ORAL COLLAGEN SUPPLEMENTS AND DETERMINATION OF THEIR POSSIBLE ADVERSE EFFECTS

Öz

Objective: Many studies on oral collagen supplements to date are on the effects of collagen supplements on joint and skin health. The beneficial effects of collagen on other functions of the body are known, but studies are insufficient. Available data show that collagen supplements, which have become an important part of the daily diet by many people, do not show any toxic effects and are considered to be safe to use. However, due to the lack of supporting data, it is necessary to draw attention to the need for additional studies on the toxicity of collagen supplements despite their frequent use. Result and Discussion: When the results of the literature reviews were examined, very little data on possible adverse effects were found. Long-term oral administration of specific collagen can cause harmful cellular damage in the body, weight loss, and disrupt the functions of target organs. It is necessary to have information about the contents of variable collagen sources and pay attention to their usage durations and amounts.

Anahtar Kelimeler

• Collagen
• oral collagen related adverse effects
• oral collagen uses
• oral collagen types

ORAL KOLAJEN TAKVİYELERİ VE OLASI ADVERS ETKİLERİNİN DEĞERLENDİRİLMESİ

Öz

Amaç: Bugüne kadar oral kolajen takviyeleri hakkında yapılan birçok çalışma kolajen takviyelerinin eklem ve cilt sağlığına üzerindeki etkileri üzerinedir. Kolajenlerin vücudun diğer fonksiyonları üzerine yararlı etkileri bilinmekte olup bunlar hakkında yapılan çalışmalar yetersiz kalmaktadır. Mevcut veriler birçok insan tarafından günlük diyetin önemli bir parçası haline gelen kolajen takviyelerinin herhangi bir toksik etkisi olmadığını, kullanımlarının güvenli olduğunu göstermektedir. Ancak yapılan çalışmalar sonucu birbirini destekleyen verilerin olmamasından dolayı kolajen takviyelerinin bu kadar sık kullanımlarına rağmen toksisiteleri üzerine ek çalışmalar yapılmasına ihtiyaç duyulmaktadır. Sonuç ve Tartışma: Yapılan literatür taramalarının sonuçları incelendiğinde, olası advers etkilere ait çok az veriye rastlanmıştır. Spesifik kolajenin uzun süreli oral uygulanması vücutta zararlı hücresel hasarlara sebep olabilir, kilo kaybına sebep olabilir, organları hedef alarak işleyişini aksatabilir. Değişken kolajen kaynaklarının içerikleri hakkında bilgi sahibi olmak ve kullanım sürelerine, kullanım miktarlarına dikkat edilmesi gerekir.

Anahtar Kelimeler

• Kolajen
• oral kolajene bağlı advers etkiler
• oral kolajen kullanım alanları
• oral kolajen tipleri

Kaynakça

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