Araştırma Makalesi
BibTex RIS Kaynak Göster

Quality of Life and Social Support Levels in Leukemia Patients

Yıl 2021, Cilt: 3 Sayı: 3, 200 - 214, 25.12.2021

Öz

Purpose: This study aimed to determine the quality of life, level of social support, and its influencing factors in leukemia patients.
Method: This descriptive cross-sectional study included 117 leukemia patients who applied to the Hematology Outpatient Clinic of a Medical Faculty Hospital in Istanbul. Data were collected using the Patient Information Form, European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 and Multidimensional Scale of Perceived Social Support. Normality analysis, descriptive statistics, difference analysis between pairs and multiple groups and correlation analysis were used in the analysis of the data.
Results: It was determined that the global quality of life, functioning and symptom of leukemia patients were affected by personal and disease-related characteristics such as age, gender, number of children, Body Mass Index, marital status, educational status, type of leukemia, adaptation to the disease, and diagnosis, duration of treatment (p<0.05). It was determined that social support was positively correlated with the global quality of life and functioning scores of the European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 and negatively correlated with the symptoms of loss of appetite and financial difficulties (p<0.05).
Conclusion and Suggestions: Providing holistic care by nurses and taking into account the personal and disease-related characteristics of leukemia patients will improve their quality of life and social support level.

Destekleyen Kurum

Yok

Proje Numarası

Yok

Teşekkür

We thank you to Prof. Zafer BAŞLAR, Prof. Necdet SÜT for your contribution.

