Review of COVID-19 vaccinated patients' emergency room admissions

Yıl 2022, Cilt: 5 Sayı: 1, 18 - 21, 17.01.2022

Ensar Durmuş , Necip Gökhan Guner , Fatih Güneysu , Nuray Aslan , Yusuf Yurumez

https://doi.org/10.32322/jhsm.969409

Cited By: 1

Öz

Introduction: This study was aimed to define the demographic structure of vaccinated patients admitted to the emergency room (ER) with COVID-19 symptoms, and their hospitalization status, length of stay (LoS) in hospital, and mortality status.
Material and Method: This research is a retrospective, cross-sectional and descriptive study. Furthermore, it includes the period between 15.01.2021 and 30.04.2021.
Results: An 887 COVID-19 vaccinated patients who applied to ER. Of these, 383 (42.2%) were male, and 504 (56.8%) were female. The mean age of the patients was 52±18.6 years. The number of single-dose vaccinated patients was 696 (78.5%), and the two-dose vaccinated was 191 (21.5%). CoronaVac (Sinovac Life Sciences) vaccine was applied to 755 (85.1%), and BNT162b2 (Pfizer & Biontech) vaccine was applied to 132 (14.9%) patients before.
In 317 (35.7%) cases, reverse transcription-polymerase chain reaction (Rt-PCR) positivity was detected in the ER application after vaccination. Of the total patients, 86 (9.7%) were hospitalized, 14 (1.4%) patients died in the hospital.
The mean time between vaccination and application to ER was 25 (±21.9) days. Also, this period was 28.1 (±18) days in two-dose vaccinated patients.
Conclusion: People who are vaccinated with the COVID-19 vaccine continue to have hospital admissions with COVID-19 symptoms. Rt-PCR positivity, need for hospitalization, and mortality may continue to be seen in vaccinated individuals.

Anahtar Kelimeler

pandemic, Covid-19, vaccine, emergency room

Kaynakça

• WHO announces COVID-19 outbreak a pandemic [Internet]. World Health Organization; 2020 [cited 2020 Apr 11]. Available from:http://www.euro.who.int/en/health-topics/health-emergencies/coronavirus-COVID-19/news/news/2020/3/who-announces-COVID-19-outbreak-a-pandemic
• Durmuş E, Güneysu F. Effect of COVID-19 on the admissions to the adult emergency department. J Contemp Clin Pract 2020; 6: 58–63.
• Trivedi N, Verma A, Kumar D. Possible treatment and strategies for COVID-19: review and assessment. Eur Rev Med Pharmacol Sci 2020; 24: 12593–608.
• Bhavana V, Thakor P, Singh SB, Mehra NK. COVID-19: Pathophysiology, treatment options, nanotechnology approaches, and research agenda to combating the SARS-CoV2 pandemic. Life Sci 2020; 261: 118336.
• Zhao J, Zhao S, Ou J, et al. COVID-19: Coronavirus vaccine development updates. Front Immunol 2020; 11: 602256.
• Pan D, Mudalige NL, Sze S, et al. The new UK SARS-CoV-2 variant and lockdown-causes and consequences. Clin Med Lond Engl 2021; 21: e295.
• Naqvi AAT, Fatima K, Mohammad T, et al. Insights into SARS-CoV-2 genome, structure, evolution, pathogenesis and therapies: Structural genomics approach. Biochim Biophys Acta BBA-Mol Basis Dis. 2020; 1866: 165878.
• Hodgson SH, Mansatta K, Mallett G, Harris V, Emary KRW, Pollard AJ. What defines an efficacious COVID-19 vaccine? A review of the challenges assessing the clinical efficacy of vaccines against SARS-CoV-2. Lancet Infect Dis 2021; 21: e26–35.
• [T.R. Ministry of Health COVID-19 Vaccine Information Platform] T.C. Sağlık Bakanlığı COVID-19 Aşısı Bilgilendirme Platformu [İnternet]. Turkey Vaccine Table. 2021 [cited 2021 Apr 30]. Available from: https://COVID19asi.saglik.gov.tr/
• Coronavirus (COVID-19) Vaccinations-Statistics and Research [Internet]. Our World in Data. 2021 [cited 2021 Apr 30]. Available from: https://ourworldindata.org/COVID-vaccinations
• [COVID-19 Vaccine National Implementation Strategy] COVID-19 Aşısı Ulusal Uygulama Stratejisi [İnternet]. [T.R. Ministry of Health COVID-19 Vaccine Information Platform]T.C. Sağlık Bakanlığı COVID-19 Aşısı Bilgilendirme Platformu. 2021 [cited 2021 Apr 30]. Available from: https://COVID19asi.saglik.gov.tr/TR-77706/COVID-19-asisi-ulusal-uygulama-stratejisi.html
• [COVID-19 (Sars-Cov-2 Infection) General Information, Epidemiology And Diagnosis] COVID-19 (Sars-Cov-2 Enfeksiyonu ) Genel Bilgiler, Epidemiyoloji ve Tanı [İnternet]. T.C. Sağlık Bakanlığı; 2020 [cited 2021 Apr 30]. Available from: https://COVID19.saglik.gov.tr/Eklenti/39551/0/COVID-19rehberigenelbilgilerepidemiyolojivetanipdf.pdf
• George D, Mallery P. IBM SPSS statistics 25 step by step: a simple guide and reference. Fifteenth edition. New York ; London: Routledge, Taylor & Francis Group; 2019. 404 p.
• Guneysu F, Guner NG, Erdem AF, Durmus E, Durgun Y, Yurumez Y. Can COVID-19 mortality be predicted in the emergency room? J Coll Physicians Surg Pak 2020; 31: 928–32.
• Hospitalization Demographics | NC DHHS COVID-19 [Internet]. 2021 [cited 2021 May 1]. Available from: https://COVID19.ncdhhs.gov/dashboard/hospitalization-demographics
• Richardson S, Hirsch JS, Narasimhan M, et al. Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the New York City area. JAMA 2020; 323: 2052.