Early Therapeutic Penetrating Keratoplasty for Fungal Keratitis

Yıl 2016, Cilt: 1 Sayı: 1, 18 - 21, 30.06.2016

Yusuf Kocluk

Öz

Background: To
present two cases who developed fungal keratitis after an organic trauma and
who were treated with therapeutic penetrating keratoplasty in the early period.

Case
presentations: A 14
years old female and a 63 years old male patients came with the complaints of
pain after organic trauma. Fungal keratitis was diagnosed in both two cases.
TPKP was performed on the 5^th day of the topical antifungal
treatment (Case 1), on the 5^th day of the topical antifungal
treatment (Case 2)  and 7^th
day of the trauma (both two cases). Graft transparency was protected in the
post-operative period; no recurrence or fungal reactivation was detected in two
patients.

Conclusion: The study has proven that TPKP performed in the early period
of fungal keratitis enables rapid infection eradication and rapid visual
success.

Anahtar Kelimeler

Fungal keratitis, Early Therapeutic Penetrating Keratoplasty, Organic trauma

Kaynakça

• Ho JW, Fernandez MM, Rebong RA, Carlson AN, Kim T, Afshari NA Microbiological profiles of fungal keratitis: a 10-year study at a tertiary referral center. J Ophthalmic Inflamm Infect 2016; 6: 5.
• Klotz SA, Penn CC, Negvesky GJ, Butrus SI. Fungal and parasitic infections of the eye. Clin Microbiol Rev 2000; 13: 662-685.
• Xie L, Zhai H, Shi W. Penetrating keratoplasty for corneal perforations in fungal keratitis. Cornea 2007; 26: 158-162.
• Rautaraya B, Sharma S, Kar S, Das S, Sahu SK. Diagnosis and treatment outcome of mycotic keratitis at a tertiary eye care center in eastern India. BMC Ophthalmol 2011; 11: 39.
• Oechsler RA, Yamanaka TM, Bispo PJ, Sartori J, Yu MC, Melo AS, Miller D, Hofling-Lima AL. Fusarium keratitis in Brazil: genotyping, in vitro susceptibilities, and clinical outcomes. Clin Ophthalmol 2013; 7: 1693-1701.
• Rafael A Oechsler, Michael R Feilmeier, Darlene Mille. Fusarium keratitis: genotyping, in vitro susceptibility and clinical outcome. Cornea 2013; 32: 667–673.
• Perry HD, Doshi SJ, Donnenfeld ED, Bai GS. Topical cyclosporine A in the treatment of therapeutic keratoplasty for mycotic keratitis. Cornea 2002; 21: 161-163.
• Sharma N, Jain M, Sehra SV, Maharana P, Agarwal T, Satpathy G, Vajpayee RG. Outcomes of therapeutic penetrating keratoplasty from a tertiary eye care centre in northern India. Cornea 2014; 33(2): 114-118.
• Garq P, Roy A, Rof S. Update on fungal keratitis. Curr Opin Ophthalmol 2016; 27: 0-0(epub).