BENİGN PROSTAT HİPERPLAZİSİ ÜZERİNDE ETKİLİ FİTOTERAPÖTİKLER

Yıl 2019, , 173 - 196, 01.06.2019

Ufuk Çalışkan , Gökşen Dilşat Durbilmez Gökmen Memiş

https://doi.org/10.33483/jfpau.459798

Öz

Amaç: İyi huylu prostat büyümesi (Benign Prostat Hiperplazisi=BPH), elli yaş
üstü erkeklerin ortalama üçte birinde görülen hem idrar depolama, boşaltma ve
boşaltma sonrası semptomlara yol açan, hem de olguların yaşam kalitesini bozan
bir durumdur. BPH’ye bağlı alt üriner sistem hastalıklarının tedavisinde
fitoterapötikler uzun zamandan beri klinik uygulamalarda yer almaktadır. Bu
çalışmanın amacı BPH tedavisinde en sık kullanılan fitoterapötikler olan
Cucurbita pepo, Epilobium sp., Hypoxis rooperi, Lycopersicon esculentum Mill.,
Pinus pinaster Aiton, Pygeum africanum, Roystonea regia (Kunth) O.F. Cook,
Secale cereale, Serenoa repens, Urtica dioica’nın etkinlikleri ve yapılan
önemli klinik çalışmaları derlemektir.

Sonuç ve Tartışma: Kanıta
dayalı tıp zemininde BPH’ye yönelik alt üriner sistem hastalıklarının
tedavisinde fitoterapötiklerin birçok semptomda düzelme sağladığı söylenmekle
birlikte çalışmalar daha fazla plasebo kontrollü, çift-kör randomize
çalışmalara ihtiyaç duyulduğunu göstermektedir.

Anahtar Kelimeler

BPH, fitoterapötikler, prostat rahatsızlıkları

EFFECTS OF PHYTOTERAPEUTICS ON BENIGN PROSTATE HYPERPLASIA

Öz

Objective: Benign prostatic hyperplasia (BPH) is a condition that causes symptoms
during urinary storage, discharge and after discharge, which are seen in an
average one third of men over the age of fifty, as well as disrupts the quality
of life. Phytotherapeutics have long been involved in clinical practice in the treatment
of lower urinary tract symptoms associated with BPH. The goal of this study is
to review pharmacological and clinical studies on Cucurbita pepo, Epilobium
sp., Hypoxis rooperi, Lycopersicon esculentum Mill., Pinus pinaster Aiton,
Pygeum africanum, Roystonea regia (Kunth) O.F. Cook, Secale cereale, Serenoa
repens, Urtica dioica, which are the most frequently used plant species in BPH
treatment.

Result and Discussion: It is argued that
phytotherapeutics improve symptoms in the treatment of lower urinary tract for
BPH, on the other hand most of the studies shows that more placebo-controlled,
double-blind randomization studies involving large patient numbers were needed.    

Anahtar Kelimeler

BPH, phytotherapeutic, prostatic disease

Kaynakça

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