The Relationship Between Antropometric Measurements And Cord Blood Tenascin-C, Insulin And Glucose Levels In Diabetic Mother’s Babies

Öz

Aim: To investigate whether Tenascin-C has a role in the growth of a fetus affected from a chronic inflammatory process, diabetes and to determine cord blood Tenascin-C, insulin and glucose levels in infants of diabetic mothers.Material And Methods: Infants of diabetic mothers born at >376/7 weeks of gestation group 1, n=25 and healthy controls group 2, n=35 are included in this prospective study. Anthropometric measurements of infants height, head circumference, weight, chest circumference were recorded to assess their physical development. Cord blood levels of insulin, glucose and Tenascin-C were measured at birth.Results: Totally 25 infants of diabetic mothers and 35 healthy controls were included in the study. Cord blood Tenascin-C levels were significantly higher in infants of diabetic mothers when compared with healthy neonates p

Anahtar Kelimeler

• Diabetes,insulin,inflammation,newborn,Tenascin-C

Diyabetik Anne Bebeklerinde Antropometrik Ölçümler İle Kord Kanı Tenascin-C, İnsülin Ve Glikoz Seviyelerinin İlişkisi

Öz

Giriş: Bu çalışmada Kronik bir inflamatuar süreç olan diyabetten etkilenen fetüsün büyümesinde Tenascin-C’nin rolünün olup olmadığının araştırılması ve kord kanı Tenascin-C, insülin ve glikoz düzeylerinin karşılaştırılması amaçlanmıştır.Gereç ve Yöntemler: Bu prospektif çalışmaya gebelik haftası >376/7olan, diyabetik anne bebekleri grup 1, n=25 ile annesinde diyabet olmayan sağlıklı bebekler grup 2, n=35 dahil edildi. Bebeklerin boy, baş çevresi, tartı ve göğüs çevreleri aynı kişi tarafından ölçülüp kayıt edildi. Doğumda göbek kordonundan alınan kan örneğinden Tenascin-C, insülin, glikoz düzeyleri çalışıldı.Sonuçlar: Prenatal diyabet maruziyeti olan grup 1 ile sağlıklı yenidoğanlardan oluşan grup 2‘nin kord kanı Tenascin-C seviyeleri karşılaştırıldığında istatistiksel olarak anlamlı fark bulundu p

Anahtar Kelimeler

• Diyabet,insülin,inflamasyon,Tenascin-C,yenidoğan

Kaynakça

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