Kaynakça

  • Aaronson, N.K., Ahmedzai, S.A., Bergman, B., Bullinger, M., Cull, A., Duez, N.J., Filiberti, A., Flechtner, H., Fleishman, S.B., de Haes, J.C.J.M., Kaasa, S., Klee, M., Osoba, D., Razavi, D., Rofe, P.B., Schraub, S., Sneeuw, K., Sullivan, M., et al. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of National Cancer Institute, 85(5), 365-376. https://doi.org/10.1093/jnci/85.5.365.
  • Albercht, T.A., & Bryant, A.L. (2019). Psychological and financial distress managementin adults with acute leukemia. Seminars in Oncology Nursing, 35(6),150952. DOI: 10.1016/j.soncn.2019.150952.
  • AlFayyad, I., Al-Tannir, M., Yaqub, M., Heena, H., AlMukaibil, N., Ghazwani, M., Abu-Shaheen, A. (2020). Clinically significant fatigue in adult leukemia patients: Prevalence, predictors, and ımpact on quality of life. Cureus, 12(12), e12245. DOI 10.7759/cureus.12245.
  • Alibhai, S. M. H., Leach, M., Kermalli, H., Gupta, V., Kowgier, M. E., Tomlinson, G. A., Brandwein, J., Buckstein, R. & Minden, M. D. (2007). The impact of acute myeloid leukemia and its treatment on quality of life and functional status in older adults. Critical Reviews in Oncology/Hematology, 64(1), 19–30. DOI:10.1016/j.critrevonc.2007.07.003.
  • Altmore, I., Gerds, A.T., Lessen, D., Colucci, P., Parasuraman BPharm S., Chamikara Paranagama, D., & Mesa, R.A. (2018). Correlation between MPN-SAF TSS and EORTC QLQ-C30 scores in patients with PV: Data from the reveal study. Blood, 132(Supplement 1), 2259. https://doi.org/10.1182/blood-2018-99-112937.
  • American Cancer Society (2019). Cancer Facts & Figures 2019. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2019/cancer-facts-and-figures-2019.pdf ET: 07.07.2020.
  • Ayaz, S., Yaman Efe, Ş. & Korukluoğlu, S. (2008). Level of perceived social support of patients with gynaecological cancer and affecting factors. Turkiye Klinikleri J Med Sci. 28(6),880-885. https://www.turkiyeklinikleri.com/article/en-jinekolojik-kanserli-hastalarin-algiladiklari-sosyal-destek-duzeyleri-ve-etkileyen-faktorler-52677.html
  • Aydın Bektaş, H. & Akdemir, N. (2006). The assessment of functional status in individual's who have cancer. Turkiye Klinikleri J Med Sci. 26(5):488-499. https://www.turkiyeklinikleri.com/article/en-kanserli-bireylerin-fonksiyonel-durumlarinin-degerlendirilmesi-46538.html
  • Bakan, B.A., & Guraksin, A. (2017). Factors affecting quality of life and level social support in cancer patients. Belitung Nursing Journal, 3(2), 54-64. https://doi.org/10.33546/bnj.48
  • Beser, N., & Öz, F. (2003). Kemoterapi alan Lenfomalı hastaların anksiyete-depresyon düzeyleri ve yaşam kalitesi. C.Ü. Hemşirelik Yüksek Okulu Dergisi, 7(1),47-58. http://eskidergi.cumhuriyet.edu.tr/makale/623.pdf
  • Bjordal, K., de Graeff, A., Fayers, P.M., Hammerlid, E., van Pottelsberghe, C., Curran, D., Ahlner-Elmqvist, M., Maher, E.J., Meyza, J.W., Brédart, A., Söderholm, A.L., Arraras, J.J., Feine, J.S., Abendstein, H., Morton, R.P., Pignon, T., Huguenin, P., Bottomly, A., Kaasa, S. & on behalf of the EORTC Quality of Life Group (2000). A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (The EORTC QLQ-H&N35). European Journal of Cancer, 36,213-219. DOI: 10.1016/s0959-8049(00)00186-6.
  • Borregaard Myrhøja, C., Holmegaard Nørskova, K., Jarden, M., & Rydahl-Hansen, S. (2020). The motivation to volunteer as a peer support provider to newly diagnosed patients with acute leukemia – A qualitative interview study. European Journal of Oncology Nursing, 46 (1017509, 1-6. https://doi.org/10.1016/j.ejon.2020.101750.
  • Bosshard, R., O’Reilly, K., Ralston S., Chadda, S., & Cork, D. (2018). Systematic reviews of economic burden and health-related quality of life in patients with acute myeloid leukemia. Cancer Treatment Reviews, 69, 224-232. https://doi.org/10.1016/j.ctrv.2018.07.005.
  • Buckley, S. A., Othus, M., Vainstein, V., Abkowitz, J. L., Estey, E. H., & Walter, R. B. (2014). Prediction of adverse events during intensive induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes. American Journal of Hematology, 89(4),423–428. DOI:10.1002/ajh.23661
  • Cella, D., Jensen, S.E., Webster, K., Du, H., Lai, J-S., Rosen, S., Tallman, M.S., & Yount, S. (2012). measuring health-related quality of Life in leukemia: The Functional Assessment of Cancer Therapy–Leukemia (FACT-Leu) questionnaire. value in health, 15(8),1051-1058. http://dx.doi.org/10.1016/j.jval.2012.08.2210
  • Cohen, J. (1992). Statistical Power Analysis. Current Directions in Psychological Science, 1(3), 98–101. doi:10.1111/1467-8721.ep10768783.
  • Craveiro, D. (2017). The role of personal social networks on health inequalities across European regions. Health & Place, 45,24–31. http://dx.doi.org/10.1016/j.healthplace.2017.02.007
  • Çalışkan, T., Duran, S., Karadaş, A., Ergün, S., & Tekir, Ö. (2015). Assessment the levels of life quality and social support of the cancer patients. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, 17(1), 27-36. https://dergipark.org.tr/tr/pub/kutfd/issue/10160/124910
  • Dziura, J.D., Post, L.A., Zhao, Q., Fu, Z., & Peduzzi, P. (2013). Strategies for dealing with missing data in clinical trials: from design to analysis. Yale Journal of Biology And Medicine 86, 343-358. PMC3767219. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767219/#R47
  • Efficace, F., Baccarani, M., Breccia, M., Alimena, G., Rosti, G., Cottone, F., Castagnetti, F., Lambertenghi Deliliers, G., Russo Rossi, A., Pardini, S., Gherlinzoni, F., Salvucci, M., Tiribelli, M., Vignetti, M., & Mandelli, F. (2011). Investigating personal and treatment related factors associated with adherence behavior in patients with chronic myeloid leukemia receiving long term Imatinib therapy. Blood, 118 (21), 1026. http://doi.org/10.1182/blood.V118.21.1026.1026.
