Pulmonary involvement in connective tissue disease due to Coronavirus 19: a case report

Year 2021, Volume: 4 Issue: 3, 394 - 396, 21.05.2021

Ömer Faruk Topaloğlu , Halil Özer , Abidin Kılınçer , Emine Uysal

https://doi.org/10.32322/jhsm.887656

Abstract

Coronavirus disease (COVID-19) is a disease caused by the new coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerging in Wuhan, China's Hubei province. The epidemic spread exponentially across the world and became a pandemic [1-3]. Fever, dry cough, headache, and shortness of breath all typical symptoms, and can lead to death with acute respiratory distress syndrome. Diabetes mellitus, hypertension, coronary heart disease, chronic obstructive pulmonary disease and chronic kidney disease tend to be major risk factors for mortality [4]. Real-time fluorescence reverse transcription- polymerase chain reaction (RT-PCR) is the preferred initial and reference diagnostic test for COVID-19. Chest computed tomography (CT) has gained importance due to the long result time and false negativity of the RT-PCR test [5, 6]. Typical imaging findings for COVID-19 pneumonia are peripheral, bilateral, ground glass opacities with or without consolidation, and the differential diagnosis comprises influenza pneumonia, organizing pneumonia, drug toxicity, and connective tissue disease [7].
Due to immune dysfunction, steroid usage and immunotherapy, connective tissue diseases are vulnerable to viral infections. Few studies have identified the presence of concurrent COVID-19 in patients with connective tissue diseases [8, 9]. In this article, we aimed to present the chest CT findings of a patient with connective tissue diseases who received immunosuppressed therapy

Keywords

COVID-19, Connective tissue disease, Sjogren’s syndrome, ground glass opacity

References

• Liu P, Tan XZ. 2019 Novel Coronavirus (2019-nCoV) Pneumonia. Radiology 2020; 295: 19.
• Zhu N, Zhang D, Wang W, et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. N Engl J Med 2020; 382: 727-33. doi:10.1056/NEJMoa2001017.
• Sun Z. Diagnostic Value of Chest CT in Coronavirus Disease 2019 (COVID-19). Current medical imaging 2020; 16: 274-5.
• Ouédraogo D-D, Tiendrébéogo WJS, Kaboré F, Ntsiba H. COVID-19, chronic inflammatory rheumatic disease and anti-rheumatic treatments. Clinical Rheumatology 2020: 1.
• Li M, Lei P, Zeng B, et al. Coronavirus disease (COVID-19): spectrum of CT findings and temporal progression of the disease. Acad Radiol 2020.
• Li Y, Xia L. Coronavirus disease 2019 (COVID-19): role of chest CT in diagnosis and management. Am J Roentgenol 2020; 214: 1280-6.
• Simpson S, Kay FU, Abbara S, et al. Radiological Society of North America Expert Consensus Statement on Reporting Chest CT Findings Related to COVID-19. Endorsed by the Society of Thoracic Radiology, the American College of Radiology, and RSNA. Radiology: Cardiothoracic Imaging 2020; 2: e200152.
• Cheng C, Li C, Zhao T, et al. COVID-19 with rheumatic diseases: a report of 5 cases. Clinical rheumatology 2020: 1-5.
• Santos CS, Morales CM, Álvarez ED, Castro CÁ, Robles AL, Sandoval TP. Determinants of COVID-19 disease severity in patients with underlying rheumatic disease. Clin Rheumatol 2020; 39: 2789-96.
• Kanne JP. Chest CT Findings in 2019 Novel Coronavirus (2019-nCoV) Infections from Wuhan, China: Key Points for the Radiologist. Radiology 2020;295: 16-7.
• Pan Y, Guan H, Zhou S, et al. Initial CT findings and temporal changes in patients with the novel coronavirus pneumonia (2019-nCoV): a study of 63 patients in Wuhan, China. Eur Radiol 2020: 1-4.
• Bernheim A, Mei X, Huang M, et al. Chest CT findings in coronavirus disease-19 (COVID-19): relationship to duration of infection. Radiology 2020: 200463.
• Gianfrancesco M, Hyrich KL, Al-Adely S, et al. Characteristics associated with hospitalisation for COVID-19 in people with rheumatic disease: data from the COVID-19 Global Rheumatology Alliance physician-reported registry. Ann Rheum Dis 2020.
• Ye C, Cai S, Shen G, et al. Clinical features of rheumatic patients infected with COVID-19 in Wuhan, China. Ann Rheum Dis 2020.
• Larici AR, Cicchetti G, Marano R, et al. Multimodality imaging of COVID-19 pneumonia: from diagnosis to follow-up. A comprehensive review. Eur J Radiol 2020: 109217.