Evaluation of the relationship of hemogram parameters with prognosis in older adults with acute abdominal pathologies

Yıl 2022, , 385 - 392, 15.03.2022

Hatice Şeyma Akça , Abdullah Algın , Serdar Özdemir , Burcu Yılmaz , İbrahim Altunok

https://doi.org/10.32322/jhsm.1039607

Cited By: 3

Öz

Aim: We aimed to investigate the effects of hemogram parameters on the short-term mortality of older adults with acute abdominal pathologies. Secondly, it was aimed to investigate the effect of hemogram parameters on mortality in operated and non-operated patients.
Material and Method: This retrospective observational study was conducted in an emergency medicine clinic between June 1, 2019, and June 1, 2020. Data on patients over 65 years of age who presented to the emergency department with acute abdominal pathologies were analyzed. Hemogram parameters, as in our patient group over 65 years old, who presented with all acute abdomen pathologies; It was examined in terms of its relationship with prognosis in our operated and non-operated patient group. Statistical analysis was performed using SPSS v. 26.0.
Results: The study included a total of 744 patients, of whom 391(52.6%) were women. Mortality was seen in 114(15.32%) patients, and 83(11.2%) patients underwent surgery. AUC and cut off values are for leukocytes count 0.590 and 10.83 for neutrophils count 0.596 and 9.64 for neutrophil-lymphocyte ratio 0.606 and 8.24 to predict mortality (p=0.002, p=0.001, and p>0.001, respectively
Conclusion: In this study, among the hemogram parameters; leukocytes, neutrophils and neutrophil-lymphocyte ratio were determined to have a statistically significant ability to predict mortality in older adults both operaple and non operabl groups groups presenting with acute abdominal pathologies, but their accuracy rates were low.

Anahtar Kelimeler

leukocytes, neutrophils, lymphocytes, general surgery

Kaynakça

• Davis P, Hayden J, Springer J, Bailey J, Molinary M, Jhonson P. Prognostic factors for morbidity and mortality in elderly patients undergoing acute gastrointestinal surgery: a systematic review. Can J Surg 2014; 57: E44–E52.
• Kim K, Park K, Koo K, Han H, Kim C. Comprehensive geriatric assessment can predict postoperative morbidity and mortality in elderly patients undergoing elective surgery. Archives of Gerontology and Geriatrics 2013; 56: 507-12.
• Liu X-M, Ma C-S, Liu X-H, et al. Relationship between red blood cell distribution width and intermediate-term mortality in elderly patients after percutaneous coronary intervention. J Geriatr Cardiol 2015; 12: 17–22.
• Abdullah HR, Sim YE, Sim YT, et al. Preoperative red cell distribution width and 30-day mortality in older patients undergoing non-cardiac surgery: a retrospective cohort observational study. Sci Rep 2018; 8: 6226.
• Ichinose U, Murakawa T, Kawashima M, et al. Prognostic significance of red cell distribution width in elderly patients undergoing resection for non-small cell lung cancer. J Thorac Dis 2016; 8: 3658–66.
• Vaughan-Shaw PG, Rees JRE, King AT. Neutrophil lymphocyte ratio in outcome prediction after emergency abdominal surgery in the elderly. Int J Surg 2012; 10: 157-62.
• Verwijmeren L, Bosma M, Vernooij LM, et al. Associations between preoperative biomarkers and cardiac surgery–associated acute kidney injury in elderly patients: a cohort study. Anesth Analg 2021; 133: 570-7.
• Wu W, Schifftner TL, Henderson WG, et al. Preoperative hematocrit levels and postoperative outcomes in older patients undergoing noncardiac surgery. JAMA 2007; 297: 2481-8.
• Wei‐Hsiang H, Zhu Y, Zhang J, Zhang Y. Pretreatment red blood cell distribution width as an efficient predictor of survival in older patients undergoing hip fracture surgery. Int J Clin Pract 2021; 00: e14791.
• Sakai Y, Wakao N, Matsui H, Watanabe T, Lida H, Katsumi A. Elevated red blood cell distribution width is associated with poor outcome in osteoporotic vertebral fracture. J Bone Miner Metab 2021; 39: 1048-57.
• Cigsar G, Yıldırım AC, Anuk T, et al. Neutrophil to lymphocyte ratio on appendectomy of geriatric and nongeriatric patients. J Invest Surg 2017; 30: 285-90.
• Pantoja Pachajoa DA, Gielis M, Palacios Huatuco RM, et al. Annals of medicine and surgery neutrophil-to-lymphocyte ratio vs c-reactive protein as early predictors of anastomotic leakage after colorectal surgery: a retrospective cohort study. Ann Med Surg (Lond) 2021; 64: 102-201.
• Rosa F, Covino M, Cozza V, et al. Management of acute cholecystitis in elderly patients: A propensity score-matched analysis of surgical vs. medical treatment. Dig Liver Dis 2021; 53: 1620-6.
• Shepherd SJ, Creber N, Mansour K, Wiesenfeld D, Iseli TA, Amott D. Relationship between age, comorbidities and complications in head and neck cancer patients undergoing curative surgery. ANZ J Surg 2020; 90: 851-5.
• Rao C, Sun Myint A, Athanasiou T, et al. Avoiding radical surgery in elderly patients with rectal cancer is cost-effective. Dis Colon Rectum 2017; 60: 30-42.