  • Efficace, F., Cottone, F., Sommer, K., Kieffer, J., Aaronson, N., Fayers, P., Groenvold, M., Caocci, G., Lo Coco, F., Gaidano, G., Niscola, P., Baccarani, M., Rosti, G., Venditti, A., Emanuele, A., Fazi, P., Vignetti, M., & Giesinger, J., (2019). Validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 summary score in patients with hematologic malignancies. Value Health, 22(11), 1303-1310. https://doi.org/10.1016/j.jval.2019.06.004.
  • Eker, D., & Arkar, H. (1995). Çok Boyutlu Algılanan Sosyal Destek Ölçeğinin Faktör Yapısı, Geçerlilik ve Güvenirliği. Turkish Journal of Psychology, 10(34),45-55. https://www.psikolog.org.tr/tr/yayinlar/dergiler/1031828/tpd1300443319950000m000290.pdf
  • Eker, D., Arkar, H., & Yaldız, H. (2001). Factorial structure, validity, and reliability of revised form of the Multidimensional Scale of Perceived Social Support. Turkish Journal of Psychiatry, 12(1),17-25. http://www.turkpsikiyatri.com/c12s1/cokboyutlualgilanan.pdf
  • El-Jawahri, A., waldman, L., Greer, J., Abel G.A., Steensma, D.P., Brunner, A.M., Fathi, A.T., DeAngelo, D.J., Wadleigh, M., Hobbs, G.S., Amrein, P.C., Stone, R.M., & Temel, J.S. (2018). Quality of life and psychological distress in patients with Acute Myeloid Leukemia (AML). Blood, 132(1), 2291. http://doi.org/10.1182/blood-2018-99-114246.
  • Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007). G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39, 175-191. doi: 10.3758/bf03193146.
  • Fayers, P.M., Aaronson, N.K., Bjordal, K., Groenvold, M., Curran, D., Bottomley, A., & on behalf of the EORTC Quality of Life Group (2001). The EORTC QLQ-C30 Scoring Manual (3rd Edition). Published by: European Organisation for Research and Treatment of Cancer, Brussels. https://www.eortc.be/qol/files/SCManualQLQ-C30.pdf.
  • Guzelant, A., Goksel, T., Ozkok, S., Tasbakan, S., Aysan, T., & Bottomley, A. (2004). The European Organization for Research and Treatment of Cancer QLQ-C30: an Examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. European Journal of Cancer Care, 13,135-144. DOI: 10.1111/j.1365-2354.2003.00435.x.
  • Han, A., & Choi, J.S. (2018). Factors influencing infection prevention self-care behaviors in patients with hematologic cancer after discharge. European Journal off Oncology Nursing, 35,102-106. https://doi.org/10.1016/j.ejon.2018.06.005.
  • Herschbach, P., Keller, M., Knight, L., Brandl, T., Huber, B., Henrich, G., & Marten-Mittag, B. (2004) Psychological problems of cancer patients: a cancer distress screening with a cancer-specific questionnaire. British Journal of Cancer 91, 504–511. https://doi.org/10.1038/sj.bjc.6601986
  • Henriques, A., Silva, S., Severo, M., Fraga,, S., & Barros, H. (2020). Socioeconomic position and quality of life among older people: The mediating role of social support. Preventive Medicine, 135,1-6. https://doi.org/10.1016/j.ypmed.2020.106073
  • Hensel, M., Egerer, G., Schneeweiss, A., Goldschmidt, H., & Ho, A. D. (2002). Quality of life and rehabilitation in social and professional life after autologous stem cell transplantation. Annals of Oncology, 13(2), 209–217. doi:10.1093/annonc/mdf031
  • Holmegaard Nørskov, K., Overgaard, D., Lomborg, K., Kjeldsen, L., & Jarden, M. (2019). Patients experiences and social support needs following the diagnosis and initial treatment of acute leukemia - A qualitative study. European Journal of Oncology Nursing, 41,49-55. DOI:10.1016/j.ejon.2019.05.005
  • Holtzer-Goor, K.M., Schaafsma, M.R., Joosten, P., Posthuma, E.F.M., Wittebol, S., Huijgens, P.C., Mattijssen, E.J.M., Vreugdenhil, G., Visser, H., Peters, W.G., Erjavec, Z., Wijermans, P.W., Daenen, S.M.G.J., van der Hem, K.G., van Oers, M.H.J. & Uyl-de Groot, C.A. (2015). Quality of life of patients with chronic lymphocytic leukaemia in the Netherlands: results of a longitudinal multicentre study. Qual Life Res., 24,2895–2906. DOI: 10.1007/s11136-015-1039-y
  • Kurt, S., & Unsar, S. (2011). Assessment of symptom control in patients with cancer in Northwestern Turkey. Eur J Oncol Nurs., 15(2),137-44. https://doi.org/10.1016/j.ejon.2010.07.004
  • Lepretre, S., Touboul, C., Flinois, A., Kutikova, L., Makhloufi, K., Chauny, J-V., & Désaméricq, G., (2019). Quality of life impairment in adult patients with acute lymphoblastic leukemia with minimal residual disease in France. Blood, 134 (Supplement_1), 5123. http://doi.org/10.1182/blood-2019-122466.
  • Leukemia & Lymphoma Society (2020). Facts and Statistics. https://www.lls.org/facts-and-statistics/facts-and-statistics-overview/facts-and-statistics#Leukemia (accessed 07.07.2020).
  • Levin, T.T., Li Y., Riskind, J., & Rai, K.(2007). Depression, anxiety and quality of life in a Chronic Lymphocytic Leukemia cohort. General Hospital Psychiatry, 29,251-256. DOI:10.1016/j.genhosppsych.2007.01.014
  • Liao, Y-C., Shun, S-C., Liao, W-Y., Yu, C-J., Yang, P-C., & Lai, Y-H. (2014). Quality of life and related factors in patients with newly diagnosed advanced lung cancer: a longitudinal study. Oncology Nursing Forum, 41(2), E44–E55. doi:10.1188/14.ONF.E44-E55.
  • Malik, M., MPhil, I.R., & Hussain, A. (2021). Health related quality of life among blood cancer patients in Pakistan: A cross sectional survey. The Journal of Health Care Organization, Provision, and Financing, 58, 1-6. https://doi.org/10.1177/00469580211025211.
  • Mierzynska, J., Taye, M., Pe, M., Coens, C., Martinelli, F., Pogoda, K., Velikova, G., Bjelic-Radisic, V., Cardoso, F., Brain, E., Ignatiadis M., Piccart, M., Van Tienhoven, G., Mansel R., Wildiers H., Bottomley, A., on behalf of EORTC and EORTC Breast Cancer Group (2020). Reference values for the EORTC QLQ-C30 in early and metastatic breast cancer. European Journal of Cancer, 125,69-72. https://doi.org/10.1016/j.ejca.2019.10.031
  • Ministry of Health General Directorate of Public Health (2019). Cancer Statistics Turkey. Turkey Republic Ministry of Health General Directorate of Public Health, Ankara.
  • Molica, S. (2005). Quality of life in chronic lymphocytic leukemia: A neglected issue. Leukemia & Lymphoma, 46(12),1709–1714. DOI:10.1080/10428190500244183
