Kolorektal Kanser ve D Vitamini

Öz

Kolorektal kanser dünyada üçüncü sırada yaygın görülen kanser türüdür. Kolorektal kanser risk faktörlerinden biri düşük D vitamini düzeyidir. D vitamini eksikliği dünyada artış gösteren bir sağlık sorunudur. D vitamini aktif formu kalsitriol olarak bilinen 1,25-Dihidroksikolekalsiferoldur. Bu form bazı biyolojik süreçler ve immün sistem düzenlenmesinde görev alır. D vitamini kolon, meme, prostat gibi pek çok kanser türü ile ilişkilidir. Tedavi sürecinde de önemli etkileri olan D vitaminin cerrahi müdahale veya kemoterapi tedavisi sonrası plazma seviyesinin yüksek olması daha iyi sağ kalım ile ilişkili bulunmuştur.

Anahtar Kelimeler

• Beslenme
• D vitamini
• D vitamini reseptörü
• Kanser
• Kolorektal kanser

Colorectal Cancer and Vitamin D

Öz

Colorectal cancer is the third most common type of cancer in world. One of the risk factors for colorectal cancer is low vitamin D level. Vitamin D deficiency is an increasing health problem in the world. The active form of vitamin D is 1,25-dihydroxy vitamin D, known as calcitriol. This form is involved in some biological processes and immune system regulation. Vitamin D is associated with many types of cancer such as colon, breast, prostate. The high levels of vitamin D, which has important effects in the treatment process, has been found to be associated with better survival after surgery or chemotherapy treatment.

Anahtar Kelimeler

• Nutrition
• Vitamin D
• Vitamin D receptor
• Cancer
• Colorectal cancer

Kaynakça

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