Yıl 2019, Cilt 16 , Sayı 4, Sayfalar 207 - 210 2019-12-31

Objective: In our study, we aimed to compare the hematological efficacy of intravenous and oral forms of iron treatment in clinically stable patients with moderate postpartum anemia. Material and Method: One hundred and eighty postpartum cases, who had pre-discharge hemoglobin evaluation levels between 8-9.5 g/dl, were allocated into two groups. The 1st group was treated with oral fe +2 (n = 127, 70.6%), and the other group was treated with intra venous ferric carboxymaltose (n = 53, % 29.4). Group 1 received oral iron treatment for aproximately 8 weeks. Also in Group 2, intra venous ferric carboxymaltose iron replacement was performed twice with 1 week intervals. Late postpartum (8 weeks after delivery) hemoglobin levels were collected and recorded. Findings: Difference between the group 1 and group 2 in terms of late postpartum maternal haemoglobin levels was found statistically significant (respectively, 10,52±1,26 g/dl vs 11,82±1,06 g/dl, P value 0,021). After intravenous treatment, increase rate of hemoglobin in group 2 was found statistically significant when comparing with of in group 2. (1,51±0,72 g/dl vs 2,90±0,46 g/dl, P value ˂0,01 ). Conclusion: Although clinical evaluations and stability of anemic postpartum cases are part of our overall treatment and patient follow-up approaches, moderate and deeper anemic cases should be treated with 3rd generation intravenous iron forms for rapid hematologic improvement. Amaç: Çalışmamızda, orta düzey postpartum anemisi olan ve klinik olarak stabil olan hastalarda intravenöz ve oral demir tedavi seçeneklerinin hematolojik etkinliğini karşılaştırmayı amaçladık. Materyal ve Metod: Doğum sonrası taburcu olmadan hemen önce hemoglobin değerlerini 8-9.5 gr/dl olan 180 postpartum olgu iki gruba ayrıldı. 1. grup oral fe +2 (n = 127, %70.6), diğer grup ise intravenöz ferrik karboksmaltoz (n = 53, %29.4) ile tedavi edildi. Grup 1 oral demir tedavisi yaklaşık 8 hafta aldı. Grup 2'ye 1 hafta ara ile iki kez intravenöz ferrik karboksmaltoz replasmanı yapıldı. Geç postpartum (doğumdan 8 hafta sonra) hemoglobin düzeyleri toplandı ve kaydedildi. Bulgular: Postpartum maternal hemoglobin seviyeleri açısından grup 1 ve grup 2 arasındaki fark istatistiksel olarak anlamlı bulunmuştur (sırasıyla, 10,52±1,26 g/dl, 11,82±1,06 g/dl, P değeri 0,021). Grup 2’ de intravenöz demir tedavisi sonrası hb seviyelerinde artış oranı grup 1’le karşılaştırıldığında anlamlı olarak yüksek bulunmuştur. (sırasıyla, 1,51±0,72 g/dl, 2,90±0,46 g/dl, P değeri ˂0,01 ). Sonuç: Anemik postpartum vakaların klinik değerlendirmeleri genel tedavi ve hasta takip yaklaşımlarımızın bir parçası olsada, orta ve derin anemik olgular hızlı hematolojik iyileşme için 3. jenerasyon intravenöz demir formları ile tedavi edilmelidir.
postpartum anemia, iron deficiency, iron preparations
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Birincil Dil en
Konular Kadın Hastalıkları ve Doğum
Bölüm Araştırma Makaleleri
Yazarlar

Orcid: 0000-0002-9300-7329
Yazar: Zeliha Cigdem DEMİREL GULER
Kurum: özel ankara koru hastanesi
Ülke: Turkey


Orcid: 0000-0002-2281-2347
Yazar: Aşkın Evren GÜLER (Sorumlu Yazar)
Kurum: özel ankara koru hastanesi
Ülke: Turkey


Orcid: 0000-0003-1436-6049
Yazar: Erhan AKTÜRK
Kurum: İSTANBUL ŞİŞLİ HAMİDİYE ETFAL EĞİTİM VE ARAŞTIRMA HASTANESİ
Ülke: Turkey


Orcid: 0000-0001-8232-4719
Yazar: Melahat ATASEVER
Kurum: GİRESUN RESEARCH CENTER
Ülke: Turkey


Tarihler

Başvuru Tarihi : 29 Aralık 2019
Kabul Tarihi : 31 Aralık 2019
Yayımlanma Tarihi : 31 Aralık 2019

Bibtex @araştırma makalesi { jgon667077, journal = {Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi}, issn = {}, eissn = {2667-7849}, address = {Talatpaşa Bulvarı No 128, Hamamönü - ANKARA}, publisher = {T.C. Sağlık Bakanlığı Ankara Şehir Hastanesi}, year = {2019}, volume = {16}, pages = {207 - 210}, doi = {}, title = {Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia}, key = {cite}, author = {DEMİREL, Zeliha and GÜLER, Aşkın Evren and AKTÜRK, Erhan and ATASEVER, Melahat} }
APA DEMİREL, Z , GÜLER, A , AKTÜRK, E , ATASEVER, M . (2019). Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi , 16 (4) , 207-210 . Retrieved from https://dergipark.org.tr/tr/pub/jgon/issue/51822/667077
MLA DEMİREL, Z , GÜLER, A , AKTÜRK, E , ATASEVER, M . "Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia". Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 16 (2019 ): 207-210 <https://dergipark.org.tr/tr/pub/jgon/issue/51822/667077>
Chicago DEMİREL, Z , GÜLER, A , AKTÜRK, E , ATASEVER, M . "Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia". Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 16 (2019 ): 207-210
RIS TY - JOUR T1 - Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia AU - Zeliha Cigdem DEMİREL GULER , Aşkın Evren GÜLER , Erhan AKTÜRK , Melahat ATASEVER Y1 - 2019 PY - 2019 N1 - DO - T2 - Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi JF - Journal JO - JOR SP - 207 EP - 210 VL - 16 IS - 4 SN - -2667-7849 M3 - UR - Y2 - 2019 ER -
EndNote %0 Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia %A Zeliha Cigdem DEMİREL GULER , Aşkın Evren GÜLER , Erhan AKTÜRK , Melahat ATASEVER %T Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia %D 2019 %J Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi %P -2667-7849 %V 16 %N 4 %R %U
ISNAD DEMİREL, Zeliha , GÜLER, Aşkın Evren , AKTÜRK, Erhan , ATASEVER, Melahat . "Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia". Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi 16 / 4 (Aralık 2020): 207-210 .
AMA DEMİREL Z , GÜLER A , AKTÜRK E , ATASEVER M . Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia. JGON. 2019; 16(4): 207-210.
Vancouver DEMİREL Z , GÜLER A , AKTÜRK E , ATASEVER M . Comparison of Intravenous Iron Infusion or Oral Iron for Treatment of Moderate Postpartum Anemia. Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi. 2019; 16(4): 210-207.