  • Ng, C.G., Mohamed, S., See, M.H., Harun, F., Dahlui, M., Sulaiman, A.H., Zainal, N.Z., Taib, N.A., & on behalf of the MyBCC Study group. (2015). Anxiety, depression, perceived social support and quality of life in Malaysian breast cancer patients: a 1-year prospective study. Health and Quality of Life Outcomes, 13(205),1-9. DOI: 10.1186/s12955-015-0401-7.
  • Oh, G.H., Yeom, C-W., Shim, E-J., Jung, D., Lee, K-M., Son, K-L., Kim, W-H., Moon, J.Y., Jung, S., Kim, T-Y., Im, S-A., Lee, K-H., & Hahm, B-J. (2020). The effect of perceived social support on chemotherapy-related symptoms in patients with breast cancer: A prospective observational study. Journal of Psychosomatic Research, 130,1-31. https://doi.org/10.1016/j.jpsychores.2019.109911.
  • Pamuk, E.G., Harmandar, F., Ermantaş, N., Harmandar, O., Turgut, B., Demir, M., & Vural, Ö. (2008). EORTC QLQ-C30 Assessment in Turkish Patients with Hematological Malignancies. Annals Hematology, 87,305-310. DOI: 10.1007/s00277-008-0445-4
  • Pashos, C.L., Flowers, C.R., Kay, N.E., Weiss, M., Lamanna, N., Farber, C., Lerner, S., Sharrman, J., Grinblatt, D., Flinn, I.W., Kozloff, M., Swern, A.S., Street, T.K., Sulliavan, K.A., Harding, G., & Khan, Z.M. (2013). Association of health-related quality of life with gender in patients with B-cell chronic lymphocytic leukemia. Support Care Cancer, 21, 2853-2860. DOI 10.1007/s00520-013-1854-z.
  • Sacha, T., Góra-Tybor, J., Wąsak-Szulkowska, E., Kyrcz-Krzemień, S., Mędraś, E., Becht, R., Bober, G., Kotowska, A., Wącław, J., & Hellmann, A. (2017). Quality of life and adherence to therapy in patients with Chronic Myeloid Leukemia treated with Nilotinib as a second-line therapy: A Multicenter prospective observational study. Clinical Lymphoma, Myeloma & Leukemia, 17(5),283-95. http://dx.doi.org/10.1016/j.clml.2017.01.001
  • Santos, F.R.M., Kozasa, E.H., de Lourdes, L F Chauffaille, M., Colleoni, G.W.B., & Leite, J.R. (2006). Psychosocial adaptation and quality of life among Brazilian patients with different hematological malignancies. Journal of Psychosomatic Research, 60,505-511. DOI:10.1016/j.jpsychores.2005.08.017
  • Savcı, A.B. (2006). The factors effecting quality of life and the level of social support in cancer patients. (Unpublished master's thesis). Ataturk University, Health Science Institute, Department of Public Health, Erzurum, Turkey.
  • Schumacher, A., Wewers, D., Heinecke, A., Sauerland, C., Koch, O. M., van de Loo, J., Büchner, T., & Berdel, W.E. (2002). Fatigue as an important aspect of quality of life in patients with acute myeloid leukemia. Leukemia Research, 26(4),355–362. doi:10.1016/s0145-2126(01)00145-x
  • Shanafelt, T.D., Bowen, D.A., Venkat, C., Slager, S.L., Zent, C.S., Kay, N.E., Reinalda, M., Tun, H., Sloan, J.A., & Call, T.G. (2009). The physician–patient relationship and quality of life: Lessons from chronic lymphocytic leukemia. Leukemia Research, 33(2),263–270. DOI:10.1016/j.leukres.2008.06.019
  • Shaulov, A., Rodin, G., Popovic, G., Caraiscos, V.B., Le, L.W., Rydall, A., Schimmer, A.D., & Zimmermann, C. (2019). Pain in patients with newly diagnosed or relapsed acute leukemia. Supportive Care in Cancer, 27, 2789-2797. https://doi.org/10.1007/s00520-018-4583-5.
  • Sprangers, M., Cull A., Bjordal, K., Groenvold, M., Aaronson, N.K., & for the EORTC Study Group on Quality of Life (1993). The European Organization for Research and Treatment of Cancer approach to quality of life assessment: Guidelines for developing questionaire modules. Quality of Life Research, 2,287-295. DOI: 10.1023/a:1024977728719.
  • Straus, S.E., Glasziou, P., Richardson, W.S., & Haynes, R.B. (2018). Evidence-based medicine: how to practice and teach EBM. (5th Ed). Edinburgh: UK: Elsevier Churchill Livingstone. ISBN: 0702062960,9780702062964
  • Tawfik, B., Pardee, T.S., Isom, S., Sliesoraitis, S., Winter, A., Lawrence, J., Powell, B.L., & Klepin, H.D. (2016). Comorbidity, age, and mortality among adults treated intensively for acute myeloid leukemia (AML). Journal of Geriatric Oncology, 7(1),24–31. DOI:10.1016/j.jgo.2015.10.182
  • Tinsley, S.M., Sutton, S.K., Thapa, R., Lancet, J., & McMillan, S.C. (2017). Treatment choices: A quality of life comparison in Acute Myeloid Leukemia and high-risk Myelodysplastic Syndrome. Clinical Lymphoma, Myeloma & Leukemia, 17(S1),S75-9. http://dx.doi.org/10.1016/j.clml.2017.02.016
  • Wang, C., Chen, J., Wang, Y., Xu, W., Xie, M., Wu, Y., & Hu, R. (2021). Effects of family participatory dignity therapy on the psychological well-being and family function of patients with haematologic malignancies and their family caregivers: A randomised controlled trial. International Journal of Nursing Studies, 118(103922), 1-13. https://doi.org/10.1016/j.ijnurstu.2021.103922.
  • Waweru, C., Kaur, S., Sharma, S., & Mishra, N. (2019). Health-Related quality of life and economic burden in Chronic Lymphocytic Leukemia. Blood, 134(1), 5812. http://doi.org/10.1182/blood-2019-125909.
  • World Health Organization [WHO] (2018). Cancer. https://www.who.int/news-room/fact-sheets/detail/cancer (accessed 07.07.2020).
  • Yun, Y.H., Park Y.S., Lee, E.S., Bang, S-M., Heo, D.S., Park, S.Y., You, C.H. & West, K. (2004). Validation of the Korean version of the EORTC QLQ-C30. Quality of Life Research, 13(4), 863-868. http://www.jstor.org/stable/4038926
  • Zeng, X., Sui, M., Liu, R., Qian, X., Li W., Zheng, E., Yang, J., Li. J., Huang, W., Yang, H., Yu, H., & Luo, N. (2021). Assessment of the health utility of patients with leukemia in China. Health and Quality of Life Outcomes, 19(65), 1-9. https://doi.org/10.1186/s12955-021-01711-1.
  • Zimet, G.D., Dahlem, N.W., Zimet, S.G., & Farley, G.K. (1988). The Multidimensional Scale of Perceived Social Support. Journal of Personality Assessment, 52(1),30-41. DOI: 10.1207/s15327752jpa5201_2
  • Zimmermann, C., Yuen, D., Mischitelle, A., Minden, M.A., Brandwein, J.M., Schimmer, A., Gagliese, L., Lo C., Rydall, A. & Rodin, G. (2013). Symptom burden and supportive care in patients with acute leukemia. Leukemia Research, 37,731– 736. http://dx.doi.org/10.1016/j.leukres.2013.02.009

