Yıl 2020,
Cilt: 17 Sayı: 1, 315 - 317, 31.03.2020
Demet Çam
,
Handan Bezirganoğlu
,
Fatma Sarı
,
Evrim Alyamac Dizdar
,
Şerife Oğuz
,
Cüneyt Tayman
Kaynakça
- Referans1. Shah PS. Hypothermia: a systematic review and meta-analysis of clinical trials. Semin Fetal Neonatal Med 2010; 15(5):238-246.
- Referans2. Tren TJ, Sheth AP. Complications of subcutaneous fat necro¬sis of newborn: a case report and review of literature. Pediatric Dermatol 2003; 20:257-261.
- Referans3. Akin MA, Akın L, Sarıcı D, Yılmaz İ, Balkanlı S, Kurtoğlu S. Follow-up during early infancy of newborns diagnosed with subcutaneous fat necrosis. J Clin Res. Pediatr Endocrinol 2011; 3:216-218.
- Referans4. Oza V, Treat J, Cook N, Tetzlaff MT, Yan A. Subcutaneous fat necrosis as a complication of whole body cooling for birth asphyxia. Arch Dermatol 2010; 146:882-885.
- Referans5. Mahe E, Girszyn N, Hadj-Rabia S, Bodemer C, Hamel-Teillac D, De Prost Y. Subcutaneous fat necrosis of the new¬born: a systematic evaluation of risk factors, clinical manifes¬tations, complications and outcome of 16 children. Br J Dermatol 2007; 156:709-715.
- Referans6. Mather MK, Sperling LC, Sau P. Subcutaneous fat necrosis of the newborn. lnt J Dermatol 1997; 36(6):450-452.
- Referans7. Varan B, Gürakan B, Ozbek N, Emir S. Subcutaneous fat necrosis of the newborn associated with anemia. Pediatr Dermatol 1999; 16(5):381-383.
- Referans8. Shumer DE, Thaker V, Taylor GA, Wassner AJ. Severe hypercalsemia due to subcutaneous fat necrosis: presentation, management and complications. Arch Dis Child Fetal Neonatal Ed 2014; 99(5):419-421.
- Referans9. Ergin H, Tan M, Küçüktaşcı K, Ergin Ş, Yalçın N, Özdemir ÖMA. Subcutaneous fat necrosis associated with perinatal asphyxia presenting hypo/hypercalcemia in a newborn. Çocuk Sağlığı ve Hastalıkları Dergisi 2013; 56:184-185.
- Referans10. Strohm B, Hobson A, Brocklehurst P et al. Subcutaneous fat necrosis after moderate therapeutic hypothermia in neonates. Pediatrics 2011; 128:e450–e452.
- Referans11. Katz DA, Huerter C, Bogard P et al. Subcutaneous fat necrosis of the newborn. Arch Dermatol 1984; 120:1517– 1518.
- Referans12. Burden AD, Krafchik BR. Subcutaneous fat necrosis of the newborn: a review of 11 cases. Pediatr Dermatol 1999; 16:384–387.
- Referans13. Mallory SB, Colven R. Disorders of subcutaneous tissue in the newborn. In: Harper J, Orange A, Prose N, eds. Textbook of Pediatric Dermatology. Vol. 1. 2nd ed. Oxford: Blackwell Publising; 2006; 66-71.
- Referans14. Borgia F, De Pasquale L, CacaceCet al. Subcutaneous fat necrosis of the newborn: be aware of hypercalcaemia. J Paediatr Child Health 2006; 42:316–318.
- Referans15. Farooque A, Moss C, Zehnder D et al. Expression of 25- hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis. Br J Dermatol 2009; 160:423–425.
