability, and validation of the Kidney Disease and Quality of Life-Short Form (KDQOL-SF 1.3) in Turkey. Transplant Proc. 2007;39:51-54.
  • 17. ATS statement. Guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166:111-117.
  • 18. Borg G. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982;14:377- 381.
  • 19. Brokelman RB, Haverkamp D, Van Loon C, et al. The validation of the visuel analogue scale for patient satisfaction after total hip arthroplasty. Eur Orthop Traumatol. 2012;3:101-105.
  • 20. Duruturk N, Arıkan H, Ulubay G, et al. A comparison of calisthenic and cycle exercise training in chronic obstructive pulmonary disease patients: A randomized controlled trial. Expert Rev Respir Med. 2016;10:99-108.
  • 21. Fischer CP. Interleukin-6 in acute exercise and training: What is the biological relevance? interleukin-6 in acute exercise and training. Exerc Immunol Rev. 2006;12:6-33.
  • 22. Özdemir E. Karaciğer ve Böbrek Yetmezlikli Hastaların İnvaziv Enfeksiyonlarında Crp Yanıtının Değerlendirilmesi. [PhD Thesis]. Ankara: Başkent University: 2009.
  • 23. Chen G, Gao L, Li X. Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis. Ren Fail. 2019;41:408-418.
  • 24. Gleeson PB, Protas EJ. Oxygen consumption during calisthenic exercise in women with coronary artery disease. Phys Ther. 1989;69:260-263.
  • 25. Lofaro D, Greco R, Papalia T, et al. Increasing levels of hemoglobin improve renaltransplantation outcomes. Transplant Proc. 2011;43:1036-1038.
  • 26. Schechter A, Gafter-Gvili A, Shepshelovich D, et al. Post renal transplant anemia: Severity, causes and their association with graft and patient survival. BMC Nephrology. 2019;20:51.
  • 27. Wei Yun Wang D, Sills LL, MacDonald SB, et al. Active video gaming in patients with renal transplant: a pilot study. Transplant. Res. 2014;3:15.
  • 28. Carvalho EV, Reboredo MM, Gomes EP, et al. Physical activity in daily life assessed by an accelerometer in kidney transplant recipients and hemodialysis patients. Transplant Proc. 2014;46:1713-1717.
  • 29. Cury JL, Brunetto AF, Aydos RD. Negative effects of chronic kidney failure on lung function and functional capacity. Rev Bras Fisioter. 2010;14:91-98.
  • 30. Üstündağ H, Gül A, Zengin N, et al. Böbrek nakli yapılan hastalarda yaşam kalitesi. Fırat Sağlık Hizmetleri Dergisi. 2007;2:117-126.
  • 31. Riess K, Haykowsky M, Lawrance C, et al. Exercise training improves aerobic capacity, muscle strength, and quality of life in renal transplant recipients. Appl Physiol Nutr Metab. 2014;39:566-571.
  • 32. Oskay D, Atalay Güzel N, Çamcı E, et al. Effects of improving physical activity level on quality of life and functional status of patients receiving peritoneal dialysis. Turkish journal of nephrology. 2014;23:33-39.
  • 33. Matialagoni AM, Catizone L, Mandini S, et al. Acute and long-term effects of an exercise program for dialysis patients prescribed in hospital and performed at home. J Nephrol. 2008;21:871-878.
  • 34. Calella P, Hernández-Sánchez S, Garofalo C, et al. Exercise training in kidney transplant recipients: a systematic review. J Nephrol. 2019;32:567-579.
  • 35. Lendraitiene E, Lanevskaite E, Petrusevicienė D, et al. Effect of different physical therapy program on renal transplant recipients’ physical activity, grip strength and psychoemotional status and the associations between these indices. Transplant Proc. 2018;50:3338-3345.
  • 36. Greenwood SA, Koufaki P, Mercer TH, et al. Aerobic or resistance training and pulse wave velocity in kidney transplant recipients: A 12- week pilot randomized controlled trial the Exercise in renal transplant [ExeRT] trial. Am J Kidney Dis. 2015;66:689-698.

Effect of calisthenic exercise program on inflammatory markers, quality of life and exercise capacity after renal transplantation: a randomized controlled study

Yıl 2020, Cilt: 7 Sayı: 1, 1 - 10, 31.03.2020

Öz

Purpose: The aim of this study was to investigate the effects of calisthenic exercise training on inflammatory markers, biochemical values, quality of life and exercise capacity after renal transplantation.