Lösemili Hastaların Yaşam Kalitesi ve Sosyal Destek Düzeylerinin Değerlendirilmesi

Yıl 2021, Cilt: 3 Sayı: 3, 200 - 214, 25.12.2021

Öz

Amaç: Bu çalışma, lösemi hastaların yaşam kalitesi, sosyal destek düzeyleri ve etkileyen faktörleri belirlemek amacıyla planlandı.
Yöntem: Tanımlayıcı-kesitsel tipteki bu çalışmaya İstanbul ilinde bir Tıp Fakültesi Hastanesi Hematoloji Polikliniğine başvuran 117 lösemi hastası dahil edildi. Verilerin toplanması için Hasta Bilgi Formu, European Organization fort the Reseach and Treatment of Cancer Quality of Questionnaire – Core 30 (EORTC QLQ-C30) ve Çok Boyutlu Algılanan Sosyal Destek Düzeyi (ÇBASDD) ölçeğinden oluşan bir form kullanıldı. Verilerin analizinde normallik analizi, betimleyici istatistikler, ikili ve çoklu grupların arasındaki fark analizleri ve korelasyon analizi kullanıldı.
Bulgular: Bu çalışmada lösemili hastaların genel yaşam kalitesi, fonksiyonel ölçekler ve semptom ölçekleri yaş, cinsiyet, çocuk sayısı, BKİ, medeni durum, eğitim durumu, löseminin türü, hastalığa uyum sağlama durumu, hastalığın teşhis edilmesi ve tedavi süresi gibi kişisel ve hastalıkla ilgili özelliklerden etkilendiği belirlendi (p<0,05). ÇBASDD ölçeği toplam ve alt boyutları ile EORTC QLQ-C30 yaşam kalitesi ölçeğinin genel yaşam kalitesi ve fonksiyonel ölçekleri ile pozitif yönde ve iştahsızlık semptomu ve mali zorluk maddesiyle negatif yönde anlamlı bir ilişki olduğu belirlendi (p<0,05).
Sonuç ve Öneriler: Sonuç olarak hemşirelerin lösemi hastalarının yaşam kalitesini ve sosyal destek düzeylerini etkileyen kişisel ve hastalığa ilişkin özellikleri göz önüne alarak holistik bir bakım sunması hastaların yaşam kalitesi ve sosyal destek düzeylerini iyileştireceği düşünülmektedir.

