The Acidity Strengths of 3-(4-Aryl) Propionic Acid Derivatives in Amphiprotic and Dipolar Aprotic Solvents

Öz

The acidic properties of five 3-(4-aryl) propionic acid derivatives were investigated. In this study, ethanol, tert‐butanol and water were used as an amphiprotic solvent. Aceton and N,N‐dimethylformamide (DMF) were preferred as a dipolar aprotic solvent. Compounds were titrated with tetrabuthylamonnium hydroxide (TBAH) in methyl alcohol and titrimetric analyses were used potentiometric method determining the end-points, half-neutralization method determining acidity. Typical S-shaped titration graphs excepted were determined. The acidity strengths of propionic acid derivatives in amphiprotic and dipolar aprotic solvents were calculated using tables and graphs. The pKa values obtained in the solvents were found to be differentiated. The effects of solvent, molecular structure, autoprotolysis constant dielectric constant, and leveling‐differentiation effects of the solvents upon acidity strength of the compounds were discussed.

Anahtar Kelimeler

• Amphiprotic solvent
• 3-(4-aryl) propionic acid
• Acidity strength
• Half‐neutralization method

Amfiprotik ve Dipolar Aprotik Çözücülerde 3-(4-Aril) Propiyonik Asit Türevlerinin Asitlik Kuvvetleri

Öz

Beş adet 3-(4-aril) propiyonik asit türevinin asitlik özellikleri incelenmiştir. Bu çalışmada amfiprotik çözücülerden etanol, tert‐butanol ve su, dipolaraprotik çözücülerden N,N dimetilformamid (DMF), aseton kullanılmıştır. Bileşikler tetrabutilamonyum hidroksidin (TBAH) metanoldeki çözeltisi ile titre edilmiş ve titrasyonlarda dönüm noktasının belirlenmesinde potansiyometrik metod, asitliğin belirlenmesinde yarı nötralizasyon metodu kullanılmıştır. Titrasyon eğrilerinin beklendiği gibi S şeklinde olduğu belirlenmiştir. Çizelge ve grafikler kullanılarak propiyonik asit türevlerinin amfiprotik ve dipolar aprotik çözücülerdeki asitlik kuvvetleri hesaplanmıştır. Çözücülerde elde edilen pKa değerlerinin farklandırıldığı görülmüştür. Bileşiklerin asitlik kuvvetlerine çözücü, moleküler yapı, otoprotoliz sabiti, dielektrik sabiti ve çözücünün seviyeleme-farklandırma etkileri tartışılmıştır.

Anahtar Kelimeler

• 3-(4-aril)propiyonik asit
• amfiprotik çözücü
• asitlik kuvveti
• yarı nötralizasyon metodu

Kaynakça

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