Methods: This study involved 29 patients who underwent renal transplantation. Patients were randomly divided into 2 groups, calisthenic exercise and control groups. All patients’ complete blood counts, serum creatinine, total protein, albumin, glucose, cholesterol, triglyceride, low- and high-density lipoprotein, C reactive protein and interleukin 6 levels were determined by appropriate biochemical methods. General quality of life was assessed with the Short Form 36 (SF-36), disease-specific quality of life was assessed with the Kidney Disease Quality of Life Questionnaire (KDQOL-SF) and exercise capacity was measured by the 6-Minute Walk Test (6-MWT). Supervised and home exercises were given to exercise group individually. Participants in the control group just received the education session and continued their current medical therapies.

Results: The social function subparameter of quality of life measurement was better in the Exercise Group (p<0.05). Level of patient satisfaction also was better in the Exercise Group (p<0.05). Serum biochemical levels, KDQOL-SF and 6-MWT evaluations were not statistically different between the groups (p>0.05). There was an increase in hemoglobin values and 18-meter improvement in 6-MWT in the exercise group (p<0.05).

Conclusion: This study showed that calisthenic exercise training increased exercise capacity, hemoglobin levels, satisfaction levels and some parameters of quality of life in renal transplantation patients and these results positively affect the outcomes of renal transplantation. 