Proje Numarası

Yok

Kaynakça

  • Aaronson, N.K., Ahmedzai, S.A., Bergman, B., Bullinger, M., Cull, A., Duez, N.J., Filiberti, A., Flechtner, H., Fleishman, S.B., de Haes, J.C.J.M., Kaasa, S., Klee, M., Osoba, D., Razavi, D., Rofe, P.B., Schraub, S., Sneeuw, K., Sullivan, M., et al. (1993). The European Organization for Research and Treatment of Cancer QLQ-C30: A quality-of-life instrument for use in international clinical trials in oncology. Journal of National Cancer Institute, 85(5), 365-376. https://doi.org/10.1093/jnci/85.5.365.
  • Albercht, T.A., & Bryant, A.L. (2019). Psychological and financial distress managementin adults with acute leukemia. Seminars in Oncology Nursing, 35(6),150952. DOI: 10.1016/j.soncn.2019.150952.
  • AlFayyad, I., Al-Tannir, M., Yaqub, M., Heena, H., AlMukaibil, N., Ghazwani, M., Abu-Shaheen, A. (2020). Clinically significant fatigue in adult leukemia patients: Prevalence, predictors, and ımpact on quality of life. Cureus, 12(12), e12245. DOI 10.7759/cureus.12245.
  • Alibhai, S. M. H., Leach, M., Kermalli, H., Gupta, V., Kowgier, M. E., Tomlinson, G. A., Brandwein, J., Buckstein, R. & Minden, M. D. (2007). The impact of acute myeloid leukemia and its treatment on quality of life and functional status in older adults. Critical Reviews in Oncology/Hematology, 64(1), 19–30. DOI:10.1016/j.critrevonc.2007.07.003.
  • Altmore, I., Gerds, A.T., Lessen, D., Colucci, P., Parasuraman BPharm S., Chamikara Paranagama, D., & Mesa, R.A. (2018). Correlation between MPN-SAF TSS and EORTC QLQ-C30 scores in patients with PV: Data from the reveal study. Blood, 132(Supplement 1), 2259. https://doi.org/10.1182/blood-2018-99-112937.
  • American Cancer Society (2019). Cancer Facts & Figures 2019. https://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2019/cancer-facts-and-figures-2019.pdf ET: 07.07.2020.
  • Ayaz, S., Yaman Efe, Ş. & Korukluoğlu, S. (2008). Level of perceived social support of patients with gynaecological cancer and affecting factors. Turkiye Klinikleri J Med Sci. 28(6),880-885. https://www.turkiyeklinikleri.com/article/en-jinekolojik-kanserli-hastalarin-algiladiklari-sosyal-destek-duzeyleri-ve-etkileyen-faktorler-52677.html
  • Aydın Bektaş, H. & Akdemir, N. (2006). The assessment of functional status in individual's who have cancer. Turkiye Klinikleri J Med Sci. 26(5):488-499. https://www.turkiyeklinikleri.com/article/en-kanserli-bireylerin-fonksiyonel-durumlarinin-degerlendirilmesi-46538.html
  • Bakan, B.A., & Guraksin, A. (2017). Factors affecting quality of life and level social support in cancer patients. Belitung Nursing Journal, 3(2), 54-64. https://doi.org/10.33546/bnj.48
  • Beser, N., & Öz, F. (2003). Kemoterapi alan Lenfomalı hastaların anksiyete-depresyon düzeyleri ve yaşam kalitesi. C.Ü. Hemşirelik Yüksek Okulu Dergisi, 7(1),47-58. http://eskidergi.cumhuriyet.edu.tr/makale/623.pdf
  • Bjordal, K., de Graeff, A., Fayers, P.M., Hammerlid, E., van Pottelsberghe, C., Curran, D., Ahlner-Elmqvist, M., Maher, E.J., Meyza, J.W., Brédart, A., Söderholm, A.L., Arraras, J.J., Feine, J.S., Abendstein, H., Morton, R.P., Pignon, T., Huguenin, P., Bottomly, A., Kaasa, S. & on behalf of the EORTC Quality of Life Group (2000). A 12 country field study of the EORTC QLQ-C30 (version 3.0) and the head and neck cancer specific module (The EORTC QLQ-H&N35). European Journal of Cancer, 36,213-219. DOI: 10.1016/s0959-8049(00)00186-6.
  • Borregaard Myrhøja, C., Holmegaard Nørskova, K., Jarden, M., & Rydahl-Hansen, S. (2020). The motivation to volunteer as a peer support provider to newly diagnosed patients with acute leukemia – A qualitative interview study. European Journal of Oncology Nursing, 46 (1017509, 1-6. https://doi.org/10.1016/j.ejon.2020.101750.
  • Bosshard, R., O’Reilly, K., Ralston S., Chadda, S., & Cork, D. (2018). Systematic reviews of economic burden and health-related quality of life in patients with acute myeloid leukemia. Cancer Treatment Reviews, 69, 224-232. https://doi.org/10.1016/j.ctrv.2018.07.005.
  • Buckley, S. A., Othus, M., Vainstein, V., Abkowitz, J. L., Estey, E. H., & Walter, R. B. (2014). Prediction of adverse events during intensive induction chemotherapy for acute myeloid leukemia or high-grade myelodysplastic syndromes. American Journal of Hematology, 89(4),423–428. DOI:10.1002/ajh.23661
  • Cella, D., Jensen, S.E., Webster, K., Du, H., Lai, J-S., Rosen, S., Tallman, M.S., & Yount, S. (2012). measuring health-related quality of Life in leukemia: The Functional Assessment of Cancer Therapy–Leukemia (FACT-Leu) questionnaire. value in health, 15(8),1051-1058. http://dx.doi.org/10.1016/j.jval.2012.08.2210
  • Cohen, J. (1992). Statistical Power Analysis. Current Directions in Psychological Science, 1(3), 98–101. doi:10.1111/1467-8721.ep10768783.
  • Craveiro, D. (2017). The role of personal social networks on health inequalities across European regions. Health & Place, 45,24–31. http://dx.doi.org/10.1016/j.healthplace.2017.02.007
  • Çalışkan, T., Duran, S., Karadaş, A., Ergün, S., & Tekir, Ö. (2015). Assessment the levels of life quality and social support of the cancer patients. Kırıkkale Üniversitesi Tıp Fakültesi Dergisi, 17(1), 27-36. https://dergipark.org.tr/tr/pub/kutfd/issue/10160/124910
  • Dziura, J.D., Post, L.A., Zhao, Q., Fu, Z., & Peduzzi, P. (2013). Strategies for dealing with missing data in clinical trials: from design to analysis. Yale Journal of Biology And Medicine 86, 343-358. PMC3767219. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767219/#R47
  • Efficace, F., Baccarani, M., Breccia, M., Alimena, G., Rosti, G., Cottone, F., Castagnetti, F., Lambertenghi Deliliers, G., Russo Rossi, A., Pardini, S., Gherlinzoni, F., Salvucci, M., Tiribelli, M., Vignetti, M., & Mandelli, F. (2011). Investigating personal and treatment related factors associated with adherence behavior in patients with chronic myeloid leukemia receiving long term Imatinib therapy. Blood, 118 (21), 1026. http://doi.org/10.1182/blood.V118.21.1026.1026.
  • Efficace, F., Cottone, F., Sommer, K., Kieffer, J., Aaronson, N., Fayers, P., Groenvold, M., Caocci, G., Lo Coco, F., Gaidano, G., Niscola, P., Baccarani, M., Rosti, G., Venditti, A., Emanuele, A., Fazi, P., Vignetti, M., & Giesinger, J., (2019). Validation of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Core 30 summary score in patients with hematologic malignancies. Value Health, 22(11), 1303-1310. https://doi.org/10.1016/j.jval.2019.06.004.
