A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES

Canan Unal; Atakan Tanacan; Erdem Fadıloğlu; Nurhayat Halis; Murat Cagan; M.sinan Beksac

doi:10.38136/jgon.724384

A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES

Öz

Amaç: 40 yaşın üzerindeki spontan gebeliklerde olumsuz obstetrik ve neonatal sonuçları tahmin etmek için anne yaşı için bir eşik değer tanımlamak. Yöntem: 40 yaş ve üzeri 359 gebelik retrospektif olarak değerlendirildi. Gebeler grup 1 (40-43) ve grup 2 (≥44) olmak üzere iki gruba ayrıldı. Çalışma gruplarının obstetrik ve neonatal sonuçları karşılaştırıldı. Ayrıca maternal yaş açısından olumsuz obstetrik ve neonatal sonuçları tahmin etmek için ROC eğrisi analizi yapıldı. Bulgular: Obstetrik komplikasyon oranı grup 2'de (% 80.5) grup 1'den (% 36.5) anlamlı olarak daha yüksekti (p <0.001). Preeklampsi oranı da grup 2'de anlamlı olarak daha fazlaydı (p: 0.001). NICU'ya yatış oranları, grup 2'de (% 77.1) grup 1'e (% 28.7) göre istatistiksel olarak anlamlı derecede yüksekti (p <0.001). ROC eğrisi analizi, 41.5 yaşın olumsuz yenidoğan sonuçlarını ve NICU’ya ihtiyacı tahmin etmek için bir eşik değeri olarak bulundu (AUC: 0.607,0.566 sırasıyla). Sonuç: Doktorlar ileri anne yaşı gebeliklerinin yönetiminde özellikle ≥41,5 yaş grubunda olan annelerde daha dikkatli olmalıdırlar. Background: To define a cut off value for maternal age to predict adverse obstetric and neonatal outcomes in spontaneous pregnancies ≥40 years of age. Methods: We retrospectively evaluated 359 pregnant women ≥40 years of age. Patients were enrolled into two groups as Group 1 (40-43) and Group 2 (≥44). We compared the obstetric and neonatal adverse outcomes of the study groups. We also performed ROC curve analysis to predict adverse obstetric and neonatal outcomes in terms of maternal age. Results: Composite obstetric complication rate was significantly higher in group 2 (80.5%) than in group 1 (36.5%) (p < 0.001). Preeclampsia rate was also significantly more common in group 2 (p: 0.001). Admission to NICU was statistically significantly higher in group 2 (77.1%) compared to group 1 (28.7%) (p < 0.001). ROC curve analysis revealed 41.5 years of age as a cut-off value for predicting adverse neonatal outcomes and NICU admission (AUC: 0.607 and 0.566, respectively). Conclusion: Physicians should be cautious in the management of advence maternal age (AMA) pregnancies especially in patients with maternal age of ≥41.5 years.

Anahtar Kelimeler

Advanced maternal age,, adverse obstetric outcome,, adverse neonatal outcome,, high risk pregnancy,, pregnancy

Kaynakça

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Ayrıntılar

Birincil Dil

İngilizce

Konular

Kadın Hastalıkları ve Doğum

Bölüm

Araştırma Makalesi

Yazarlar

Canan Unal ^*
0000-0003-0881-2831
Türkiye

Atakan Tanacan
0000-0001-8209-8248
Türkiye

Erdem Fadıloğlu Bu kişi benim
0000-0001-7953-2517
Türkiye

Nurhayat Halis Bu kişi benim
0000-0003-0014-121X
Türkiye

Murat Cagan Bu kişi benim
0000-0003-0629-4401
Türkiye

M.sinan Beksac
0000-0001-6362-787X
Türkiye

Yayımlanma Tarihi

30 Eylül 2020

Gönderilme Tarihi

21 Nisan 2020

Kabul Tarihi

16 Mayıs 2020

Yayımlandığı Sayı

Yıl 2020 Cilt: 17 Sayı: 3

DOI

https://doi.org/10.38136/jgon.724384

IZ

https://izlik.org/JA44TS59NG

Kaynak Göster

RIS / Bibtex

APA

Unal, C., Tanacan, A., Fadıloğlu, E., Halis, N., Cagan, M., & Beksac, M. (2020). A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, 17(3), 446-449. https://doi.org/10.38136/jgon.724384

AMA

1.Unal C, Tanacan A, Fadıloğlu E, Halis N, Cagan M, Beksac M. A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES. JGON. 2020;17(3):446-449. doi:10.38136/jgon.724384

Chicago

Unal, Canan, Atakan Tanacan, Erdem Fadıloğlu, Nurhayat Halis, Murat Cagan, ve M.sinan Beksac. 2020. “A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES”. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 17 (3): 446-49. https://doi.org/10.38136/jgon.724384.

EndNote

Unal C, Tanacan A, Fadıloğlu E, Halis N, Cagan M, Beksac M (01 Eylül 2020) A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 17 3 446–449.

IEEE

[1]C. Unal, A. Tanacan, E. Fadıloğlu, N. Halis, M. Cagan, ve M. Beksac, “A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES”, JGON, c. 17, sy 3, ss. 446–449, Eyl. 2020, doi: 10.38136/jgon.724384.

ISNAD

Unal, Canan - Tanacan, Atakan - Fadıloğlu, Erdem - Halis, Nurhayat - Cagan, Murat - Beksac, M.sinan. “A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES”. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 17/3 (01 Eylül 2020): 446-449. https://doi.org/10.38136/jgon.724384.

JAMA

1.Unal C, Tanacan A, Fadıloğlu E, Halis N, Cagan M, Beksac M. A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES. JGON. 2020;17:446–449.

MLA

Unal, Canan, vd. “A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES”. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi, c. 17, sy 3, Eylül 2020, ss. 446-9, doi:10.38136/jgon.724384.

Vancouver

1.Canan Unal, Atakan Tanacan, Erdem Fadıloğlu, Nurhayat Halis, Murat Cagan, M.sinan Beksac. A CUT OFF VALUE FOR ADVANCED MATERNAL AGE IN PREDICTING ADVERSE OBSTETRIC AND NEONATAL OUTCOMES IN SPONTANEOUS PREGNANCIES. JGON. 01 Eylül 2020;17(3):446-9. doi:10.38136/jgon.724384