SİTOTOKSİSİTE ÇALIŞMALARINDA KÖK HÜCRE

Yıl 2017, Cilt: 41 Sayı: 2, 1 - 14, 31.05.2017

Aysun Ökçesiz Ülkü Ündeğer Bucurgat

Öz

Amaç: Kök hücreler; sınırsız çoğalabilen, kendilerini yenileyebilen, bütün doku ve organları meydana getiren ana hücrelerdir. Farklı hücrelere dönüşebilme özelliğine sahip olan kök hücreler, hasarlı dokuyu tamir edebilme yeteneğine sahiptirler. Bu amaçla, kök hücreler, hücre temelli terapötik stratejileri geliştirmek için kapsamlı bir şekilde araştırılmaktadır. Bu yönde yapılan araştırmalarla kök hücre tedavisinin, kansere karşı korunma ve tedavisinde kullanılması oldukça umut vericidir. Bu nedenle, 21. yüzyılın en ilgi çeken alanlarından biri halini almıştır.

Sonuç ve Tartışma: Bu derlemede, sitotoksisite çalışmalarında kök hücrelerin olası fonksiyonel rolünü özetlemek amaçlanmaktadır.

Anahtar Kelimeler

kanser, kök hücre, sitotoksisite

STEM CELLS IN CYTOTOXICITY STUDIES

Öz

Objective: Stem cells; are the main cells that make up all the tissues and organs. They can reproduce themselves, which can multiply indefinitely. The stem cells, which can turn into different cells, have the ability to repair damaged tissue. Stem cells are being extensively explored to develop cell-based therapeutic strategies. It is very promising to use stem cell therapy in the prevention and treatment of cancer with the researches carried out in this direction. For this reason, stem cell studies have become one of the most interesting areas of the 21st century.

Result and Discussion: In this review, it is aimed to summarize the possible functional role of stem cells in cytotoxicity studies.

Anahtar Kelimeler

cancer, cytotoxicity, stem cell

Kaynakça

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