  • Eker, D., & Arkar, H. (1995). Çok Boyutlu Algılanan Sosyal Destek Ölçeğinin Faktör Yapısı, Geçerlilik ve Güvenirliği. Turkish Journal of Psychology, 10(34),45-55. https://www.psikolog.org.tr/tr/yayinlar/dergiler/1031828/tpd1300443319950000m000290.pdf
  • Eker, D., Arkar, H., & Yaldız, H. (2001). Factorial structure, validity, and reliability of revised form of the Multidimensional Scale of Perceived Social Support. Turkish Journal of Psychiatry, 12(1),17-25. http://www.turkpsikiyatri.com/c12s1/cokboyutlualgilanan.pdf
  • El-Jawahri, A., waldman, L., Greer, J., Abel G.A., Steensma, D.P., Brunner, A.M., Fathi, A.T., DeAngelo, D.J., Wadleigh, M., Hobbs, G.S., Amrein, P.C., Stone, R.M., & Temel, J.S. (2018). Quality of life and psychological distress in patients with Acute Myeloid Leukemia (AML). Blood, 132(1), 2291. http://doi.org/10.1182/blood-2018-99-114246.
  • Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007). G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39, 175-191. doi: 10.3758/bf03193146.
  • Fayers, P.M., Aaronson, N.K., Bjordal, K., Groenvold, M., Curran, D., Bottomley, A., & on behalf of the EORTC Quality of Life Group (2001). The EORTC QLQ-C30 Scoring Manual (3rd Edition). Published by: European Organisation for Research and Treatment of Cancer, Brussels. https://www.eortc.be/qol/files/SCManualQLQ-C30.pdf.
  • Guzelant, A., Goksel, T., Ozkok, S., Tasbakan, S., Aysan, T., & Bottomley, A. (2004). The European Organization for Research and Treatment of Cancer QLQ-C30: an Examination into the cultural validity and reliability of the Turkish version of the EORTC QLQ-C30. European Journal of Cancer Care, 13,135-144. DOI: 10.1111/j.1365-2354.2003.00435.x.
  • Han, A., & Choi, J.S. (2018). Factors influencing infection prevention self-care behaviors in patients with hematologic cancer after discharge. European Journal off Oncology Nursing, 35,102-106. https://doi.org/10.1016/j.ejon.2018.06.005.
  • Herschbach, P., Keller, M., Knight, L., Brandl, T., Huber, B., Henrich, G., & Marten-Mittag, B. (2004) Psychological problems of cancer patients: a cancer distress screening with a cancer-specific questionnaire. British Journal of Cancer 91, 504–511. https://doi.org/10.1038/sj.bjc.6601986
  • Henriques, A., Silva, S., Severo, M., Fraga,, S., & Barros, H. (2020). Socioeconomic position and quality of life among older people: The mediating role of social support. Preventive Medicine, 135,1-6. https://doi.org/10.1016/j.ypmed.2020.106073
  • Hensel, M., Egerer, G., Schneeweiss, A., Goldschmidt, H., & Ho, A. D. (2002). Quality of life and rehabilitation in social and professional life after autologous stem cell transplantation. Annals of Oncology, 13(2), 209–217. doi:10.1093/annonc/mdf031
  • Holmegaard Nørskov, K., Overgaard, D., Lomborg, K., Kjeldsen, L., & Jarden, M. (2019). Patients experiences and social support needs following the diagnosis and initial treatment of acute leukemia - A qualitative study. European Journal of Oncology Nursing, 41,49-55. DOI:10.1016/j.ejon.2019.05.005
  • Holtzer-Goor, K.M., Schaafsma, M.R., Joosten, P., Posthuma, E.F.M., Wittebol, S., Huijgens, P.C., Mattijssen, E.J.M., Vreugdenhil, G., Visser, H., Peters, W.G., Erjavec, Z., Wijermans, P.W., Daenen, S.M.G.J., van der Hem, K.G., van Oers, M.H.J. & Uyl-de Groot, C.A. (2015). Quality of life of patients with chronic lymphocytic leukaemia in the Netherlands: results of a longitudinal multicentre study. Qual Life Res., 24,2895–2906. DOI: 10.1007/s11136-015-1039-y
  • Kurt, S., & Unsar, S. (2011). Assessment of symptom control in patients with cancer in Northwestern Turkey. Eur J Oncol Nurs., 15(2),137-44. https://doi.org/10.1016/j.ejon.2010.07.004
  • Lepretre, S., Touboul, C., Flinois, A., Kutikova, L., Makhloufi, K., Chauny, J-V., & Désaméricq, G., (2019). Quality of life impairment in adult patients with acute lymphoblastic leukemia with minimal residual disease in France. Blood, 134 (Supplement_1), 5123. http://doi.org/10.1182/blood-2019-122466.
  • Leukemia & Lymphoma Society (2020). Facts and Statistics. https://www.lls.org/facts-and-statistics/facts-and-statistics-overview/facts-and-statistics#Leukemia (accessed 07.07.2020).
  • Levin, T.T., Li Y., Riskind, J., & Rai, K.(2007). Depression, anxiety and quality of life in a Chronic Lymphocytic Leukemia cohort. General Hospital Psychiatry, 29,251-256. DOI:10.1016/j.genhosppsych.2007.01.014
  • Liao, Y-C., Shun, S-C., Liao, W-Y., Yu, C-J., Yang, P-C., & Lai, Y-H. (2014). Quality of life and related factors in patients with newly diagnosed advanced lung cancer: a longitudinal study. Oncology Nursing Forum, 41(2), E44–E55. doi:10.1188/14.ONF.E44-E55.
  • Malik, M., MPhil, I.R., & Hussain, A. (2021). Health related quality of life among blood cancer patients in Pakistan: A cross sectional survey. The Journal of Health Care Organization, Provision, and Financing, 58, 1-6. https://doi.org/10.1177/00469580211025211.
  • Mierzynska, J., Taye, M., Pe, M., Coens, C., Martinelli, F., Pogoda, K., Velikova, G., Bjelic-Radisic, V., Cardoso, F., Brain, E., Ignatiadis M., Piccart, M., Van Tienhoven, G., Mansel R., Wildiers H., Bottomley, A., on behalf of EORTC and EORTC Breast Cancer Group (2020). Reference values for the EORTC QLQ-C30 in early and metastatic breast cancer. European Journal of Cancer, 125,69-72. https://doi.org/10.1016/j.ejca.2019.10.031
  • Ministry of Health General Directorate of Public Health (2019). Cancer Statistics Turkey. Turkey Republic Ministry of Health General Directorate of Public Health, Ankara.
  • Molica, S. (2005). Quality of life in chronic lymphocytic leukemia: A neglected issue. Leukemia & Lymphoma, 46(12),1709–1714. DOI:10.1080/10428190500244183
  • Ng, C.G., Mohamed, S., See, M.H., Harun, F., Dahlui, M., Sulaiman, A.H., Zainal, N.Z., Taib, N.A., & on behalf of the MyBCC Study group. (2015). Anxiety, depression, perceived social support and quality of life in Malaysian breast cancer patients: a 1-year prospective study. Health and Quality of Life Outcomes, 13(205),1-9. DOI: 10.1186/s12955-015-0401-7.
