Thrombosis In Newborn

Yıl 2015, Cilt: 12 Sayı: 2, 97 - 100, 01.03.2015

Nilgün Altuntaş Emine Erdeniz Deniz Yılmaz Şeyda Seferoğlu Çiğdem Hacıfazlıoğlu Mehmet Fatih Kışlalı

Öz

Although thrombosis is a rarecondition in newborns, early diagnosis is important because of it’sserious morbidity. The knowledgerelated to managementstrategiesor the efficacy and safety of therapeuticagents is limited. In this paper, two cases with thrombosis who were treated with low- molecular –weight heparin successfully were reported.

Anahtar Kelimeler

Newborns, thrombosis

Yenidoğanda Tromboz

Öz

Yenidoğanda tromboz nadir görülmesine karşın ciddi morbiditesi nedeni ile erken tanı önemlidir. Yenidoğan döneminde tedavi yöntemleri ve terapötik ajanların etki ve güvenilirlikleri ile ilgili bilgi kısıtlıdır. Bu makalede düşük molekül ağırlıklı heparin ile başarılı şekilde tedavi edilen renal ven trombozlu ve serebral trombozlu iki olgu sunuldu.

Anahtar Kelimeler

Yenidoğan, tromboz

Kaynakça

• Schmidt B, Andrew M. Neonatal thrombosis report of a prospective Ca- nadian and international registry. Pediatrics 1995;96:939.
• Nowak-Göttl U, VonKries R, Göbel U. Neonatal symptomatic thrombo embolism in Germany: two year surwey. Arch Dis Child Fetal Neonatal Ed 1997; 76: 163.
• Zigman A, Yazbeck S, Emil S, Nyugen L. Renal vein thrombosis: A 10- year review. J Pediatr Surg 2000; 35:1540.
• Kosch A, Kuwertz-Bröking E, Heller C, et al. Renal venous thrombosis in neonates: prothrombotic risk factors and long-term follow-up. Blood 2004; 104:1356.
• Winyard PJ, Bharucha T, De Bruyn R, Dillon MJ, van’tHoff W, Trompeter RS. Perinatal renal venous thrombosis: presenting renallength predicts out come. Arch Dis Child Fetal Neonatal Ed 2006; 91:273.
• Lau KK, Stoffman JM, Williams S, McCusker P, Brandao L, Patel S, Chan AK. Neonatal renal vein thrombosis: review of the English –language lite- rature between 1992 and 2006. Pediatrics 2007; 120:1278.
• Edstrom CS, Christensen RD. Evaluation and treatment of thrombosis in the neonatalintensive careunit. Clin Perinatol 2000; 27:623.
• Andrew ME, Monagle P, deVeber G, Chan AK.Thromboembolic disease and antithrombotic therapy in newborns. Hematology Am Soc Hematol Educ program 2001; 358.
• Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen DM, Powers P.. Development of the human coagulation system in the full-ter- minfant. Blood 1987; 70:165.
• Andrew M, Paes B, Milner R, Johnston M, Mitchell L, Tollefsen DM, Cast- le V, Powers P. Development of the human coagulation system in the healthy premature infant. Blood 1988; 72:1651.
• Andrew M, Vegh P, Johnston M, Bowker J, Ofosu F, Mitchell L. Maturation of the hemostatic system during childhood. Blood 1992; 80:1998.
• Schwartz DS, Gettner PA, Konstantino MM, Bartley CL, Keller MS, Eh- renkranz RA, Jacobs HC.Umblical venous catheterization and the risk of portal vein thrombosis. J Pediatr 1997; 131:760.
• Monagle P, Chan AK, Goldenberg NA, Ichord RN, Journeycake JM, Nowak-Göttl U, Vesely SK. Anti thrombotic therapy in neonates and children: Antithrombotic therapy and prevention of thrombosis. Chest 2012;141:737–801.