Yıl 2019, Cilt 16 , Sayı 4, Sayfalar 191 - 195 2019-12-31

Amaç: Endometrioma hastalarında serum 25-OH vitamin D ve 8-Hidroksi 2-deoksigunazin (8-OH2dG) seviyelerini karşılaştırmak, kist boyutu ile ilişkisini saptamak. Gereç ve Yöntemler: Çalışmaya endometrioma tanısı alan 54 hasta ile normal over dokusuna sahip 26 hasta kontrol grubu olarak dahil edildi. Serum örneklerinde 25-OH vitamin D ve 8-OH2dG seviyelerine bakıldı. Bulgular: Hasta ve kontrol grubu arasında yaş, gebelik, doğum sayısı ve vücut kitle indexi (VKI) bakımından farklılık yoktu. Hasta grubunun D vitamini düzeyi, kontrol grubuna göre anlamlı derecede düşüktü (p=0.001). Kisti bilateral olan hastalar ile, kisti unilateral olan hastalar arasında D vitamini düzeyleri bakımından anlamlı farklılık yoktu (p=0.39). Hasta grubunda 48 (%88.8), kontrol grubunda 11 (%42.3) hastada D vitamini seviyesi <30-microgr/L idi. Hasta grubunda, D vitamini düzeyi hipovitaminoz seviyede olan hastalarda ortalama endometrioma çapı 58,4±25,14 mm iken, D vitamini düzeyi normal saptanan hastalarda endometrioma çapı ise 35,33±18,26 mm idi. Hipovitaminoz D saptanan hastalarda kist çapı ile D vitamini düzeyleri arasında ters bir ilişki saptandı. İki grup arasında 8-OH2dG düzeyleri bakımından anlamlı farklılık yoktu (p>0.05). Sonuç: Endometrioma varlığı, kist çapı ve serum D vitamini düzeyleri arasında ters ilişki olmasına rağmen, serum 8-OH2dG düzeylerinde değişiklik yoktu. Bu durum, overyan endometriozisin patogenezinde hala belirsiz noktalar olduğunu göstermektedir.
Endometrioma, 25-OH vitamin D
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Birincil Dil en
Konular Kadın Hastalıkları ve Doğum
Bölüm Araştırma Makaleleri
Yazarlar

Orcid: 0000-0003-0396-5791
Yazar: Neslihan BAYRAMOĞLU TEPE (Sorumlu Yazar)
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Orcid: 0000-0002-9158-0009
Yazar: Özcan BALAT
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Orcid: 0000-0002-4191-1244
Yazar: Tanyeli GÜNEYLİGİL KAZAZ
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Orcid: 0000-0002-4922-7148
Yazar: Hüseyin Çağlayan OZCAN
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Orcid: 0000-0001-6821-4070
Yazar: Seyhun SUCU
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Orcid: 0000-0003-3836-2958
Yazar: Özge KÖMÜRCÜ KARUSERCİ
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Orcid: 0000-0002-0720-970X
Yazar: Mete Gürol UĞUR
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Orcid: 0000-0002-7820-6290
Yazar: Hilmi TAŞDEMİR
Kurum: FACULTY OF MEDICINE
Ülke: Turkey


Tarihler

Başvuru Tarihi : 27 Aralık 2019
Kabul Tarihi : 29 Aralık 2019
Yayımlanma Tarihi : 31 Aralık 2019

Bibtex @araştırma makalesi { jgon665911, journal = {Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi}, issn = {}, eissn = {2667-7849}, address = {Talatpaşa Bulvarı No 128, Hamamönü - ANKARA}, publisher = {T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi}, year = {2019}, volume = {16}, pages = {191 - 195}, doi = {}, title = {Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma?}, key = {cite}, author = {BAYRAMOĞLU TEPE, Neslihan and BALAT, Özcan and GÜNEYLİGİL, Tanyeli and OZCAN, Hüseyin and SUCU, Seyhun and KÖMÜRCÜ KARUSERCİ, Özge and UĞUR, Mete Gürol and TAŞDEMİR, Hilmi} }
APA BAYRAMOĞLU TEPE, N , BALAT, Ö , GÜNEYLİGİL, T , OZCAN, H , SUCU, S , KÖMÜRCÜ KARUSERCİ, Ö , UĞUR, M , TAŞDEMİR, H . (2019). Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma?. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi , 16 (4) , 191-195 . Retrieved from https://dergipark.org.tr/tr/pub/jgon/issue/51822/665911
MLA BAYRAMOĞLU TEPE, N , BALAT, Ö , GÜNEYLİGİL, T , OZCAN, H , SUCU, S , KÖMÜRCÜ KARUSERCİ, Ö , UĞUR, M , TAŞDEMİR, H . "Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma?". Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 16 (2019 ): 191-195 <https://dergipark.org.tr/tr/pub/jgon/issue/51822/665911>
Chicago BAYRAMOĞLU TEPE, N , BALAT, Ö , GÜNEYLİGİL, T , OZCAN, H , SUCU, S , KÖMÜRCÜ KARUSERCİ, Ö , UĞUR, M , TAŞDEMİR, H . "Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma?". Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 16 (2019 ): 191-195
RIS TY - JOUR T1 - Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma? AU - Neslihan BAYRAMOĞLU TEPE , Özcan BALAT , Tanyeli GÜNEYLİGİL KAZAZ , Hüseyin Çağlayan OZCAN , Seyhun SUCU , Özge KÖMÜRCÜ KARUSERCİ , Mete Gürol UĞUR , Hilmi TAŞDEMİR Y1 - 2019 PY - 2019 N1 - DO - T2 - Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi JF - Journal JO - JOR SP - 191 EP - 195 VL - 16 IS - 4 SN - -2667-7849 M3 - UR - Y2 - 2019 ER -
EndNote %0 Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma? %A Neslihan BAYRAMOĞLU TEPE , Özcan BALAT , Tanyeli GÜNEYLİGİL KAZAZ , Hüseyin Çağlayan OZCAN , Seyhun SUCU , Özge KÖMÜRCÜ KARUSERCİ , Mete Gürol UĞUR , Hilmi TAŞDEMİR %T Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma? %D 2019 %J Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi %P -2667-7849 %V 16 %N 4 %R %U
ISNAD BAYRAMOĞLU TEPE, Neslihan , BALAT, Özcan , GÜNEYLİGİL, Tanyeli , OZCAN, Hüseyin , SUCU, Seyhun , KÖMÜRCÜ KARUSERCİ, Özge , UĞUR, Mete Gürol , TAŞDEMİR, Hilmi . "Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma?". Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 16 / 4 (Aralık 2020): 191-195 .
AMA BAYRAMOĞLU TEPE N , BALAT Ö , GÜNEYLİGİL T , OZCAN H , SUCU S , KÖMÜRCÜ KARUSERCİ Ö , UĞUR M , TAŞDEMİR H . Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma?. JGON. 2019; 16(4): 191-195.
Vancouver BAYRAMOĞLU TEPE N , BALAT Ö , GÜNEYLİGİL T , OZCAN H , SUCU S , KÖMÜRCÜ KARUSERCİ Ö , UĞUR M , TAŞDEMİR H . Low Serum Vitamin D and Normal Serum 8-Hydroxy-2-Deoxyguanosine Levels in Endometrioma Patients: Is It a Dilemma?. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2019; 16(4): 195-191.