Characteristics of pediatric patients with chronic cough: data from a pediatric immunology and allergy outpatient clinic

Yıl 2025, Cilt: 8 Sayı: 1, 75 - 79, 12.01.2025

Hilal Ünsal , Beyza Ertürk

https://doi.org/10.32322/jhsm.1567695

Öz

Aims: Chronic cough is a common complaint in childhood. A differential diagnosis is very important in children with a chronic cough. We aimed to investigate the etiology and underlying risk factors of chronic cough in children.
Methods: Patients aged 1-18 years who were referred to Sincan Training and Research Hospital Pediatric Immunology and Allergy Outpatient Clinic were included. Demographic, clinical and laboratory features of patients were recorded.
Results: The study included 403 children with a median age of 8 years (IQR 6-12) (53% males). 30% of patients had allergic rhinitis (AR), 4.7% of patients had atopic dermatitis (AD), and 2% patients had food allergy (FA) history. 78(19.3%) patients also complained of dyspnea and 9 (2.2%) patients had a diagnosis of cardiovascular disease. 245 (60.8%) asthma-wheezy infant, 107 (26.6%) post-infectious cough, 36 (9%) postnasal drip syndrome, 9 (2.2%) gastroesophageal reflux and 6 (1.5%) psychogenic cough were detected in the whole group. The number of patients with accompanying dyspnea 76 (28.5%) and familial history of atopy 113 (42.3%) were higher in the asthma-wheezy infant group than others group (p<0.001 vs. p<0.001). Skin prick tests were performed in 273 patients and the presence of aeroallergen sensitivity was shown in 122 (30.2%) patients. Immunoglobulin deficiency was detected in 43 (10.7%) patients. Serum IgG, IgA, and IgM levels were low in 26 (6.5%), 18 (4.4%), and 12 (3%) patients, respectively.
Conclusion: We found the most common reasons are asthma and post-infectious cough in patients. Chronic cough can be the first symptom of primary immunodeficiency diseases and systemic diseases. A detailed history is necessary to avoid unnecessary procedures, treatments and to avoid delay in diagnosis.

Anahtar Kelimeler

Asthma, chronic cough, children, immunoglobulin

Etik Beyan

The study was conducted in accordance with the principles of the Declaration of Helsinki. Ethics committee approval was obtained for this retrospective study (Decision number: 2024-BÇEK/150)

Kronik öksürüğü olan pediatrik hastaların özellikleri: pediatrik immünoloji ve alerji polikliniğinden alınan veriler

Öz

Amaç: Kronik öksürük çocukluk çağında sık görülen bir şikayettir. Kronik öksürüğü olan çocuklarda ayırıcı tanı çok önemlidir. Çocuklarda kronik öksürüğün etiyolojisini ve altta yatan risk faktörlerini araştırmayı amaçladık.
Yöntemler: Sincan Eğitim ve Araştırma Hastanesi Çocuk İmmünoloji ve Alerji Polikliniğine sevk edilen 1-18 yaş arası hastalar çalışmaya dahil edildi. Hastaların demografik, klinik ve laboratuvar özellikleri kaydedildi.
Sonuçlar: Çalışmaya ortanca yaşı 8 yıl (IQR 6-12) olan 403 çocuk dahil edildi (%53 erkek). Hastaların %30'unda alerjik rinit (AR), %4,7'sinde atopik dermatit (AD) ve %2'sinde gıda alerjisi (FA) öyküsü vardı. 78 (%19,3) hastada ayrıca dispne şikayeti vardı ve 9 (%2,2) hastada kardiyovasküler hastalık tanısı vardı. Tüm grupta 245 (%60,8) astım-hırıltılı bebek, 107 (%26,6) postenfeksiyöz öksürük, 36 (%9) postnazal damla sendromu, 9 (%2,2) gastroözofageal reflü ve 6 (%1,5) psikojenik öksürük tespit edildi. Eşlik eden dispnesi olan hasta sayısı 76 (%28,5) ve ailede atopi öyküsü olan hasta sayısı 113 (%42,3) astım-hırıltılı bebek grubunda diğer gruplardan daha fazlaydı (p<0,001 vs. p<0,001). 273 hastaya deri prick testi yapıldı ve 122 (%30,2) hastada aeroalerjen duyarlılığı varlığı gösterildi. 43 (%10,7) hastada immünglobulin eksikliği tespit edildi. Serum IgG, IgA ve IgM düzeyleri sırasıyla 26 (%6,5), 18 (%4,4) ve 12 (%3) hastada düşüktü.
Sonuç: Hastalarda en sık görülen nedenlerin astım ve enfeksiyon sonrası öksürük olduğunu bulduk. Kronik öksürük, primer immün yetmezlik hastalıkları ve sistemik hastalıkların ilk belirtisi olabilir. Gereksiz prosedürlerden, tedavilerden kaçınmak ve tanıda gecikmeyi önlemek için ayrıntılı bir öykü gereklidir.

Anahtar Kelimeler

Astım, kronik öksürük, çocuklar, immünoglobulin

Kaynakça

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