  • Oh, G.H., Yeom, C-W., Shim, E-J., Jung, D., Lee, K-M., Son, K-L., Kim, W-H., Moon, J.Y., Jung, S., Kim, T-Y., Im, S-A., Lee, K-H., & Hahm, B-J. (2020). The effect of perceived social support on chemotherapy-related symptoms in patients with breast cancer: A prospective observational study. Journal of Psychosomatic Research, 130,1-31. https://doi.org/10.1016/j.jpsychores.2019.109911.
  • Pamuk, E.G., Harmandar, F., Ermantaş, N., Harmandar, O., Turgut, B., Demir, M., & Vural, Ö. (2008). EORTC QLQ-C30 Assessment in Turkish Patients with Hematological Malignancies. Annals Hematology, 87,305-310. DOI: 10.1007/s00277-008-0445-4
  • Pashos, C.L., Flowers, C.R., Kay, N.E., Weiss, M., Lamanna, N., Farber, C., Lerner, S., Sharrman, J., Grinblatt, D., Flinn, I.W., Kozloff, M., Swern, A.S., Street, T.K., Sulliavan, K.A., Harding, G., & Khan, Z.M. (2013). Association of health-related quality of life with gender in patients with B-cell chronic lymphocytic leukemia. Support Care Cancer, 21, 2853-2860. DOI 10.1007/s00520-013-1854-z.
  • Sacha, T., Góra-Tybor, J., Wąsak-Szulkowska, E., Kyrcz-Krzemień, S., Mędraś, E., Becht, R., Bober, G., Kotowska, A., Wącław, J., & Hellmann, A. (2017). Quality of life and adherence to therapy in patients with Chronic Myeloid Leukemia treated with Nilotinib as a second-line therapy: A Multicenter prospective observational study. Clinical Lymphoma, Myeloma & Leukemia, 17(5),283-95. http://dx.doi.org/10.1016/j.clml.2017.01.001
  • Santos, F.R.M., Kozasa, E.H., de Lourdes, L F Chauffaille, M., Colleoni, G.W.B., & Leite, J.R. (2006). Psychosocial adaptation and quality of life among Brazilian patients with different hematological malignancies. Journal of Psychosomatic Research, 60,505-511. DOI:10.1016/j.jpsychores.2005.08.017
  • Savcı, A.B. (2006). The factors effecting quality of life and the level of social support in cancer patients. (Unpublished master's thesis). Ataturk University, Health Science Institute, Department of Public Health, Erzurum, Turkey.
  • Schumacher, A., Wewers, D., Heinecke, A., Sauerland, C., Koch, O. M., van de Loo, J., Büchner, T., & Berdel, W.E. (2002). Fatigue as an important aspect of quality of life in patients with acute myeloid leukemia. Leukemia Research, 26(4),355–362. doi:10.1016/s0145-2126(01)00145-x
  • Shanafelt, T.D., Bowen, D.A., Venkat, C., Slager, S.L., Zent, C.S., Kay, N.E., Reinalda, M., Tun, H., Sloan, J.A., & Call, T.G. (2009). The physician–patient relationship and quality of life: Lessons from chronic lymphocytic leukemia. Leukemia Research, 33(2),263–270. DOI:10.1016/j.leukres.2008.06.019
  • Shaulov, A., Rodin, G., Popovic, G., Caraiscos, V.B., Le, L.W., Rydall, A., Schimmer, A.D., & Zimmermann, C. (2019). Pain in patients with newly diagnosed or relapsed acute leukemia. Supportive Care in Cancer, 27, 2789-2797. https://doi.org/10.1007/s00520-018-4583-5.
  • Sprangers, M., Cull A., Bjordal, K., Groenvold, M., Aaronson, N.K., & for the EORTC Study Group on Quality of Life (1993). The European Organization for Research and Treatment of Cancer approach to quality of life assessment: Guidelines for developing questionaire modules. Quality of Life Research, 2,287-295. DOI: 10.1023/a:1024977728719.
  • Straus, S.E., Glasziou, P., Richardson, W.S., & Haynes, R.B. (2018). Evidence-based medicine: how to practice and teach EBM. (5th Ed). Edinburgh: UK: Elsevier Churchill Livingstone. ISBN: 0702062960,9780702062964
  • Tawfik, B., Pardee, T.S., Isom, S., Sliesoraitis, S., Winter, A., Lawrence, J., Powell, B.L., & Klepin, H.D. (2016). Comorbidity, age, and mortality among adults treated intensively for acute myeloid leukemia (AML). Journal of Geriatric Oncology, 7(1),24–31. DOI:10.1016/j.jgo.2015.10.182
  • Tinsley, S.M., Sutton, S.K., Thapa, R., Lancet, J., & McMillan, S.C. (2017). Treatment choices: A quality of life comparison in Acute Myeloid Leukemia and high-risk Myelodysplastic Syndrome. Clinical Lymphoma, Myeloma & Leukemia, 17(S1),S75-9. http://dx.doi.org/10.1016/j.clml.2017.02.016
  • Wang, C., Chen, J., Wang, Y., Xu, W., Xie, M., Wu, Y., & Hu, R. (2021). Effects of family participatory dignity therapy on the psychological well-being and family function of patients with haematologic malignancies and their family caregivers: A randomised controlled trial. International Journal of Nursing Studies, 118(103922), 1-13. https://doi.org/10.1016/j.ijnurstu.2021.103922.
  • Waweru, C., Kaur, S., Sharma, S., & Mishra, N. (2019). Health-Related quality of life and economic burden in Chronic Lymphocytic Leukemia. Blood, 134(1), 5812. http://doi.org/10.1182/blood-2019-125909.
  • World Health Organization [WHO] (2018). Cancer. https://www.who.int/news-room/fact-sheets/detail/cancer (accessed 07.07.2020).
  • Yun, Y.H., Park Y.S., Lee, E.S., Bang, S-M., Heo, D.S., Park, S.Y., You, C.H. & West, K. (2004). Validation of the Korean version of the EORTC QLQ-C30. Quality of Life Research, 13(4), 863-868. http://www.jstor.org/stable/4038926
  • Zeng, X., Sui, M., Liu, R., Qian, X., Li W., Zheng, E., Yang, J., Li. J., Huang, W., Yang, H., Yu, H., & Luo, N. (2021). Assessment of the health utility of patients with leukemia in China. Health and Quality of Life Outcomes, 19(65), 1-9. https://doi.org/10.1186/s12955-021-01711-1.
  • Zimet, G.D., Dahlem, N.W., Zimet, S.G., & Farley, G.K. (1988). The Multidimensional Scale of Perceived Social Support. Journal of Personality Assessment, 52(1),30-41. DOI: 10.1207/s15327752jpa5201_2
  • Zimmermann, C., Yuen, D., Mischitelle, A., Minden, M.A., Brandwein, J.M., Schimmer, A., Gagliese, L., Lo C., Rydall, A. & Rodin, G. (2013). Symptom burden and supportive care in patients with acute leukemia. Leukemia Research, 37,731– 736. http://dx.doi.org/10.1016/j.leukres.2013.02.009
Toplam 63 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Sağlık Kurumları Yönetimi
Bölüm Araştırma Makaleleri
Yazarlar

Zülfiye Bıkmaz 0000-0003-3785-968X

Serap Ünsar 0000-0001-7723-8816

Proje Numarası Yok
Yayımlanma Tarihi 25 Aralık 2021
Gönderilme Tarihi 5 Şubat 2021
Kabul Tarihi 6 Eylül 2021
Yayımlandığı Sayı Yıl 2021 Cilt: 3 Sayı: 3

Kaynak Göster

APA Bıkmaz, Z., & Ünsar, S. (2021). Quality of Life and Social Support Levels in Leukemia Patients. Genel Sağlık Bilimleri Dergisi, 3(3), 200-214.

                                                                  Genel Sağlık Bilimleri Dergisi Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı (CC BY NC) ile lisanslanmıştır.