PRIMARY MALIGN MELANOMA OF VAGİNA: CASE REPORT

Yıl 2012, Cilt: 9 Sayı: 35, 1464 - 1466, 01.07.2012

Müjdegül Karaca Cihan Toğrul Özlem Altınkaya Eralp Başer Ebru H Biberoğlu Levent Şirvan Tayfun Güngör

Öz

Malignant melanoma, a rare tumor of the skin and mucosal membranes has high invasion potential. Overall prognosis of mucosal melanoma is worse than cutaneus melanomas. A 67 year old woman with primary malignant vaginal melonoma who was treated surgically with wide local excision and postoperatif adjuvant chemotherapy with interferon 2α was presented. Although malignant melanoma of the female genital tract is uncommon,elderly patients should undergo regular gynecologic examinations. Suspicious pigmented lesions should biopsied; however, the prognosis is poor and these tumors are associated with high rate of recurrence and low long term survival. Surgery is the cornersto- ne of the treatment.

Anahtar Kelimeler

Malignant melanoma, vagina

VAJİNANIN PRİMER MALİGN MELANOMU:OLGU SUNUMU

Öz

Malign melanom yüksek malign potansiyeli olan deri ve mukozal membranları tutan bir nadir tümördür. Genel prognozu deri melanomlarından ve kutanöz melanomlardan daha kötüdür. 67 yaşında vajinal kanama ve vajende ele gelen kitle şikayetleriyle hastanemiz jinekolojik onkolojik cerrahi ünitesine başvuran hastanın, yapılan vajinal biyopsisinde primer vajinal malign melanom tespit edildi. Takiben geniş lokal eksizyon yapıldı. Postoperatif dönemde interlökin 2α ile adjuvan kemoterapi tedavisi yapıldı. Malign melanom, kadın genital sis- teminde nadir görülen bir tümör olmasına rağmen, ileri yaş hastalar rutin jinekolojik muayene esnasında dikkatli inspeksiyonla değerlendirilmeli, şüpheli pigmente lezyonlardan biyopsi yapılmalıdır. Bu tümörlerin prognozu oldukça kötüdür, uygulanan tedaviye rağmen yüksek düzeyde rekürrens saptanır ve uzun dönem sağkalım oranları düşüktür. Primer tedavi yöntemi cerrahidir.

Anahtar Kelimeler

malign melanom, vajina

Kaynakça

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