Antibiotic susceptibilities of bacteria isolated from chronic suppurative otitis media

Öz

Background: To identify the bacteria that cause chronic suppurative otitis media and determine their antibiotic susceptibilities.

Material and Methods: We examined bacterial cultures that were isolated from the ear discharge of 180 patients who were admitted to the otolaryngology clinic between September 2014 and October 2015 due to suppurative bluish-green discharge from the middle ear. We also assessed the antibiotic susceptibilities of these microorganisms by retrospectively using the results of particular tests. The identification and antibiograms of bacteria were carried out using the VITEK 2 automated system.

Results: Microbial growth was detected in 162 of 180 samples (90%). The most frequently isolated strains were P. aeruginosa in 58 samples (35.8%) and S. aureus in 34 samples (20.9%). P. aeruginosa strains showed the highest sensitivity to amikacin (3.4%) and gentamicin (3.4%), but showed the greatest resistance to cefuroxime (82.7%) and trimethoprim/sulfamethoxazole (89.6%). S. aureus showed the lowest resistance to vancomycin (%0) and highest resistance to penicillin (88.2%) respectively.

Conclusion: We detected low resistance to aminoglycosides and quinolones, which are frequently used in the treatment of chronic suppurative otitis media. The detection of microorganisms, and a prior knowledge of their antibiotic susceptibilities, will contribute to successfully treating this disease.

Anahtar Kelimeler

• Otitis media,Pseudomonas aeruginosa,Staphylococcus aureus

Kaynakça

1. Celik O. Otolaryngology and Head and Neck Surgery. Turgut publishing, İstanbul 2002.p.160- 192.
2. Goycoolec MV, HvebMM, Ruchc. Otitis media, the pathogenesis approach. Otolaryngol clin North Am 1991; 24: 757- 761.
3. Fishman AJ, Marrinan MS, Huang TC, Kanowitz SJ. Total tympanic membrane reconstruction: AlloDerm versus temporalis fascia. Otolaryngol Head Neck Surg 2005; 132: 906-915.
4. Mayerhoff WL. Pathology of chronic suppurative otitis media. Ann Otol Rhinol Laryngol 1988; 97: 21-24.
5. Neely JG. Complications of temporal bone infections. In: Cummings CW, Fredrickson J, Harker LA, Krause CJ, Shüller DE, ed. Otolaryngology-Head and Neck Surgery. 2nd ed. St Louis: Mosby Year Book, 1993. p.2840-2864.
6. Amadasun JEO Bacteriology of inadequately treated active chronic otitis media in paediatric age group. The Journal of Laryngology and Otology. 1991;105: 341-342.
7. Indudharan R, Haq JA, Aiyar S. Antibiotics in chronic suppurative otitis media: a bacteriologic study. Ann Otol Rhinol Laryngol 1999; 108: 440-445.
8. Ozbakkaloglu B, Surucuoglu S, Unlu H, Kurutepe S, Ozkutuk N,Degerli K. Aerobik bacteria isolated from external auditory canal in chronic suppurative otitis media cases and their in-vitro susceptibility to antimicrobials. Journal of ANKEM 1998; 12: 457-462.

9. Gorur K, Ozcan C, Unal M, Ozturk C, Delialioglu N. Bacteria isolated in chronic suppurative otitis media and antibiotic suscebility. Mersin University School of Medicine Journal 2000; 1: 48-51.
10. Gul C, Kurnaz A, Turhan V, Oncul O, Pahsa A. Microorganisms isolated from middle ear cultures and their antibacterial susceptibility in patients with chronic suppurative otitis media. The Turkish Journal of Ear Nose and Throat 2006; 16: 164-168.
11. Sharma V, Kaur G. Microbiology and Antimicrobial Susceptibility Pattern of Cases of Chronic Suppurative Otitis Media in a Tertiary Care Teaching Hospital Int. J Bioassays 2014; 3: 3033-3035.
12. Kumar KGR, Navya S, Basavarajappa KG. A Study of Bacterial Profile and Antibiotic Susceptibility Pattern of Chronic Suppurative Otitis Media among Patients attending a Tertiary Care Centre, Davangere KG Sch. J App Med Sci 2014; 2: 1606-1612.
13. Lasisi OA, Nwaorgu OG. Behavioural pattern of malignant otitis external: 10-year review in Ibadan. Afr J Med Med Sci 2001; 30: 221-223.
14. Rubin Grandis J, Branstetter BF 4th, Yu VL. The changing face of malignant (necrotising) external otitis: clinical, radiological, and anatomic correlations. Lancet Infect Dis 2004; 4: 34-39.
15. Sundstrom J, Jacobson K, Munck-Wikland E, Ringertz S. Pseudomonas aeruginosa in otitis externa. A particular variety of the bacteria? Arch Otolaryngol Head Neck Surg 1996; 122: 833-836.
16. Sanlı A, Ozturk R, Paksoy M. Determıne The Spectrum of Mciroorganisms Encountered in Outpatients with Active-Stage Chronıc Supurative Otitis Media. J Kartal TR 2001; 12: 11-14.
17. Malkappa KS, Kondapaneni S, Surpam RB, Chakraverti TK. Study of Aerobic Bacterial Isolates and Their Antibiotic Susceptibility Pattern In Chronic Suppurative Otit Media Indian Journal of Otology 2012; 18: 136-113.