Kaynakça

  • 1. Yalçın AU, Akpolat T. Kronik Böbrek Yetmezliği [Internet]. [Access date 23 Nisan 2017]. Access address: http://www.tsn.org.tr/folders/file/kronik_bobrek _yetmezligi.pdf.
  • 2. Blair SN, Brodney, S. Effects of physical inactivity and obesity on morbidity and mortality: current evidence and research issues. Med Sci Sports Exerc. 1999;31:646-662.
  • 3. Smith JK. Exercise and atherogenesis. Exerc Sport Sci Rev. 2001;29:49-53.
  • 4. Koca HB, Yıldırım İ, Işık Ö, et al. Genç yetişkin kadınlarda düzenli aerobik egzersizlerin inflamatuar belirteçler üzerine etkisi. Spor ve Performans Araştırmaları Dergisi. 2018;25-34.
  • 5. Surgit O, Ersöz G, Gürsel Y, et al. Effects of exercise training on specific immune parameters in transplant recipients. Transplant Proc. 2001;33:3298.
  • 6. Romano G, Simonella R, Falletti E, et al. Physical training effects in renal transplant recipients. Clin Transplant. 2010;24:510-514.
  • 7. Baştuğ ZÖ, Gültekin Z. Fibromiyalji sendromu olan kadınlarda iki farklı egzersiz programının karşılaştırılması. Turk J Physiother Rehabil. 2008;19:15-23.
  • 8. Normandin EA, McCusker C, Connors M, et al. An evaluation of two approaches to exercise conditioning in pulmonary Rehabilitation. Chest. 2002;121:1085-1091.
  • 9. Güngen C, Ertan T, Eker E, et al. Reliability and validity of the standardized Mini Mental State Examination in the diagnosis of mild dementia in Turkish population. Turk Psikiyatri Derg. 2002;13:273-281.
  • 10. Portney LG, Watkins MP. Foundations of Clinical Research: Applications to practice. 3rd ed. 2008. Cohen J. Statistical power analyisis for the behavioral sciences. 2nd ed. Newyork: Academic Press; 1997.
  • 11. htpp://www.graphpad.com. Access date: August 30, 2015.
  • 12. Gómez-Besteiro MI, Santiago-Pérez MI, Alonso- Hernández A, et al. Validity and reliability of the SF-36 Questionnaire in patients on the waiting list for a kidney transplant and transplant patients. Am J Nephrol. 2004;24:346-351.
  • 13. Kocyigit H, Aydemir O, Fisek G, et al. Validity and reliability of Turkish version of SF-36. J Drug Ther. 1999;12:102.
  • 14. Malindretos P, Sarafidis P, Spaia S, et al. Adaptation and validation of the Kidney Disease Quality of Life-Short Form Questionnaire in the Greek Language. J Nephrol. 2010;31:9-14.
  • 15. Valderrábano F, Jofre R, López-Gómez JM. Quality of life in end-stage renal disease patients. Am J Kidney Dis. 2001;38:443-464.
  • 16. Yıldırım A, Ogutmen B, Bektas G, et al. Translation, cultural adaptation, initial reliability, and validation of the Kidney Disease and Quality of Life-Short Form (KDQOL-SF 1.3) in Turkey. Transplant Proc. 2007;39:51-54.
  • 17. ATS statement. Guidelines for the six-minute walk test. Am J Respir Crit Care Med. 2002;166:111-117.
  • 18. Borg G. Psychophysical bases of perceived exertion. Med Sci Sports Exerc. 1982;14:377- 381.
  • 19. Brokelman RB, Haverkamp D, Van Loon C, et al. The validation of the visuel analogue scale for patient satisfaction after total hip arthroplasty. Eur Orthop Traumatol. 2012;3:101-105.
  • 20. Duruturk N, Arıkan H, Ulubay G, et al. A comparison of calisthenic and cycle exercise training in chronic obstructive pulmonary disease patients: A randomized controlled trial. Expert Rev Respir Med. 2016;10:99-108.
  • 21. Fischer CP. Interleukin-6 in acute exercise and training: What is the biological relevance? interleukin-6 in acute exercise and training. Exerc Immunol Rev. 2006;12:6-33.
  • 22. Özdemir E. Karaciğer ve Böbrek Yetmezlikli Hastaların İnvaziv Enfeksiyonlarında Crp Yanıtının Değerlendirilmesi. [PhD Thesis]. Ankara: Başkent University: 2009.
  • 23. Chen G, Gao L, Li X. Effects of exercise training on cardiovascular risk factors in kidney transplant recipients: a systematic review and meta-analysis. Ren Fail. 2019;41:408-418.
  • 24. Gleeson PB, Protas EJ. Oxygen consumption during calisthenic exercise in women with coronary artery disease. Phys Ther. 1989;69:260-263.
  • 25. Lofaro D, Greco R, Papalia T, et al. Increasing levels of hemoglobin improve renaltransplantation outcomes. Transplant Proc. 2011;43:1036-1038.
  • 26. Schechter A, Gafter-Gvili A, Shepshelovich D, et al. Post renal transplant anemia: Severity, causes and their association with graft and patient survival. BMC Nephrology. 2019;20:51.
  • 27. Wei Yun Wang D, Sills LL, MacDonald SB, et al. Active video gaming in patients with renal transplant: a pilot study. Transplant. Res. 2014;3:15.
  • 28. Carvalho EV, Reboredo MM, Gomes EP, et al. Physical activity in daily life assessed by an accelerometer in kidney transplant recipients and hemodialysis patients. Transplant Proc. 2014;46:1713-1717.
  • 29. Cury JL, Brunetto AF, Aydos RD. Negative effects of chronic kidney failure on lung function and functional capacity. Rev Bras Fisioter. 2010;14:91-98.
  • 30. Üstündağ H, Gül A, Zengin N, et al. Böbrek nakli yapılan hastalarda yaşam kalitesi. Fırat Sağlık Hizmetleri Dergisi. 2007;2:117-126.
  • 31. Riess K, Haykowsky M, Lawrance C, et al. Exercise training improves aerobic capacity, muscle strength, and quality of life in renal transplant recipients. Appl Physiol Nutr Metab. 2014;39:566-571.
  • 32. Oskay D, Atalay Güzel N, Çamcı E, et al. Effects of improving physical activity level on quality of life and functional status of patients receiving peritoneal dialysis. Turkish journal of nephrology. 2014;23:33-39.
  • 33. Matialagoni AM, Catizone L, Mandini S, et al. Acute and long-term effects of an exercise program for dialysis patients prescribed in hospital and performed at home. J Nephrol. 2008;21:871-878.
  • 34. Calella P, Hernández-Sánchez S, Garofalo C, et al. Exercise training in kidney transplant recipients: a systematic review. J Nephrol. 2019;32:567-579.
  • 35. Lendraitiene E, Lanevskaite E, Petrusevicienė D, et al. Effect of different physical therapy program on renal transplant recipients’ physical activity, grip strength and psychoemotional status and the associations between these indices. Transplant Proc. 2018;50:3338-3345.
  • 36. Greenwood SA, Koufaki P, Mercer TH, et al. Aerobic or resistance training and pulse wave velocity in kidney transplant recipients: A 12- week pilot randomized controlled trial the Exercise in renal transplant [ExeRT] trial. Am J Kidney Dis. 2015;66:689-698.
Toplam 36 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Makaleler
Yazarlar

Ayça Tigli Bu kişi benim 0000-0002-4089-5406

Yavuz Yakut

Yayımlanma Tarihi 31 Mart 2020
Gönderilme Tarihi 5 Nisan 2019
Yayımlandığı Sayı Yıl 2020 Cilt: 7 Sayı: 1

Kaynak Göster

Vancouver Tigli A, Yakut Y. Effect of calisthenic exercise program on inflammatory markers, quality of life and exercise capacity after renal transplantation: a randomized controlled study. JETR. 2020;7(1):1-10.