Araştırma Makalesi
BibTex RIS Kaynak Göster
Yıl 2020, Cilt: 5 Sayı: 2, 63 - 72, 30.06.2020

Öz

Kaynakça

  • 1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395:497–506 [Erratum in Lancet 2020; 395:496].
  • 2. Ajlan AM, Ahyad RA, Jamjoom LG, Alharthy A, Madani TA. Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings. AJR 2014; 203:782–787
  • 3. WHO. Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected: interim guidance. Jan 28, 2020.
  • 4. Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS. J Virol 2020 Jan 29 [Epub ahead of print]]
  • 5. Harmer D, Gilbert M, Borman R, Clark KL. Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme. FEBS Lett 2002; 532:107–110
  • 6. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395:507–513
  • 7. Koo HJ, Lim S, Choe J, Choi SH, Sung H, Do KH. Radiographic and CT features of viral pneumonia. RadioGraphics 2018; 38:719–739

Common clinical manifestations and the Thorax CT features of Coronavirus Disease 2019 (Covid-19) by stages

Yıl 2020, Cilt: 5 Sayı: 2, 63 - 72, 30.06.2020

Öz

Backround: The aim of this study is to report the clinical course of the disease and the correlation of thorax computed tomography (CT) feaures in patients with clinically suspected and laboratory confirmed COVID-19 pneumonia by reviewing the limited datas of literatüre.
Materials and Methods: Totally 104 patients (39 females and 65 males; age range, 22-91 years) admitted to our hospital with suspicion of COVID-19 pneumonia were retrospectively reviewed for common thorax CT features, laboratory findings and clinical manifestations.. All patients were positive in reverse transcriptase polymerase chain reaction test (RT-PCR) indicating Covid 19 pnemonia and all had abnormal CT findings. The main clinical signs, common laboratory findings and expressing the stages of the disease by CT findings were examined.
Results: 18 (17.3%) of the 104 patients with Covid 19 were as single, the remaining 86 (82.7%) were as multiple lesions on initial CT scans. The spread of these lesions were predominantly peripheral in 80 patients (76.9%) and peripheral-central in 24 patients (23.1%). In the early stage of the disease,lesions identified as ground glass opacites (GGO) whereas in the advanced stages, GGO and reticular pattern, air bubbles, subpleural fibrotic bands, air bronchograms, traction bronchiectasis and pleural effusion were observed. 52 patients who underwent routine blood tests, all (%100) had elevated C reactive protein (CRP) counts. 11patients (21.1%) had decreased leukocyte count. 48 patients (92.3%) had decreased lymphocyte count. 14 patients (28%) had increased d-dimer levels.
Conclusions: Various lesions were detected in the CT examine like parenchyma and/or interstitium involvement of patients with Covid 19 pneumonia. In early stages, parenchymal involvement were more frequent identified as a single or multiple GGO. Multilobar involvement, consolidation areas with air bubbles and bronchograms, widespread GGO and reticular pattern which is called crazy pavings were much more detected in the late stage of the disease. Prominent decrease in the lymphocyte count,and higher C-reactive protein levels were the most frequent laboratory findings.

Kaynakça

  • 1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395:497–506 [Erratum in Lancet 2020; 395:496].
  • 2. Ajlan AM, Ahyad RA, Jamjoom LG, Alharthy A, Madani TA. Middle East respiratory syndrome coronavirus (MERS-CoV) infection: chest CT findings. AJR 2014; 203:782–787
  • 3. WHO. Clinical management of severe acute respiratory infection when novel coronavirus (2019-nCoV) infection is suspected: interim guidance. Jan 28, 2020.
  • 4. Wan Y, Shang J, Graham R, Baric RS, Li F. Receptor recognition by novel coronavirus from Wuhan: an analysis based on decade-long structural studies of SARS. J Virol 2020 Jan 29 [Epub ahead of print]]
  • 5. Harmer D, Gilbert M, Borman R, Clark KL. Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme. FEBS Lett 2002; 532:107–110
  • 6. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395:507–513
  • 7. Koo HJ, Lim S, Choe J, Choi SH, Sung H, Do KH. Radiographic and CT features of viral pneumonia. RadioGraphics 2018; 38:719–739
Toplam 7 adet kaynakça vardır.

Ayrıntılar

Birincil Dil İngilizce
Konular Klinik Tıp Bilimleri, İç Hastalıkları
Bölüm Araştırma Makaleleri
Yazarlar

Serdar Serinsöz 0000-0002-0717-5722

Cahit Demir Bu kişi benim

Yayımlanma Tarihi 30 Haziran 2020
Yayımlandığı Sayı Yıl 2020 Cilt: 5 Sayı: 2

Kaynak Göster

APA Serinsöz, S., & Demir, C. (2020). Common clinical manifestations and the Thorax CT features of Coronavirus Disease 2019 (Covid-19) by stages. Journal of Immunology and Clinical Microbiology, 5(2), 63-72.
AMA Serinsöz S, Demir C. Common clinical manifestations and the Thorax CT features of Coronavirus Disease 2019 (Covid-19) by stages. J Immunol Clin Microbiol. Haziran 2020;5(2):63-72.
Chicago Serinsöz, Serdar, ve Cahit Demir. “Common Clinical Manifestations and the Thorax CT Features of Coronavirus Disease 2019 (Covid-19) by Stages”. Journal of Immunology and Clinical Microbiology 5, sy. 2 (Haziran 2020): 63-72.
EndNote Serinsöz S, Demir C (01 Haziran 2020) Common clinical manifestations and the Thorax CT features of Coronavirus Disease 2019 (Covid-19) by stages. Journal of Immunology and Clinical Microbiology 5 2 63–72.
IEEE S. Serinsöz ve C. Demir, “Common clinical manifestations and the Thorax CT features of Coronavirus Disease 2019 (Covid-19) by stages”, J Immunol Clin Microbiol, c. 5, sy. 2, ss. 63–72, 2020.
ISNAD Serinsöz, Serdar - Demir, Cahit. “Common Clinical Manifestations and the Thorax CT Features of Coronavirus Disease 2019 (Covid-19) by Stages”. Journal of Immunology and Clinical Microbiology 5/2 (Haziran 2020), 63-72.
JAMA Serinsöz S, Demir C. Common clinical manifestations and the Thorax CT features of Coronavirus Disease 2019 (Covid-19) by stages. J Immunol Clin Microbiol. 2020;5:63–72.
MLA Serinsöz, Serdar ve Cahit Demir. “Common Clinical Manifestations and the Thorax CT Features of Coronavirus Disease 2019 (Covid-19) by Stages”. Journal of Immunology and Clinical Microbiology, c. 5, sy. 2, 2020, ss. 63-72.
Vancouver Serinsöz S, Demir C. Common clinical manifestations and the Thorax CT features of Coronavirus Disease 2019 (Covid-19) by stages. J Immunol Clin Microbiol. 2020;5(2):63-72.

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