Evaluation Of Antimicrobial Activities Of Extract From Johrenıa Paucijuga (D.C.) Bornm

Yıl 2022, Cilt: 7 Sayı: 1, 1 - 4, 29.03.2022

Husniya Mammadova Ema Agayeva Vidadi Narimanov

Öz

Background: J.paucijuga (D.C.) Bornm is known to grow in Azerbaijan. Our investigation has revealed a new distribution area situated in the Gadabay region –Middle Mountain Beltgrasslands of Small Caucasus. The purpose of the study was to evaluate antimicrobial
activities of extracts from J.pucijuga (D.C.) Bornm.
Materials and Methods: The plant was collected in July 2017 and further investigated for chemical composition. Results of scientific trips have revealed the expansion of the distribution range of some plants and the reduction of other members of the Apiaceae family. Investigations related to the selection of medicinal plants, identification of their biological features, investigation of species ontogenesis, distribution range, chemical composition, evaluation of biological and exploitation reserves are always of importance. Chemical compounds characteristic of this plant - β-sitosterol and β-stigmasterol were detected in our previous research. Extract obtained from J.paucijuga (D.C.) Bornm was tested for antimicrobial activity using the disk diffusion method as a part of the cooperation between the Department of Plant Resources of İnstitute of Botany of Azerbaijan National Sciences Academy and the Department of Medical Microbiology.
Results: Thus, the study of bactericide and fungicide activity of J.pucijuga extract has shown that the aqueous extract of this plant (1:10) has antimicrobial and antifungal activity against experimental strains depending on the concentration of the extract of the plant and exposure time. J.paucijuga essential oils have shown comparatively higher bactericide activity.
Conclusions: The purpose of the study was to evaluate antimicrobial activities of extracts from J.pucijuga (D.C.) Bornm to use it in the prophylaxis of bacterial diseases as preparation antimicrobial hygienic solutions, antibacterial and antifungal ointment. The obtained formula 2 proves that the structural formula of coumarin is the same as the structure formula we are identified [8].

Anahtar Kelimeler

Johrenia paucijuga (D.C.) Bornm, Apiaceae Lindl, antimicrobial, antifungal, β-stigmasterol

Evaluation Of Antimicrobial Activities Of Extract From Johrenıa Paucijuga (D.C.) Bornm

Öz

Kaynakça

• 1. Flora Azerbaijan. Baku, 1955, T.VI, pp. 476-477, 504-505.
• 2. Askerov AM High plants of Azerbaijan (Concept of the flora of Azerbaijan II), Baku 2006, p.
• 3. Grossheim AA Caucasus Operator // Search: Nauka, M., 1949, p. 41-44.
• 4. Mammadova HG, Serkerov SV, Alasgarova AN (2018) Investigation of Biologically Active Substances Obtained from Johrenia paucijuga (DC) of the Species Bornm. Jplant Biochem Physiol 5: 209.
• 5. Serkerov SV, Aleskerova AN Infrared spectra and streaks of lactones and gambines. Baku 2006, p.223.
• 6. Gasimova GQ, Sarkarov SV Peucedanum ruthenicumbieb. of the roots. Proceedings of the Institute of Botany of ANAS, 2012 Volume XXXII, pp. 101-14.
• 7. Garayev Z., Bayramov R. Medical Microbiology Guidance of practical lessons on immunology and clinical microbiology, first edition. Baku-2011, pp.566-567.
• 8. Andreeva IV, Strachinsky LS et al. Samostatinelimitic application of antimicrobial preparations: multidimensional remodeling // Clinical Pharmacology and Therapy, 2002. Т.11, № 2, p.25-29
• 9. Glushchenko NN Patent № 2446810 RF "Antimicrobial Agent" / NN Glushchenko, OA Bogoslovskaya Glushchenko et al. №2010127540 / 15, update.06.07.10. Bulletin No. 10.
• 10. Garayev Z., Kurbanov AI Medical microbiology and immunology. Baku 2010, p.418.
• 11. Zeynalova SQ, Ahmedov IB, Bayramov AK Managing practice in medical microbiology and immunology. Baku 2007, p.95.
• 12. Aliyev NN, Hakhiyeva AN, Papashvili YA, Alakbarova LM, Ibrahimkhalilova NE, Darabi LH, Zeynalov Sh. Study of the bactericidal effect of essential oils obtained from mountain mint on bacteria and fungi. Proceedings of the Scientific Research Institute of Preventive Medicine named after VY Akhundov of the Ministry of Health of the Republic of Azerbaijan, Baku-2017, p. 17-18.
• 13.Ginzberg AS Uploshenny sposoby definition of essential oils in efironosah.
• 14. Goryaev MI Eferniye flora of the USSR. Almaty: AN Kazak SSR, 1952,378 p.