TIP VE ECZACILIK ALANINDAKİ 1,2,4-TRİAZOL TÜREVLERİ VE UYGULAMA ÖNERİLERİ

Öz

Amaç: 1,2,4-triazol türevlerinin,özellikle heterosiklik iskelete sahip ve biyolojik olarak aktif bileşiklerin, sentezi, kimyasal, fizikokimyasal ve biyolojik özelliklerinin incelenmesi için yöntemlerin geliştirilmesi.

Sonuç ve Tartışma: Bu derlemede, 1,2,4-triazol türevlerinin özelliklerinin bildirildiği 40 bilimsel makale değerlendirilmiştir. Verilenher bileşik sınıfı gelecekteki çalışmalara yön verecek şekilde bildirilmiştir.1,2,4-triazol türevlerinin insandaki biyolojik etkileri hakkında yeterli çalışma olmaması, bu alanda daha fazla çalışma yapılmasını teşvik etmektedir.

Anahtar Kelimeler

• 1,2,4-triazol
• organik sentez
• biyolojik aktivite
• bibliyosemantik yöntem

Proje Numarası

2

1,2,4-TRIAZOLE DERIVATIVES IN MEDICINE AND PHARMACY AND APPLICATION PROSPECTS

Öz

Objective: Development of methods for the synthesis, studies of chemical, physico-chemical and biological properties of 1,2,4-triazole derivatives, in particular compounds with heterocyclic scaffolds and complex compounds as potential biologically active substances.

Result and Discussion: In this review, 40 scientific papers reporting the properties of 1,2,4-triazole derivatives were evaluated. Each class of compounds described in the review was reported with the prospect of forming the direction for further research.Because of there is no enough studies about biological action of 1,2,4-triazole derivatives in human, it encourages further research.

Anahtar Kelimeler

• 1,2,4-triazole
• organic synthesis
• biological activity
• bibliosemantic method

Destekleyen Kurum

Zaporizhzhia state medical university

Proje Numarası

2

Teşekkür

Dear Editors, thank You for the opportunity to publish the material in the Journal of the Faculty of Pharmacy of Ankara University

Kaynakça

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