Hipotermi Tedavisi Sonrası Subkutan Yağ Dokusu Nekrozu Gözlenen Bir Yenidoğan Olgusu
Yıl 2020,
Cilt: 17 Sayı: 1, 315 - 317, 31.03.2020
Demet Çam
,
Handan Bezirganoğlu
,
Fatma Sarı
,
Evrim Alyamac Dizdar
,
Şerife Oğuz
,
Cüneyt Tayman
Öz
Subkutan yağ dokusu nekrozu (SKYN), term infantlarda genellikle doğum asfiksisi sonrası hipotermi tedavisi sonrası görülen, adipoz dokunun inflamatuar bozukluğu olan nadir bir pannikülit şeklidir. Preterm bebeklerde de predispozan risk faktörleri (doğum asfiksi, gebelik diyabeti vb.) ile birlikte görülebilir. Hastalık, yaşamın ilk haftalarında gelişen, akut, benign, kendi kendini sınırlayan bir pannikülittir. Herhangi bir müdahale olmadan haftalar veya aylar içinde kendiliğinden düzelebilir, ancak potansiyel komplikasyonları da olabilir. Biz burada, hipotermi tedavisi sonrası yaşamının 8. gününde, sırtında ve omuzlarında generalize multiform eritematöz döküntü ve soluk plaklar ile subkutan yağ nekrozu gelişen ve komplikasyonsuz olarak normokalsemi ile takip edilen bir yenidoğan vakasını sunuyoruz. Hipotermi protokollerinin SKYN gelişimi için risk artışına neden olabilmektedir. Klinisyenler bu komplikasyonun farkında olmalı ve cilt remisyonundan sonra bile, hiperkalsemi riski nedeniyle dikkatli olmalıdır.
Kaynakça
- Referans1. Shah PS. Hypothermia: a systematic review and meta-analysis of clinical trials. Semin Fetal Neonatal Med 2010; 15(5):238-246.
- Referans2. Tren TJ, Sheth AP. Complications of subcutaneous fat necro¬sis of newborn: a case report and review of literature. Pediatric Dermatol 2003; 20:257-261.
- Referans3. Akin MA, Akın L, Sarıcı D, Yılmaz İ, Balkanlı S, Kurtoğlu S. Follow-up during early infancy of newborns diagnosed with subcutaneous fat necrosis. J Clin Res. Pediatr Endocrinol 2011; 3:216-218.
- Referans4. Oza V, Treat J, Cook N, Tetzlaff MT, Yan A. Subcutaneous fat necrosis as a complication of whole body cooling for birth asphyxia. Arch Dermatol 2010; 146:882-885.
- Referans5. Mahe E, Girszyn N, Hadj-Rabia S, Bodemer C, Hamel-Teillac D, De Prost Y. Subcutaneous fat necrosis of the new¬born: a systematic evaluation of risk factors, clinical manifes¬tations, complications and outcome of 16 children. Br J Dermatol 2007; 156:709-715.
- Referans6. Mather MK, Sperling LC, Sau P. Subcutaneous fat necrosis of the newborn. lnt J Dermatol 1997; 36(6):450-452.
- Referans7. Varan B, Gürakan B, Ozbek N, Emir S. Subcutaneous fat necrosis of the newborn associated with anemia. Pediatr Dermatol 1999; 16(5):381-383.
- Referans8. Shumer DE, Thaker V, Taylor GA, Wassner AJ. Severe hypercalsemia due to subcutaneous fat necrosis: presentation, management and complications. Arch Dis Child Fetal Neonatal Ed 2014; 99(5):419-421.
- Referans9. Ergin H, Tan M, Küçüktaşcı K, Ergin Ş, Yalçın N, Özdemir ÖMA. Subcutaneous fat necrosis associated with perinatal asphyxia presenting hypo/hypercalcemia in a newborn. Çocuk Sağlığı ve Hastalıkları Dergisi 2013; 56:184-185.
- Referans10. Strohm B, Hobson A, Brocklehurst P et al. Subcutaneous fat necrosis after moderate therapeutic hypothermia in neonates. Pediatrics 2011; 128:e450–e452.
- Referans11. Katz DA, Huerter C, Bogard P et al. Subcutaneous fat necrosis of the newborn. Arch Dermatol 1984; 120:1517– 1518.
- Referans12. Burden AD, Krafchik BR. Subcutaneous fat necrosis of the newborn: a review of 11 cases. Pediatr Dermatol 1999; 16:384–387.
- Referans13. Mallory SB, Colven R. Disorders of subcutaneous tissue in the newborn. In: Harper J, Orange A, Prose N, eds. Textbook of Pediatric Dermatology. Vol. 1. 2nd ed. Oxford: Blackwell Publising; 2006; 66-71.
- Referans14. Borgia F, De Pasquale L, CacaceCet al. Subcutaneous fat necrosis of the newborn: be aware of hypercalcaemia. J Paediatr Child Health 2006; 42:316–318.
- Referans15. Farooque A, Moss C, Zehnder D et al. Expression of 25- hydroxyvitamin D3-1alpha-hydroxylase in subcutaneous fat necrosis. Br J Dermatol 2009; 160:423–425.