Aim: Factor analysis is a statistical approach used mainly in social science scale development systems. The aim of this study was to evaluate the performance of factorial structures formed by laboratory values in predicting mortality in severe COVID-19 patients.
Material and Method: The study included 281 patients diagnosed with ‘‘severe coronavirus infection’’ according to the WHO COVID-19 clinical management guideline who were treated in a 13-bed adult tertiary-level critical care unit of a tertiary level hospital. For a total of 23 variables (ALT, AST, BUN, creatinine, Na, K, LDH, CRP, CK, ferritin, D-dimer, INR, TB, Glu, NLR, WBC, fibrinogen, % NEU, PLT, HTC, % LYM, TLC, Alb), laboratory values were collected. A two-step method was used to determine if exploratory factors might be used in place of laboratory variables. First, the ability of individual laboratory variables to predict mortality was obtained by analysis of the receiver operating characteristic (ROC) analysis. Then, the ability of factors created from these variables to predict mortality was measured using ROC analysis. The area under curve (AUC) values were compared between the two conditions.
Results: The Kaiser-Meyer-Olkin (KMO) value calculated using factor analysis on the variables was found to be 0.661. The significance level of the Bartlett’s Test was <0.001. The correlation matrix determinant was found to be 0.001. CRP, ferritin, LDH, D-dimer, PLT, and TLC all had AUC values >0.6. A five-factor structure was created based on the Scree Plot. The fifth factor, which included CRP, fibrinogen, and ferritin, was the highest for predicting mortality (AUC: 0.677). According to the individual laboratory variables, the first factor comprising TLC, CK, and NLR, had the most remarkable success (AUC: 0,642).
Conclusions: The factor analysis approach can be used to present an alternative perspective for predicting mortality in COVID-19 critical disease. The factor including CRP, fibrinogen, and ferritin predicted mortality at the highest rate in this study.
Covid-19 factor analysis critically ill mortality Coronavirus disease 2019
Birincil Dil | İngilizce |
---|---|
Konular | Sağlık Kurumları Yönetimi |
Bölüm | Orijinal Makale |
Yazarlar | |
Yayımlanma Tarihi | 15 Mart 2022 |
Yayımlandığı Sayı | Yıl 2022 Cilt: 5 Sayı: 2 |
Üniversitelerarası Kurul (ÜAK) Eşdeğerliği: Ulakbim TR Dizin'de olan dergilerde yayımlanan makale [10 PUAN] ve 1a, b, c hariç uluslararası indekslerde (1d) olan dergilerde yayımlanan makale [5 PUAN]
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Not: Dergimiz WOS indeksli değildir ve bu nedenle Q olarak sınıflandırılmamıştır.
Yüksek Öğretim Kurumu (YÖK) kriterlerine göre yağmacı/şüpheli dergiler hakkındaki kararları ile yazar aydınlatma metni ve dergi ücretlendirme politikasını tarayıcınızdan indirebilirsiniz. https://dergipark.org.tr/tr/journal/2316/file/4905/show
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