Katalizörsüz Ortamda Benzaldehit Türevlerinin Malononitril Eşliğinde Knoevenagel Kondenzasyonu: Disiyano Bileşiklerinin Sentezi İçin Yeşil Kimya Yasalarına Uygun Etkin Bir Yöntem

Öz

Bu çalışmada aril aldehitlerin malonitril ile katalizörsüz ortamda, sadece çözücü olarak su/metanol karışımı kullanılmasıyla gerçekleştirdiği tepkime sonucu ilgili benzilidenmalononitril türevleri 15 dakikada oda sıcaklığında kantitatif verimlerle elde edilmiştir. Knoevenagel kondenzasyonu ile benzilidenmalononitril bileşiklerinin eldesi ile ilgili literatürde birçok yöntem bulunmasına rağmen, bu çalışmada herhangi bir katalizör kullanılmaması bu çalışmayı yeşil kimya yasalarına uyan etkin bir yöntem olarak ön plana çıkarmaktadır. 

Anahtar Kelimeler

• Knoevenagel kondenzasyonu,yeşil kimya,malononitril,aldehit

Catalyst Free Knoevenagel Condensation of Benzaldehyde Derivatives with Malononitrile: A Facile and Compatible Method with Green Chemistry Rules for the Synthesis of Dicyano Compounds

Öz

In this study, as a result of the reaction of aryl aldehydes with malononitrile in a catalyst-free condition by using only water/methanol mixture as a solvent, the corresponding benzylidenemalononitrile derivatives were obtained in quantitative yields at room temperature just in 15 minutes. Although many methods have been found in the literature about Knoevenagel Condensation, addressed herein a catalyst free methodology which is in harmony with the green chemistry rules makes this work effective than the others. 

Anahtar Kelimeler

• Knoevenagel Condensation,Green Chemistry,malononitrile,aldehyde

Kaynakça

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