Relationship between glycosylated hemoglobin and plateletcrit of type 2 diabetes patients

Abstract

Aim: Type 2 diabetes can cause serious vascular problems. Abnormal plateletcrit (PCT) levels were shown as a risc factor for coronary artery diseases by recent studies. Glycosylated hemoglonin (HbA1c) is widely ysed marker for assessment of glycemic control. This study aimed to evaluate relationship between HbA1c and PCT.

Material and Method: It is retrospective case control study. 65 type 2 diabetic patients’ records were evaluated. Correlation between HbA1c and PCT, MPV was investigated.

Results: Between HbA1c and PCT levels, statistically significant correlation was detected (r=0,4 p<0,01). Any correlation wasn’t detected with MPV.

Conclusion: Plateletcrit may be guide for preventing vascular complication due to poor glycemic regulation. Therefore patients with increased plateletcrit values, should be evaluated for higher risk of vascular complications.

Keywords

• HbA1c,glycemic control,plataletcrit,type 2 diabetes

Tip 2 diyabet hastalarında glikolize hemoglobin ve plataletcrit ilişkisi

Abstract

Amaç: Tip 2 diyabet ciddi damar hastalıklarına yol açabilen bir hastalıktır. Plateletcrit (PCT) anormal düzeyleri yapılan çalışmalarda koroner arter hastalıkları için risk faktörü olarak belirlenmiştir. Glikolize hemoglobin (HbA1c), glisemik kontrolü değerlendirmek için geniş kullanıma sahip bir belirteçtir. Bu çalışmada PCT ile HbA1c arasındaki ilişkinin değerlendirilmesi amaçlanmıştır.

Gereç ve yöntem: Çalışma, retrospektif vaka kontrol çalışmasıdır. Tip 2 diyabetli 65 hastanın geçmiş kayıtları değerlendirilmiş,HbA1c ve MPV, PCT arasındaki ilişki araştırılmıştır.

Bulgular: HbA1c ve PCT arasında anlamlı korelasyon saptandı (r=0,4 p<0,01). MPV ile korelasyon saptanmadı.

Sonuç: PCT, glisemik kontrolü sağlanmayan ve buna bağlı vasküler hasar gelişme olasılığı olan hastalarda yol gösterici olabilir. Bu açıdan, anormal PCT düzeyleri olan hastaların vasküler patolojiler açısından yakın takibi önemli olabilir.

Keywords

• HbA1c,plataletcrit,glisemik kontrol,tip 2 diyabet

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