Choroidal thickness and retinal nerve fiber layer analysis in chronic spontaneous urticaria

Yıl 2022, Cilt: 5 Sayı: 6, 1650 - 1653, 25.10.2022

Kürşad Ramazan Zor , Gamze Yıldırım Biçer Hatice Yıldız

https://doi.org/10.32322/jhsm.1176438

Öz

Aim: In this study, we investigated the effects of chronic spontaneous urticaria on the choroid and retinal nerve fiber layer.
Material and Method: The patient group consisted of newly diagnosed 54 chronic spontaneous urticaria (CSU ) patient and the control group consisted of 54 healthy volunteer. Choroidal and retinal nerve fiber layer (RNFL) thickness measurements were performed with Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA, USA) 30 minutes after pupil dilation with 0,5% tropicamide.
Results: In the patient group, nasal choroidal thickness (NCT) was 290.11±43.16 μm, subfoveal choroidal thickness (SFCT) was 339.17±37.709 μm, temporal choroidal thickness (TCT) was 296.00±42.859 μm, mean choroidal thickness (MCT) was 308.33±35.923 μm and RNFL thickness was 91.11±7.393 μm. NCT was 248.42±35,742 μm, SFCT 276.56±40.04 μm, TCT 253.69±37.384 μm, MCT 259.50±32,986 μm and RNFL thickness 92.19±8.719 μm in the control group. When we examine the p value, it is seen that both groups are similar to each other in terms of RNFL thickness (p=0.326), while there is a significant thickening in all choroidal regions of patients with CSU, including NCT, SFCT, TCT, MCT (p=0.000, p=0.000, p=0.000, p=0.000, respectively).
Conclusion: The choroid is affected in CSU and choroidal thickness can be a noninvasive method that can be used in diagnosis CSU. However, studies of longer disease durations may provide more illuminating information about CSU and choroid and RNFL.

Anahtar Kelimeler

Choroidal thickness, chronic spontaneous urticaria, EDI-OCT, histamine, retinal nerve fiber layer

Kaynakça

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