Ectoine: From Microbial Survival Secret to Biotechnological Applications

Öz

Ectoine, a compatible solute produced by physiologically and taxonomically diverse microorganism species in response to environmental stress factors such as high salinity or extreme temperatures, is a natural compound of great interest, especially in the fields of microbiology, biotechnology and environmental science. Numerous studies have been conducted to elucidate the processes underlying the cellular synthesis of ectoine, and to define its roles in stress adaptation. Ectoin, which attracted the attention of researchers due to its extraordinary biotechnological potential, finds widespread use in various sectors, especially in the cosmetic and pharmaceutical industries. While this situation accelerates studies on the discovery of new species with high ectoine production potential, it also encourages the development of cost-effective and sustainable methods for large-scale ectoine production strategies from microbial sources. This review provides a comprehensive overview of ectoine's current areas of application, highlighting its evolving role in various industries and positioning ectoine as a versatile and effective compound with far-reaching effects.

Anahtar Kelimeler

• Pharmaceuticals
• Cosmetics
• Stress adaptation
• Compatible solute

Ektoin: Mikrobiyal Hayatta Kalma Sırrından Biyoteknolojik Uygulamalara

Öz

Fizyolojik ve taksonomik açıdan oldukça büyük çeşitlilik sergileyen mikroorganizma türleri tarafından yüksek tuzluluk veya aşırı sıcaklık gibi çevresel stres faktörlerine yanıt olarak üretilen uyumlu çözünenlerden olan ektoin, özellikle mikrobiyoloji, biyoteknoloji ve çevre bilimi alanlarında büyük ilgi gören doğal bir bileşiktir. Olumsuz koşullar altında hücresel bütünlüğün ve işlevselliğin korunması açısından oldukça kritik bir molekül olan ektoinin hücresel sentezinin arkasında yatan mekanizmaların aydınlatılmasına ve stres adaptasyonundaki rollerinin tanımlanmasına yönelik pek çok çalışma gerçekleştirilmiştir. Sergilediği olağanüstü biyoteknolojik potansiyele bağlı olarak araştırmacıların dikkatini çeken ektoin başta kozmetik ve ilaç endüstrileri olmak üzere çeşitli sektörlerde yaygın kullanım alanı bulmaktadır. Bu durum bir yandan yüksek ektoin üretim potansiyeline sahip yeni türlerin keşfedilmesine yönelik çalışmalara hız kazandırırken bir yandan da mikrobiyal kaynaklardan; uygun maliyetli ve sürdürülebilir yöntemlerle büyük ölçekli ektoin üretim stratejilerinin geliştirilmesini teşvik etmektedir. Bu inceleme, bir yandan ektoinin mevcut uygulama alanlarına kapsamlı bir genel bakış sunarak çeşitli endüstrilerde gelişen rolünü vurgulamakta bir yandan da ektoini geniş kapsamlı etkilere sahip çok yönlü ve etkili bir bileşik olarak konumlandırmaktadır.

Anahtar Kelimeler

• İlaç
• Kozmetik
• Stres adaptasyonu
• Uyumlu çözünen madde

Etik Beyan

Bu makalenin yazarları, bu çalışmada kullanılan materyal ve yöntemlerin etik kurul izni ve / veya yasal-özel izin gerektirmediğini beyan etmektedir.

Teşekkür

Makalenin inceleme ve değerlendirme aşamasında yapmış oldukları katkılardan dolayı editör ve hakem/hakemlere teşekkür ederiz.

Kaynakça

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